An innovative hydrogel of gemcitabine-loaded lipid nanocapsules: when the drug is a key player of the nanomedicine structure

Injectable intratumoral hydrogel as 5-fluorouracil drug depot

(2013) Hyo Won Seo et al.   BIOMATERIALS

Lysosomal Delivery of a Lipophilic Gemcitabine Prodrug Using Novel Acid-Sensitive Micelles Improved Its Antitumor Activity

(2012) Saijie Zhu et al.   BIOCONJUGATE CHEMISTRY

Solid lipid nanoparticles (SLN) - based hydrogels as potential carriers for oral transmucosal delivery of Risperidone: Preparation and characterization studies

(2012) A.C. Silva et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

siRNA LNCs – A novel platform of lipid nanocapsules for systemic siRNA administration

(2012) Stephanie David et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Brain tumour targeting strategies via coated ferrociphenol lipid nanocapsules

(2012) Anne-Laure Laine et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Inhibition of AKT2 Enhances Sensitivity to Gemcitabine via Regulating PUMA and NF-κB Signaling Pathway in Human Pancreatic Ductal Adenocarcinoma

(2012) Dong Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Design, optimization and in vitro evaluation of reverse micelle-loaded lipid nanocarriers containing erlotinib hydrochloride

(2012) Sandy Vrignaud et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Gemcitabine versus Modified Gemcitabine: A Review of Several Promising Chemical Modifications

(2012) Elodie Moysan et al.   MOLECULAR PHARMACEUTICS

Influence of size, surface coating and fine chemical composition on the in vitro reactivity and in vivo biodistribution of lipid nanocapsules versus lipid nanoemulsions in cancer models

(2012) Samuli Hirsjärvi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Designing Cell-Compatible Hydrogels for Biomedical Applications

(2012) D. Seliktar   SCIENCE

Novel supramolecular hydrogel/micelle composite for co-delivery of anticancer drug and growth factor

(2012) Dong Ma et al.   Soft Matter

Lymphatic drug delivery using engineered liposomes and solid lipid nanoparticles

(2011) Shuang Cai et al.   ADVANCED DRUG DELIVERY REVIEWS

Tumor eradication in rat glioma and bypass of immunosuppressive barriers using internal radiation with 188Re-lipid nanocapsules

(2011) Claire Vanpouille-Box et al.   BIOMATERIALS

Strategies for the nanoencapsulation of hydrophilic molecules in polymer-based nanoparticles

(2011) Sandy Vrignaud et al.   BIOMATERIALS

Gemcitabine-loaded innovative nanocarriers vs GEMZAR: Biodistribution, pharmacokinetic features andin vivoantitumor activity

(2011) Christian Celia et al.   Expert Opinion on Drug Delivery

In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticles

(2011) Brian R. Sloat et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133

(2011) E. Bourseau-Guilmain et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

EGFR-targeted stearoyl gemcitabine nanoparticles show enhanced anti-tumor activity

(2011) Michael A. Sandoval et al.   JOURNAL OF CONTROLLED RELEASE

Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1

(2011) Woon-Gye Chung et al.   JOURNAL OF CONTROLLED RELEASE

Methanol Strengthens Hydrogen Bonds and Weakens Hydrophobic Interactions in Proteins – A Combined Molecular Dynamics and NMR study

(2011) Soyoun Hwang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The importance of endo-lysosomal escape with lipid nanocapsules for drug subcellular bioavailability

(2010) Archibald Paillard et al.   BIOMATERIALS

Tumor transfection after systemic injection of DNA lipid nanocapsules

(2010) Marie Morille et al.   BIOMATERIALS

Liposomal squalenoyl-gemcitabine: formulation, characterization and anticancer activity evaluation

(2010) Barbara Pili et al.   Nanoscale

Masitinib Combined with Standard Gemcitabine Chemotherapy: In Vitro and In Vivo Studies in Human Pancreatic Tumour Cell Lines and Ectopic Mouse Model

(2010) Martine Humbert et al.   PLoS One

Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases

(2009) I. F. Robey et al.   CANCER RESEARCH

Aqueous-Core Lipid Nanocapsules for Encapsulating Fragile Hydrophilic and/or Lipophilic Molecules

(2009) Nicolas Anton et al.   LANGMUIR

Liposome−Hydrogel Bead Complexes Prepared via Biotin−Avidin Conjugation

(2009) Neil MacKinnon et al.   LANGMUIR

Novel Approaches to Deliver Gemcitabine to Cancers

(2008) L. Reddy et al.   CURRENT PHARMACEUTICAL DESIGN

188Re-loaded lipid nanocapsules as a promising radiopharmaceutical carrier for internal radiotherapy of malignant gliomas

(2008) E. Allard et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Human Equilibrative Nucleoside Transporter 1 Levels Predict Response to Gemcitabine in Patients With Pancreatic Cancer

(2008) James J. Farrell et al.   GASTROENTEROLOGY

Hydrogels in drug delivery: Progress and challenges

(2008) Todd R. Hoare et al.   POLYMER