Action at a Distance: Systemically Administered Adult Stem/Progenitor Cells (MSCs) Reduce Inflammatory Damage to the Cornea Without Engraftment and Primarily by Secretion of TNF-α Stimulated Gene/Protein 6

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF- B signaling in resident macrophages

(2011) H. Choi et al.   BLOOD

Mesenchymal stem cells for acute lung injury: Preclinical evidence

(2010) Michael A. Matthay et al.   CRITICAL CARE MEDICINE

Why should mesenchymal stem cells (MSCs) cure autoimmune diseases?

(2010) Antonio Uccelli et al.   CURRENT OPINION IN IMMUNOLOGY

Congenic Mesenchymal Stem Cell Therapy Reverses Hyperglycemia in Experimental Type 1 Diabetes

(2010) M. Jurewicz et al.   DIABETES

Evolving paradigms for repair of tissues by adult stem/progenitor cells (MSCs)

(2010) Darwin J. Prockop et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Reactive Bone Marrow Stromal Cells Attenuate Systemic Inflammation via sTNFR1

(2010) Hiroshi Yagi et al.   MOLECULAR THERAPY

Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury

(2010) J. Y. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties

(2010) T. J. Bartosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Umbilical Cord Mesenchymal Stem Cells Reduce Fibrosis of Bleomycin-Induced Lung Injury

(2009) Yuben Moodley et al.   AMERICAN JOURNAL OF PATHOLOGY

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

Why are MSCs therapeutic? New data: new insight

(2008) AI Caplan   JOURNAL OF PATHOLOGY

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE

Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses

(2008) H. Ohtaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Anti-Inflammatory and Anti-Angiogenic Role of Mesenchymal Stem Cells in Corneal Wound Healing Following Chemical Injury

(2008) Joo Youn Oh et al.   STEM CELLS