Article
Chemistry, Multidisciplinary
Hyoungwon Park, Jae-Hun Kim, Dustin Vivod, Sungil Kim, Ali Mirzaei, Dirk Zahn, Changkyoo Park, Sang Sub Kim, Marcus Halik
Summary: This study enhanced the sensing capabilities of semiconducting metal oxide-based gas sensors through a new post-modification method, improving gas selectivity; the chemical-affinity-driven interaction between SAM and gas molecules enabled selective gas sensing.
Article
Chemistry, Physical
Yanhui Sun, Jing Wang, Haiying Du, Xiaogan Li, Chen Wang, Tengyue Hou
Summary: The addition of zeolite on the surface of metal oxides enhances the selectivity of gas sensors, and the synthesis of SnO2/ZSM-5 composite nanofibers can improve sensor sensitivity and selectivity to formaldehyde. The interface between the two materials plays a significant role in enhancing sensor properties.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Analytical
Hwaebong Jung, Junho Hwang, Yong-Sahm Choe, Hyun-Sook Lee, Wooyoung Lee
Summary: This study presents a breath hydrogen analyzer based on a Pd-coated SnO2 nanorods (Pd-SnO2 NRs) sensor integrated into a miniaturized gas chromatography column. The device demonstrates the ability to accurately detect hydrogen in real-time using a small volume of breath sample. Results show that the Pd-SnO2 NRs sensor exhibits superior selectivity and sensitivity compared to other semiconducting metal oxides.
Article
Chemistry, Analytical
Sihang Lu, Yuzhu Zhang, Jingyao Liu, Hua-Yao Li, Zhixiang Hu, Xie Luo, Naibo Gao, Bao Zhang, Jianjun Jiang, Aihua Zhong, Jingting Luo, Huan Liu
Summary: Highly sensitive H-2 gas sensors based on porous network of SnO2 nanowires were demonstrated in this study, with improved performance and shortened response/recovery time after Pd doping. The superb sensitivity of the sensor was credited to the ultrathin SnO2 nanowires network structure and the catalytic activity of Pd.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Jihee Kim, Masoud Nazarian-Samani, Jihyun Lee, Sang-kil Lee, Kyu Hyong Lee, Ji Hee Pi, Yu Jin Kim, Sanghyeon Lee, Wooyoung Lee
Summary: High selectivity and fast response are crucial for protecting human health in dangerous environments. The p-n SnO/SnO2 heterostructure, with its synergistic effect on semiconducting properties and interfacial electric field, shows excellent sensing performances. It has a high response rate, fast response time, and superior selectivity compared to other target gases. The presence of oxygen vacancies in the SnO/SnO2 heterostructure is supported by Raman and EPR results, and the role of these vacancies as an effective electron donor for adsorbed oxygen molecules and NO2 target gas is described by XPS and ToF-SIMS analyses. The direct formation of oxygen vacancies in SnO/SnO2 heterostructures is an important reference for the development of high-performance NO2 gas sensors.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Nanoscience & Nanotechnology
Sukhwinder Singh, Jyotirmoy Deb, Jatinder Vir Singh, Utpal Sarkar, Sandeep Sharma
Summary: By using a heterostructure-based design with a MoSe2/SnO2 composite, sensitive and selective detection of ethyl mercaptan at room temperature has been achieved. The composite shows detection capability for ethyl mercaptan over a wider range of relative humidity and exhibits adsorption selectivity towards ethyl mercaptan compared to other analytes. The device also maintains stable response even at extreme humidity levels.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Ceramics
Xi-Tao Yin, Zhi-Yu Yang, Davoud Dastan, Ying Liu, Xiao-Ming Tan, Xiao-Chun Gao, Yan-Wen Zhou, Jing Li, Xiao-Guang Ma
Summary: In this study, Pt loaded SnO2-Co3O4 composite was successfully fabricated using a hydrothermal method and applied to gas sensing for the first time. The results showed that the composite exhibited significantly improved response and response time to hydrogen gas compared to pristine SnO2. Additionally, the material also demonstrated excellent sensing performance including selectivity for detecting H2 gas. The improved sensing properties were attributed to the synergistic effect of the spillover effect of Pt element and the formation of p-n junction.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Physical
Q. N. Abdullah, A. R. Ahmed, A. M. Ali, F. K. Yam, Z. Hassan, M. Bououdina
Summary: Nanostructured beta-Ga2O3 nanobelts were successfully fabricated using a thermal evaporation method, and a sol-gel processed SnO2 layer was deposited to modify the functionality of gallium oxide. The sensing characteristics of SnO2-functionalized beta-Ga2O3 nanobelts towards analyte gas H2 were found to be greatly improved within a certain concentration range.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Nanoscience & Nanotechnology
Xiaojie Zhu, Xueting Chang, Sikai Tang, Xiaoqiu Chen, Weixiang Gao, Shicong Niu, Junfeng Li, Yingchang Jiang, Shibin Sun
Summary: This study successfully addresses the trade-off between gas-sensing performance and anti-humidity ability of chemiresistive gas sensors by preparing hydrophobic inorganic CeO2/SnO2 heterostructure films. The sensors based on these films demonstrate excellent gas-sensing performance towards TEA and promising anti-humidity ability.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Yijun Yang, Bohee Maeng, Dong Geon Jung, Junyeop Lee, Yeongsam Kim, JinBeom Kwon, Hee Kyung An, Daewoong Jung
Summary: The study focuses on the performance of SnO2 thin film sensors for H-2 gas, revealing that annealed films exhibit higher response and shorter response time.
Article
Chemistry, Multidisciplinary
Zhenjiang Li, Min Zhang, Linyu Yang, Rong Wu, Zhaofeng Wu, Youquan Jiang, Lina Zhou, Yanan Liu
Summary: Pure zinc hydroxystannate (ZnSn(OH)(6)) and LiCl-doped ZnSn(OH)(6) were synthesized through a wet chemical method. The LiCl-doped samples showed improved humidity-sensing properties compared to the pure ZnSn(OH)(6). Specifically, the 16 wt% LiCl/ZnSn(OH)(6) exhibited higher resistive sensitivity, smaller hysteresis, and faster response speed.
Article
Chemistry, Analytical
Guodong Li, Yanbai Shen, Sikai Zhao, Ang Li, Shuling Gao, Dezhou Wei, Zhenyu Yuan, Fanli Meng, Dan Meng
Summary: This study successfully reduced the operating temperature and improved moisture resistance of H2 sensors by using PtSnx modified rGO-SnO2 nanocomposites. The nanocomposites exhibited ppm-level H2 sensing performance at 175°C and showed good moisture resistance, reproducibility, and long-term stability. The research suggests that PtSnx-rGO-SnO2 nanocomposites may be a promising material for high-performance H2 detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Chengming Lou, Zishuo Li, Chen Yang, Xianghong Liu, Wei Zheng, Jun Zhang
Summary: A highly selective and humidity-resistant gas sensor based on SnO2/ZrO2 porous thin films with a three-dimensionally ordered microstructure (3DOM) has been developed, showing decent response to triethylamine (TEA) with ultrafast response and recovery speed. The sensor also exhibits superior selectivity, long-time stability and a low detection limit, making it potentially useful for practical TEA detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Wei Wang, Qinyi Zhang, Ruonan Lv, Dong Wu, Shunping Zhang
Summary: This study successfully enhanced the selectivity to formaldehyde by modifying the surface of metal oxide semiconductors with a zeolite layer, and controlled the thickness of the layer to achieve outstanding performance.
Article
Chemistry, Physical
Aifa Sun, Huimin Yu, Yue Zhou, Yangquan Liu, Jingting Luo, Ping Fan, Aihua Zhong
Summary: A Pd gated HEMT device with high sensitivity to low concentrations of hydrogen gas was demonstrated, showing fast response and short response/recovery times, while having no response to certain gases and enhanced sensing performance under light illumination.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
Article
Nanoscience & Nanotechnology
Syrine Behi, Juan Casanova-Chafer, Ernesto Gonzalez, Nadra Bohli, Eduard Llobet, Adnane Abdelghani
Summary: This paper presents a four-sensor array with different nano-carbon sensitive layers for sensitive detection of various gas species. Through characterization and extensive experimental study, the sensing mechanism is revealed and a model for target gas identification and concentration prediction is developed.
Article
Polymer Science
Alain Pauly, Sahal Saad Ali, Christelle Varenne, Jerome Brunet, Eduard Llobet, Amadou L. Ndiaye
Summary: In this study, we synthesized a composite nanostructure PANI/MCs by combining a conducting polymer, polyaniline (PANI), with an organic semiconducting macrocyclic (MCs) material. The resulting composite nanostructure showed good electrical properties and enhanced sensing performance. Furthermore, the sensing behavior under different conditions, including ambient humidity and temperature, was investigated, revealing unique characteristics that contribute to understanding the sensing mechanism.
Article
Chemistry, Analytical
Ghada El Fidha, Nabila Bitri, Sarra Mahjoubi, Fatma Chaabouni, Eduard Llobet, Juan Casanova-Chafer
Summary: Pure and dysprosium-loaded ZnO films were grown and characterized. The study showed that ZnO sensors doped with rare-earth materials exhibit improved sensitivity and stability in detecting nitrogen dioxide at ppb levels.
Article
Chemistry, Analytical
N. Sola-Penaftel, X. Manyosa, E. Navarrete, J. Ramos-Castro, V. Jimenez, S. Bermejo, I. Gracia, E. Llobet, M. Dominguez-Pumar
Summary: The objective of this study is to improve the response time of MOX gas sensors by applying a closed-loop control based on dielectric excitation. This control method implements a feedback loop that keeps the sensor reactance constant by modulating the temperature. The required fast temperature switching is achieved on MEMS microhotplates.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Materials Science, Multidisciplinary
Kirill Kamnev, Zdenek Pytlicek, Maria Bendova, Jan Prasek, Francesc Gispert-Guirado, Eduard Llobet, Alexander Mozalev
Summary: The demand for integrated passive devices (IPDs) arises from the increasing consumer demand for miniaturization of electronic products. Metal-insulator-metal (MIM) capacitors are essential components of IPD systems. Developing new materials and technologies is crucial for enhancing capacitor characteristics and co-integration with other electronic passives.
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Liliana Margarita Garciia Rojas, Carlos Alberto Huerta-Aguilar, Eric Navarrete, Eduard Llobet, Pandiyan Thangarasu
Summary: This study investigates the doping of cations on ZrO2 for the adsorption of CO2. The deposition of metal ions on ZrO2 leads to the transformation of crystalline phases and thermal stability of the samples. The experimental results show that CoZrO2 exhibits the highest CO2 capture capacity of approximately 75%.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Physical
Khaoula Kacem, Juan Casanova-Chafer, Sami Ameur, Mohamed Faouzi Nsib, Eduard Llobet
Summary: This paper presents a simple and low-cost method for fabricating gas sensing devices using graphene oxide (GO) decorated with strontium titanate perovskite (SrTiO3). The active layers developed were capable of detecting hazardous gases such as NO2, CO2, and NH3 with high sensitivity and selectivity. The physical and chemical properties of the materials were analyzed using various experimental techniques, and a gas sensing mechanism was proposed and discussed. These findings demonstrate that functionalizing GO with SrTiO3 can enhance the adsorption capability and sensitivity of GO-based gas sensors.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Chemistry, Analytical
Tomoya Minezaki, Peter Kruger, Fatima Ezahra Annanouch, Juan Casanova-Chafer, Aanchal Alagh, Ignacio J. J. Villar-Garcia, Virginia Perez-Dieste, Eduard Llobet, Carla Bittencourt
Summary: This study investigates the hydrogen sensing mechanism of a nanostructured WS2 layer using NAP-XPS and DFT. The results suggest that hydrogen physisorbs on the WS2 active surface at room temperature and chemisorbs on tungsten atoms at higher temperatures. DFT calculations show that hydrogen adsorbs physically on the defect-free WS2 monolayer, but forms chemical bonds with tungsten atoms on sulfur defects. The hydrogen adsorption causes charge transfer and reduces the intensity of in-gap states, leading to an increase in the gas sensor resistance.
