Inhibition of AKT2 Enhances Sensitivity to Gemcitabine via Regulating PUMA and NF-κB Signaling Pathway in Human Pancreatic Ductal Adenocarcinoma

Overcoming drug resistance in pancreatic cancer

(2011) Jiang Long et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Akt Requires Glucose Metabolism to Suppress Puma Expression and Prevent Apoptosis of Leukemic T Cells

(2010) Jonathan L. Coloff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Slug inhibition upregulates radiation-induced PUMA activity leading to apoptosis in cholangiocarcinomas

(2010) Kejun Zhang et al.   MEDICAL ONCOLOGY

Pancreatic Cancer

(2010) Manuel Hidalgo   NEW ENGLAND JOURNAL OF MEDICINE

Curative Radiation Therapy for Pancreatic Malignancies

(2010) Ellen W. Cooke et al.   SURGICAL CLINICS OF NORTH AMERICA

Downregulation of nuclear factor-κB p65 subunit by small interfering RNA synergizes with gemcitabine to inhibit the growth of pancreatic cancer

(2009) Rui Kong et al.   CANCER LETTERS

Akt inhibitors induce apoptosis in chronic lymphocytic leukemia cells

(2009) M. de Frias et al.   HAEMATOLOGICA

Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells

(2009) G. L. Gallia et al.   MOLECULAR CANCER THERAPEUTICS

Down-regulation of Phospho-Akt Is a Major Molecular Determinant of Bortezomib-Induced Apoptosis in Hepatocellular Carcinoma Cells

(2008) K.-F. Chen et al.   CANCER RESEARCH

Nuclear Factor- B p65/relA Silencing Induces Apoptosis and Increases Gemcitabine Effectiveness in a Subset of Pancreatic Cancer Cells

(2008) X. Pan et al.   CLINICAL CANCER RESEARCH

Effect of Rapamycin Alone and in Combination with Sorafenib in an Orthotopic Model of Human Hepatocellular Carcinoma

(2008) Z. Wang et al.   CLINICAL CANCER RESEARCH

Phosphatidylinositol 3-Kinase/AKT Pathway Regulates the Endoplasmic Reticulum to Golgi Traffic of Ceramide in Glioma Cells

(2008) Paola Giussani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metastatic Pancreatic Cancer 2008: Is the Glass Less Empty?

(2008) J. Nieto et al.   ONCOLOGIST