Article
Polymer Science
Yucheng Zhang, Atsushi Takahara
Summary: Amphiphilic copolymers containing superhydrophobic and superhydrophilic segments were designed and synthesized, showing different molecular aggregation structures and thermal stability. The polymeric film of P(FA-C-8-ran-MAPS) exhibited strong oleophobicity under both air and water conditions.
Article
Nanoscience & Nanotechnology
Frieda Nagler, Christine Schiller, Christian Kropf, Felix H. Schacher
Summary: In this study, polymers were investigated as encapsulation agents for controlled or delayed release of perfumes. Two amphiphilic graft copolymers with different hydrophobic side chains were used to adsorb different types of fragrances. The side-chain density did not significantly affect the loading, and different analytical methods were compared for characterization and quantification. It was also found that the aromatic fragrance could be loaded into the graft copolymer with aliphatic side chains. This study demonstrates the potential of tailored polyampholytic graft copolymers for adsorption of various hydrophobic perfumes.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Physical
Pablo I. Sepulveda-Medina, Madhusudan Tyagi, Chao Wang, Bryan D. Vogt
Summary: The dynamics of water in amphiphilic hydrogels are influenced by secondary confinement, with changes in composition affecting the spacing between cross-links and altering the temperature dependent dynamics of water. Despite lower water crystallinity, the self-diffusion coefficient of these hydrogels decreases significantly below 260 K, suggesting a chemistry dependent dynamics of water in confined environments.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Polymer Science
Victor Delorme, Ghislain David, Stephane Dejean, Julia Mouton, Xavier Garric, Jean Coudane, Helene van den Berghe
Summary: Describes the synthesis of a fully biodegradable amphiphilic copolymer PCL-g-CHT, which has a hydrophobic PCL backbone and hydrophilic CHT grafts. The copolymer self-assembles into nanomicelles and can be used for novel drug delivery systems.
MACROMOLECULAR RAPID COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Teng Wang, Jiawen Zhang, Ying Cai, Lang Xu, Lingmin Yi
Summary: This study demonstrates that molecular-scale compositional heterogeneities can reduce the nonspecific interaction between proteins and surfaces, leading to improved resistance against surface contamination. The balance between hydrophilic and hydrophobic segments on the surface of the copolymer coatings provides better synergistic effects, resulting in excellent resistance to various proteins.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Zhihao Feng, Yifan Cheng, Alexandra Khlyustova, Aasim Wani, Trevor Franklin, Jeffrey D. Varner, Andrew L. Hook, Rong Yang
Summary: Amphiphilic copolymers (AP) are a class of antibiofouling materials that can be optimized by tuning their chemistry and composition. However, the large design space associated with AP makes optimization laborious. To address this, a machine learning approach is used to accurately predict biofilm formation on a library of AP, expanding the accessible design space and identifying best-performing candidates for experimental validation.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Biophysics
Monika Holubova, Juraj Kronek, Shubhashis Datta, Volodymyr Lobaz, Jirina Hromadkova, Petr Stepanek, Martin Hruby
Summary: This study investigated the inhibitory effects of a novel copolymer on amyloid formation and found that some gradient copolymers showed potent inhibitory effects. These copolymers may inhibit amyloid formation by interacting with the ends of amyloid fibrils instead of isolated protein molecules in solution. These findings suggest the potential use of these gradient copolymers as therapeutic agents for amyloidoses.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Review
Materials Science, Multidisciplinary
Muhammad A. Shehzad, Aqsa Yasmin, Xiaolin Ge, Liang Wu, Tongwen Xu
Summary: This article highlights the potential of ion-exchange membranes (IEMs) with tunable nanostructures for energy-efficient applications such as electrodialysis and fuel cells. It discusses the relationship between membrane nanostructures and ions permeation, summarizes the fabrication methods of nanostructured membranes and their influence on physical and ion transport properties, and explores the potential engineering and application prospects of nanostructured IEMs.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Article
Engineering, Biomedical
Dinh Chuong Nguyen, Daniel Shae, Hayden M. Pagendarm, Kyle W. Becker, Mohamed Wehbe, Kameron Kilchrist, Lucinda E. Pastora, Christian R. Palmer, Pedro Seber, Plamen P. Christov, Craig L. Duvall, John T. Wilson
Summary: The study addressed the poor drug-like properties of CDN cGAMP by synthesizing novel copolymers with pH-responsive, membrane-destabilizing activity to enhance intracellular delivery. Certain nanoparticles loaded with cGAMP significantly improved immunostimulatory activity, demonstrating efficient cytosolic delivery as a crucial criterion for CDN carriers.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Meng Wang, Hoang Nguyen, Samuel J. Lounder, Ayse Asatekin, Debora F. Rodrigues
Summary: This study investigates the mechanisms of mineral scaling prevention of ZI polymers and finds that the performance of ZAC coatings varies under different saturation indices.
ACS APPLIED POLYMER MATERIALS
(2022)
Review
Chemistry, Multidisciplinary
Philipp S. Orekhov, Marine E. Bozdaganyan, Natalia Voskoboynikova, Armen Y. Mulkidjanian, Maria G. Karlova, Anna Yudenko, Alina Remeeva, Yury L. Ryzhykau, Ivan Gushchin, Valentin I. Gordeliy, Olga S. Sokolova, Heinz-Juergen Steinhoff, Mikhail P. Kirpichnikov, Konstantin V. Shaitan
Summary: Amphiphilic copolymers with alternating hydrophilic and hydrophobic units can extract membrane proteins directly from lipid membranes, forming nanoparticles suitable for various spectroscopy and biophysical techniques. Copolymer-encased nanolipoparticles have proven to be important in structural biology applications such as cryo-electron microscopy.
Article
Polymer Science
Mingtao Zhou, Shengfei Wang, Aishun Ding, Guolin Lu, Xiaoyu Huang, Xue Jiang, Binbin Xu
Summary: This study presents the controlled synthesis of polyallene-based diblock copolymers with tunable structure and low polydispersities via reversible addition-fragmentation chain transfer (RAFT) polymerization, highlighting the in situ formation of unique nanofibers based on PNIPAM-b-PPOA diblock copolymer through polymerization-induced self-assembly (PISA). The work opens a new avenue for synthesizing well-defined polyallene-based copolymers and nanoparticles for broad applications using living/controlled radical polymerization.
Article
Polymer Science
Puja Das Karmakar, Sagar Pal
Summary: In this study, a new pH-responsive amphiphilic graft copolymer was synthesized using ROP and RAFT techniques. The copolymer can efficiently self-assemble into micelles and is suitable for delivering drugs as a nanocarrier.
Article
Chemistry, Multidisciplinary
Arjun Menon, Peter W. Muenich, Pawel Wagner, David L. Officer, Dirk M. Guldi
Summary: The study describes a novel non-covalent electron donor-acceptor system involving metalloporphyrins and SWCNT, with microscopy and spectroscopy confirming efficient charge-transfer interactions. The fastest charge-separation and recombination dynamics were observed in 2-SWCNT, showing strong interactions and fast excited state decay.
Article
Polymer Science
Ekaterina Kostyurina, Judith U. De Mel, Alexandra Vasilyeva, Margarita Kruteva, Henrich Frielinghaus, Martin Dulle, Lester Barnsley, Stephan Foerster, Gerald J. Schneider, Ralf Biehl, Juergen Allgaier
Summary: Amphiphilic polymers exhibit diverse self-assembly behaviors in aqueous solutions. The solution properties and self-assembly morphologies, including single chains, micelles, gels, and ordered liquid crystals, can be systematically tuned by adjusting the lengths of the hydrophilic and hydrophobic building blocks.
Article
Pharmacology & Pharmacy
Xia Wang, Dechao Niu, Chen Hu, Pei Li
CURRENT PHARMACEUTICAL DESIGN
(2015)
Article
Polymer Science
Noel Peter Bengzon Tan, Cheng Hao Lee, Lianghui Chen, Kin Man Ho, Yan Lu, Matthias Ballauff, Pei Li
Article
Nanoscience & Nanotechnology
Zuojin Liu, Dechao Niu, Junyong Zhang, Wenfeng Zhang, Yuan Yao, Pei Li, Jianping Gong
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2016)
Article
Chemistry, Physical
Lianghui Chen, Dechao Niu, Cheng Hao Lee, Yuan Yao, Ki Lui, Kin Man Ho, Pei Li
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
(2016)
Article
Polymer Science
Chun Ho Yam, Cheng Hao Lee, Yuen Shan Siu, Kin Man Ho, Pei Li
Article
Polymer Science
Noel Peter Bengzon Tan, Cheng Hao Lee, Pei Li
Article
Biophysics
Yuen Shan Siu, Lijun Li, Man Fai Leung, Kam Len Daniel Lee, Pei Li
Article
Chemistry, Multidisciplinary
Hetti Mimi, Kin Man Ho, Yuen Shan Siu, Aihua Wu, Pei Li
JOURNAL OF CONTROLLED RELEASE
(2012)
Article
Chemistry, Multidisciplinary
Cheng Hao Lee, Chun Him Wong, Djamila Ouhab, Redouane Borsali, Pei Li
Article
Nanoscience & Nanotechnology
Limei Qin, Dechao Niu, Yu Jiang, Jianping He, Xiaobo Jia, Wenru Zhao, Pei Li, Yongsheng Li
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2019)
Article
Polymer Science
Yuan Yao, Dechao Niu, Cheng Hao Lee, Yongsheng Li, Pei Li
MACROMOLECULAR RAPID COMMUNICATIONS
(2019)
Article
Engineering, Chemical
Suqing Tan, Albert P. C. Chan, Pei Li
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2019)
Article
Materials Science, Biomaterials
Luying Shen, Shan Pan, Dechao Niu, Jianping He, Xiaobo Jia, Jina Hao, Jinlou Gu, Wenru Zhao, Pei Li, Yongsheng Li
BIOMATERIALS SCIENCE
(2019)
Article
Chemistry, Multidisciplinary
Yanjun Jia, Dechao Niu, Qiujin Li, Hong Huang, Xinrun Li, Kejia Li, Ling Li, Cheng Zhang, Hongting Zheng, Zhiming Zhu, Yuan Yao, Xiaodong Zhao, Pei Li, Gangyi Yang
Article
Multidisciplinary Sciences
Noel Peter Bengzon Tan, Cheng Hao Lee, Pei Li
Article
Chemistry, Physical
Yiping Yin, Zhe Wang, Hua Zou
Summary: This study presents a novel method for preparing dimpled polymer-silica nanocomposite particles using interfacial swelling-based seeded polymerization. The optimized conditions allow for a relatively high percentage of dimpled particles to be achieved.
Article
Chemistry, Physical
Brenden D. Hoehn, Elizabeth A. Kellstedt, Marc A. Hillmyer
Summary: Porous materials with nanometer-scale pores have important applications as nanoporous membranes. In this study, ABA triblock copolymers were used as precursors to produce nanoporous polymeric membranes (NPMs) in thin film form by degrading the end blocks. Polycyclooctene (PCOE) NPMs with tunable pore sizes were successfully prepared using solvent casting technique. Oxygen plasma etching was employed to improve the surface porosity and hydrophilicity of the membranes. This study provides a straightforward method to produce tough NPMs with high porosity and hydrophilic surface properties.
Article
Chemistry, Physical
Vladislav S. Petrovskii, Stepan I. Zholudev, Igor I. Potemkin
Summary: This article investigates the behavior of linear and ring polypeptide chains in aqueous solution and explores the properties of the complexes formed by these chains with oppositely charged surfactants. The results demonstrate that the complexes of linear supercharged unfolded polypeptides and the corresponding surfactants exhibit impressive adhesive properties.
Article
Chemistry, Physical
Merve Cevik, Serkan Dikici
Summary: Cardiovascular diseases are a leading cause of death globally, and vascular grafts are a promising treatment option. This study focuses on tissue-engineered vascular grafts (TEVGs) using decellularized parsley stems as a potential biomaterial. The decellularized parsley stems showed suitable properties for TEVGs, providing a suitable environment for human endothelial cells to form a pseudo endothelium. This study showcases the potential of using parsley stems for TEVGs.
Article
Chemistry, Physical
Gustavo A. Vasquez-Montoya, Tadej Emersic, Noe Atzin, Antonio Tavera-Vazquez, Ali Mozaffari, Rui Zhang, Orlando Guzman, Alexey Snezhko, Paul F. Nealey, Juan J. de Pablo
Summary: The optical properties of liquid crystals are typically controlled by electric fields. In this study, we investigate the effects of microfluidic flows and acoustic fields on the molecular orientation and optical response of nematic liquid crystals. We identify several previously unknown structures and explain them through calculations and simulations. These findings hold promise for the development of new systems combining sound, flow, and confinement.
Article
Chemistry, Physical
Xinjun Wu, Xin Guan, Shushu Chen, Jiangpeng Jia, Chongyi Chen, Jiawei Zhang, Chuanzhuang Zhao
Summary: This research presents a novel shape memory hydrogel with a remodelable permanent shape and programmable cold-induced shape recovery behavior. The hydrogel is prepared using specific treatment methods to achieve shape fixation by heating and shape recovery by cooling. Additionally, deformable devices can be obtained by assembling hydrogel blocks with different concentrations.
Article
Chemistry, Physical
Rebecca Hengsbach, Gerhard Fink, Ulrich Simon
Summary: This study examines the properties of DNA functionalized pNipmam microgels and pure pNipmam microgels at different concentrations of sodium chloride and in PBS solutions using temperature dependent H-1-NMR measurements. The results show that DNA modification affects the volume phase transition temperature and the addition of salt and PBS further enhances this effect.
Article
Chemistry, Physical
Ningyi Li, Junhong Li, Lijingting Qing, Shicheng Ma, Yao Li, Baohui Li
Summary: This paper investigates the self-assembly behavior of colloids with competing interactions under spherical confinement and finds that different ordered structures can be formed under different sized spherical confinements. Moreover, more perforated structures are formed in smaller spheres.