Article
Chemistry, Analytical
Omar Zaim, Benachir Bouchikhi, Soukaina Motia, Sonia Abello, Eduard Llobet, Nezha El Bari
Summary: Studies suggest that breath and urine analysis can be viable non-invasive methods for diabetes management and diagnosis. This study used two sensing strategies, analyzing VOCs in biological matrices and using data fusion to discriminate between types of diabetes. The results showed that an electronic nose and voltametric electronic tongue had high success rates for discriminating between breath and urine samples of diabetes patients and healthy controls. However, data fusion was necessary to improve the discrimination between type 1 and type 2 diabetes samples, resulting in an enhanced success rate of classification.
Article
Chemistry, Analytical
Selene Acosta, Juan Casanova-Chafer, Eduard Llobet, Axel Hemberg, Mildred Quintana, Carla Bittencourt
Summary: The properties of carbon nanotubes can be modified by adding metal nanoparticles to their surface. This is achieved by first functionalizing the CNTs with oxygen groups using plasma, followed by decorating them with Ni-Pd bimetallic nanoparticles using plasma sputtering deposition. The oxygen groups act as nucleation sites for the growth of the bimetallic nanoparticles. The resulting Ni-Pd nanoparticle-decorated CNTs are then evaluated for their sensing capabilities in detecting toluene.
Article
Chemistry, Analytical
Shuja Bashir Malik, Fatima Ezahra Annanouch, Eduard Llobet
Summary: Efficient hydrogen gas sensors based on multilayered p-type bare MoS2 and Pd-decorated MoS2 were successfully fabricated and characterized. The addition of Pd nanoparticles increased the sensitivity of the sensors, and a slight increase in response was observed when exposed to humidity.
Article
Engineering, Electrical & Electronic
Juan Casanova-Chafer, Xavier Blanch, Eduard Llobet
Summary: This study presents a gas sensor based on graphene decorated with polypyrrole nanoparticles for the detection of dimethyl methylphosphonate (DMMP), a chemical warfare agent simulant. The sensor exhibits high stability and reversible interaction with DMMP at ambient temperature, showing a linear response to different concentrations of DMMP with a sensitivity of 14.2% per ppm. The sensor's potential for sensitive trace level detection of DMMP in real-world applications is attributed to the synergistic effect between graphene and polypyrrole nanoparticles.
IEEE SENSORS LETTERS
(2023)
Article
Chemistry, Multidisciplinary
M. Mezyen, G. El Fidha, N. Bitri, F. Harrathi, I. Ly, E. Llobet
Summary: This paper explores the impact of dysprosium (Dy) doping on the structural, optical, and photocatalytic properties of tin oxide (SnO2) thin films. The results show that dysprosium doping can improve the crystalline quality and film quality, and can also change the crystal orientation. Additionally, dysprosium doping leads to the formation of numerous micro-aggregates on the film's surface. Importantly, SnO2:Dy 5% thin films exhibit high degradation efficiency under solar irradiation.
Proceedings Paper
Chemistry, Analytical
Marta Padilla, Moritz Kleinstrab, Miguel Angel Leon, Ernesto Gonzalez, Manuel Sparano, Marina Ribas, Ainhoa Rezola, Andoni Beriain, Eduard Llobet, Jan Mitrovics
Summary: The SENSOFT project combines various technologies to create a low-cost, low-power, reliable, and highly sensitive gas sensing network for early warning of chemical threats detection.
2022 IEEE INTERNATIONAL SYMPOSIUM ON OLFACTION AND ELECTRONIC NOSE (ISOEN 2022)
(2022)
Article
Materials Science, Multidisciplinary
Fatima Ezahra Annanouch, Aanchal Alagh, Polona Umek, Juan Casanova-Chafer, Carla Bittencourt, Eduard Llobet
Summary: By adjusting the gas flow rate, controlled growth of edge enriched 3D assemblies of MoS2 nanosheets was achieved, showcasing high sensitivity to NH3 and NO2 as well as low humidity cross-sensitivity.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
