A small molecule p75NTRligand protects neurogenesis after traumatic brain injury

Oral Administration of a Small Molecule Targeted to Block proNGF Binding to p75 Promotes Myelin Sparing and Functional Recovery after Spinal Cord Injury

(2013) C. Tep et al.   JOURNAL OF NEUROSCIENCE

Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease

(2013) Frank M. Longo et al.   NATURE REVIEWS DRUG DISCOVERY

A small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model

(2013) Juliet K. Knowles et al.   NEUROBIOLOGY OF AGING

Long-Term Upregulation of Inflammation and Suppression of Cell Proliferation in the Brain of Adult Rats Exposed to Traumatic Brain Injury Using the Controlled Cortical Impact Model

(2013) Sandra A. Acosta et al.   PLoS One

Impact of inhibition of erythropoietin treatment-mediated neurogenesis in the dentate gyrus of the hippocampus on restoration of spatial learning after traumatic brain injury

(2012) Yanlu Zhang et al.   EXPERIMENTAL NEUROLOGY

Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor

(2012) Joana C d’Avila et al.   Journal of Neuroinflammation

BDNF Promotes Differentiation and Maturation of Adult-born Neurons through GABAergic Transmission

(2012) E. G. Waterhouse et al.   JOURNAL OF NEUROSCIENCE

Optical controlling reveals time-dependent roles for adult-born dentate granule cells

(2012) Yan Gu et al.   NATURE NEUROSCIENCE

p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity

(2012) Carlos F. Ibáñez et al.   TRENDS IN NEUROSCIENCES

Dentate gyrus neurogenesis, integration and microRNAs

(2011) Bryan W. Luikart et al.   BEHAVIOURAL BRAIN RESEARCH

Erythropoietin promotes neurovascular remodeling and long-term functional recovery in rats following traumatic brain injury

(2011) Ruizhuo Ning et al.   BRAIN RESEARCH

Suppression of Immunodeficiency Virus-Associated Neural Damage by the p75 Neurotrophin Receptor Ligand, LM11A-31, in an In Vitro Feline Model

(2011) Rick B. Meeker et al.   Journal of Neuroimmune Pharmacology

Temporally Specified Genetic Ablation of Neurogenesis Impairs Cognitive Recovery after Traumatic Brain Injury

(2011) C. A. Blaiss et al.   JOURNAL OF NEUROSCIENCE

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

Time-Lapse Imaging Reveals Symmetric Neurogenic Cell Division of GFAP-Expressing Progenitors for Expansion of Postnatal Dentate Granule Neurons

(2011) Takashi Namba et al.   PLoS One

Brain-derived neurotrophic factor in traumatic brain injury, post-traumatic stress disorder, and their comorbid conditions: role in pathogenesis and treatment

(2010) Gary B. Kaplan et al.   BEHAVIOURAL PHARMACOLOGY

The p75 neurotrophin receptor is expressed by adult mouse dentate progenitor cells and regulates neuronal and non-neuronal cell genesis

(2010) Ramon O Bernabeu et al.   BMC NEUROSCIENCE

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

(2010) Stephen M. Massa et al.   JOURNAL OF CLINICAL INVESTIGATION

Treatment of traumatic brain injury with thymosin β4 in rats

(2010) Ye Xiong et al.   JOURNAL OF NEUROSURGERY

Signaling of the neurotrophin receptor p75 in relation to Alzheimer’s disease

(2009) Adama Diarra et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Brain-Derived Neurotrophic Factor (BDNF) has Proliferative Effects on Neural Stem Cells through the Truncated TRK-B Receptor, MAP Kinase, AKT, and STAT-3 Signaling Pathways

(2009) Omedul Islam et al.   CURRENT NEUROVASCULAR RESEARCH

The p75 Neurotrophin Receptor Promotes Amyloid- (1-42)-Induced Neuritic Dystrophy In Vitro and In Vivo

(2009) J. K. Knowles et al.   JOURNAL OF NEUROSCIENCE

Forebrain neurogenesis after focal Ischemic and traumatic brain injury

(2009) Steven G. Kernie et al.   NEUROBIOLOGY OF DISEASE

p75 neurotrophin receptor regulates basal and fluoxetine-stimulated hippocampal neurogenesis

(2009) Michael J. Colditz et al.   EXPERIMENTAL BRAIN RESEARCH

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

Small Molecule Modulation of p75 Neurotrophin Receptor Functions

(2008) Frank Longo et al.   CNS & Neurological Disorders-Drug Targets

The p75 neurotrophin receptor regulates hippocampal neurogenesis and related behaviours

(2008) Vibeke S. Catts et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Traumatic Brain Injury-Induced Hippocampal Neurogenesis Requires Activation of Early Nestin-Expressing Progenitors

(2008) T.-S. Yu et al.   JOURNAL OF NEUROSCIENCE

Brain-Derived Neurotrophic Factor Signaling Does Not Stimulate Subventricular Zone Neurogenesis in Adult Mice and Rats

(2008) R. P. Galvao et al.   JOURNAL OF NEUROSCIENCE

Selective death of newborn neurons in hippocampal dentate gyrus following moderate experimental traumatic brain injury

(2008) Xiang Gao et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effects of erythropoietin on reducing brain damage and improving functional outcome after traumatic brain injury in mice

(2008) Ye Xiong et al.   JOURNAL OF NEUROSURGERY

Simvastatin-Mediated Upregulation of VEGF and BDNF, Activation of the PI3K/Akt Pathway, and Increase of Neurogenesis Are Associated with Therapeutic Improvement after Traumatic Brain Injury

(2008) Hongtao Wu et al.   JOURNAL OF NEUROTRAUMA

Aβ1–42 stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor

(2008) Areechun Sotthibundhu et al.   NEUROBIOLOGY OF AGING

TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment

(2008) Yun Li et al.   NEURON

Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants

(2008) Sarah E. James et al.   NEUROTOXICOLOGY

Small Molecule, Non-Peptide p75NTR Ligands Inhibit Aβ-Induced Neurodegeneration and Synaptic Impairment

(2008) Tao Yang et al.   PLoS One

The p75 neurotrophin receptor

(2007) Clare K. Underwood et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY