Concise Review: Hematopoietic Stem Cell Transplantation: Targeting the Thymus

Evidence That Androgens Modulate Human Thymic T Cell Output

(2016) Nancy J. Olsen et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Intrathymic progenitor cell transplantation across histocompatibility barriers results in the persistence of early thymic progenitors and T-cell differentiation

(2013) S. C. de Barros et al.   BLOOD

Early T-cell progenitors are the major granulocyte precursors in the adult mouse thymus

(2012) M. E. De Obaldia et al.   BLOOD

Recombinant human interleukin-7 (CYT107) promotes T-cell recovery after allogeneic stem cell transplantation

(2012) M.-A. Perales et al.   BLOOD

Outcome of hematopoietic stem cell transplantation for adenosine deaminase-deficient severe combined immunodeficiency

(2012) A. Hassan et al.   BLOOD

Thymocytes may persist and differentiate without any input from bone marrow progenitors

(2012) Laetitia Peaudecerf et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thymus-autonomous T cell development in the absence of progenitor import

(2012) Vera C. Martins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential

(2012) Sidinh Luc et al.   NATURE IMMUNOLOGY

Interleukin-22 Drives Endogenous Thymic Regeneration in Mice

(2012) J. A. Dudakov et al.   SCIENCE

Greater than the sum of their parts: Combination strategies for immune regeneration following allogeneic hematopoietic stem cell transplantation

(2011) Jarrod A. Dudakov et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

A simplified intrathymic injection technique for mice

(2011) LL Liu et al.   BIOTECHNIC & HISTOCHEMISTRY

Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation

(2011) D. A. Zlotoff et al.   BLOOD

Immune reconstitution under antiretroviral therapy: the new challenge in HIV-1 infection

(2011) P. Corbeau et al.   BLOOD

Pre-differentiated human committed T-lymphoid progenitors promote peripheral T-cell re-constitution after stem cell transplantation in immunodeficient mice

(2011) Matthias Eyrich et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors

(2010) L. I. Richie Ehrlich et al.   BLOOD

First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases

(2010) M. L. Markert et al.   BLOOD

Getting back at nature: understanding thymic development and overcoming its atrophy

(2010) Tracy SP Heng et al.   CURRENT OPINION IN PHARMACOLOGY

Thymic recovery after allogeneic hematopoietic cell transplantation with non-myeloablative conditioning is limited to patients younger than 60 years of age

(2010) E. Castermans et al.   HAEMATOLOGICA

Fate Mapping Reveals Separate Origins of T Cells and Myeloid Lineages in the Thymus

(2010) Susan M. Schlenner et al.   IMMUNITY

Transplantation of hematopoietic stem cells and long-term survival for primary immunodeficiencies in Europe: Entering a new century, do we do better?

(2010) Andrew R. Gennery et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An alternative method for intrathymic injections in mice

(2010) Robin Blair-Handon et al.   LAB ANIMAL

Characterization in vitro and engraftment potential in vivo of human progenitor T cells generated from hematopoietic stem cells

(2009) G. Awong et al.   BLOOD

Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation

(2009) R. M. Kelly et al.   BLOOD

Intrathymic transplantation of bone marrow-derived progenitors provides long-term thymopoiesis

(2009) R. Vicente et al.   BLOOD

CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus

(2009) D. A. Zlotoff et al.   BLOOD

CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus

(2009) A. Krueger et al.   BLOOD

In vitro-differentiated T/natural killer-cell progenitors derived from human CD34+ cells mature in the thymus

(2009) B. Meek et al.   BLOOD

Evolution of Genetic Networks Underlying the Emergence of Thymopoiesis in Vertebrates

(2009) Baubak Bajoghli et al.   CELL

Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation

(2008) R. M. Kelly et al.   BLOOD

Efficient Intrathymic Gene Transfer Following In Situ Administration of a rAAV Serotype 8 Vector in Mice and Nonhuman Primates

(2008) Aurélie Moreau et al.   MOLECULAR THERAPY

Adult T-cell progenitors retain myeloid potential

(2008) Haruka Wada et al.   NATURE

The earliest thymic progenitors for T cells possess myeloid lineage potential

(2008) J. Jeremiah Bell et al.   NATURE

Antibody responses of variable lymphocyte receptors in the lamprey

(2008) Matthew N Alder et al.   NATURE IMMUNOLOGY