Critical Role of Jak2 in the Maintenance and Function of Adult Hematopoietic Stem Cells

Kit Regulates Maintenance of Quiescent Hematopoietic Stem Cells

(2014) L. A. Thoren et al.   JOURNAL OF IMMUNOLOGY

Erk1 and Erk2 are required for maintenance of hematopoietic stem cells and adult hematopoiesis

(2013) G. Chan et al.   BLOOD

Conditional Deletion of Jak2 Reveals an Essential Role in Hematopoiesis throughout Mouse Ontogeny: Implications for Jak2 Inhibition in Humans

(2013) Sung O. Park et al.   PLoS One

Pim1 Serine/Threonine Kinase Regulates the Number and Functions of Murine Hematopoietic Stem Cells

(2013) Ningfei An et al.   STEM CELLS

mTOR Complex 1 Plays Critical Roles in Hematopoiesis and Pten-Loss-Evoked Leukemogenesis

(2012) Demetrios Kalaitzidis et al.   Cell Stem Cell

Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk

(2012) Karl Staser et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function

(2011) Y. Zhang et al.   BLOOD

Safety and Efficacy of TG101348, a Selective JAK2 Inhibitor, in Myelofibrosis

(2011) Animesh Pardanani et al.   JOURNAL OF CLINICAL ONCOLOGY

Long-Term Outcome of Treatment with Ruxolitinib in Myelofibrosis

(2011) Ayalew Tefferi et al.   NEW ENGLAND JOURNAL OF MEDICINE

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species

(2010) M. M. Juntilla et al.   BLOOD

Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis

(2009) F. P. S. Santos et al.   BLOOD

Myeloproliferative disorders

(2008) R. L. Levine et al.   BLOOD

Pbx1 Regulates Self-Renewal of Long-Term Hematopoietic Stem Cells by Maintaining Their Quiescence

(2008) Francesca Ficara et al.   Cell Stem Cell

Cytokines regulating hematopoietic stem cell function

(2008) Cheng C Zhang et al.   CURRENT OPINION IN HEMATOLOGY

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE