TALEN mediated targeted editing of GM2/GD2-synthase gene modulates anchorage independent growth by reducing anoikis resistance in mouse tumor cells

Aiolos Promotes Anchorage Independence by Silencing p66Shc Transcription in Cancer Cells

(2014) Xichuan Li et al.   CANCER CELL

Making designer mutants in model organisms

(2014) Y. Peng et al.   DEVELOPMENT

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

(2014) Claudio Mussolino et al.   NUCLEIC ACIDS RESEARCH

microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition

(2014) Aditya Parikh et al.   Nature Communications

Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair

(2013) T. O. Auer et al.   GENOME RESEARCH

A library of TAL effector nucleases spanning the human genome

(2013) Yongsub Kim et al.   NATURE BIOTECHNOLOGY

Knockout mice created by TALEN-mediated gene targeting

(2013) Young Hoon Sung et al.   NATURE BIOTECHNOLOGY

Targeting Human MicroRNA Genes Using Engineered Tal-Effector Nucleases (TALENs)

(2013) Ruozhen Hu et al.   PLoS One

Targeted Myostatin Gene Editing in Multiple Mammalian Species Directed by a Single Pair of TALE Nucleases

(2013) Li Xu et al.   Molecular Therapy-Nucleic Acids

In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration

(2012) Sandra Cristea et al.   BIOTECHNOLOGY AND BIOENGINEERING

A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models

(2012) Qiurong Ding et al.   Cell Stem Cell

Obligate Ligation-Gated Recombination (ObLiGaRe): Custom-designed nuclease-mediated targeted integration through nonhomologous end joining

(2012) M. Maresca et al.   GENOME RESEARCH

FLASH assembly of TALENs for high-throughput genome editing

(2012) Deepak Reyon et al.   NATURE BIOTECHNOLOGY

CD4 and CD8 T cells require different membrane gangliosides for activation

(2012) M. Nagafuku et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impairment of neuropsychological behaviors in ganglioside GM3-knockout mice

(2011) Kimie Niimi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy

(2011) James Finke et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Move over ZFNs

(2011)   NATURE BIOTECHNOLOGY

Ganglioside synthase knockout in oncogene-transformed fibroblasts depletes gangliosides and impairs tumor growth

(2010) Y Liu et al.   ONCOGENE

Inhibition of ADAM9 expression induces epithelial phenotypic alterations and sensitizes human prostate cancer cells to radiation and chemotherapy

(2010) Sajni Josson et al.   PROSTATE

Ganglioside GM3 Is Antiangiogenic in Malignant Brain Cancer

(2010) Thomas N. Seyfried et al.   Journal of Oncology

GD3, an Overexpressed Tumor-Derived Ganglioside, Mediates the Apoptosis of Activated but not Resting T Cells

(2009) G. Sa et al.   CANCER RESEARCH

GM3 synthase overexpression results in reduced cell motility and in caveolin-1 upregulation in human ovarian carcinoma cells

(2009) A. Prinetti et al.   GLYCOBIOLOGY

Elevated Levels of Select Gangliosides in T Cells from Renal Cell Carcinoma Patients Is Associated with T Cell Dysfunction

(2009) S. Biswas et al.   JOURNAL OF IMMUNOLOGY

STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells

(2008) P. A. Cohen et al.   BLOOD

GM1 and Tumor Necrosis Factor- , Overexpressed in Renal Cell Carcinoma, Synergize to Induce T-Cell Apoptosis

(2008) T. Das et al.   CANCER RESEARCH