Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum

Lipopolysaccharide Is a Direct Agonist for Platelet RNA Splicing

(2014) P. N. Shashkin et al.   JOURNAL OF IMMUNOLOGY

The septic milieu triggers expression of spliced tissue factor mRNA in human platelets

(2011) M. T. RONDINA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Staphylococcus aureus α-Toxin Triggers the Synthesis of B-Cell Lymphoma 3 by Human Platelets

(2011) Sebastian Schubert et al.   Toxins

The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses

(2010) Christian C. Yost et al.   BIOCHIMIE

Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation

(2010) P. Uhrin et al.   BLOOD

Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice

(2010) R. Pawlinski et al.   BLOOD

Anucleate platelets generate progeny

(2010) H. Schwertz et al.   BLOOD

Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling

(2010) C. C. Bertozzi et al.   BLOOD

Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease

(2010) C. Lood et al.   BLOOD

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Lymphangiogenesis: Molecular Mechanisms and Future Promise

(2010) Tuomas Tammela et al.   CELL

Immunogenicity of Whole-Parasite Vaccines against Plasmodium falciparum Involves Malarial Hemozoin and Host TLR9

(2010) Cevayir Coban et al.   Cell Host & Microbe

Relation of Platelet and Leukocyte Inflammatory Transcripts to Body Mass Index in the Framingham Heart Study

(2010) Jane E. Freedman et al.   CIRCULATION

Clinical relevance of microparticles from platelets and megakaryocytes

(2010) Joseph E Italiano et al.   CURRENT OPINION IN HEMATOLOGY

Platelets: versatile modifiers of innate and adaptive immune responses to transplants

(2010) William M Baldwin et al.   Current Opinion in Organ Transplantation

Platelet Tissue Factor Synthesis in Type 2 Diabetic Patients Is Resistant to Inhibition by Insulin

(2010) A. J. Gerrits et al.   DIABETES

Effects of platelet activating factor (PAF) on human citrated whole blood

(2010) P. Groscurth et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

Circulating platelet-neutrophil complexes are important for subsequent neutrophil activation and migration

(2010) Kristin N. Kornerup et al.   JOURNAL OF APPLIED PHYSIOLOGY

Essentialin VivoRoles of the C-type Lectin Receptor CLEC-2

(2010) Katsue Suzuki-Inoue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function

(2010) Hervé Falet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CXC Chemokine Ligand 4 Induces a Unique Transcriptome in Monocyte-Derived Macrophages

(2010) C. A. Gleissner et al.   JOURNAL OF IMMUNOLOGY

Prostaglandin E2 Differentially Modulates Human Platelet Function through the Prostanoid EP2 and EP3 Receptors

(2010) G. Petrucci et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Complement activation on platelets: Implications for vascular inflammation and thrombosis

(2010) Ellinor I. Peerschke et al.   MOLECULAR IMMUNOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

(2010) Steffen Massberg et al.   NATURE MEDICINE

Platelet Factor 4 Regulation of Monocyte KLF4 in Experimental Cerebral Malaria

(2010) Kalyan Srivastava et al.   PLoS One

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognizing the First Responders

(2010) K. L. Mueller   SCIENCE

Arsonists in Rheumatoid Arthritis

(2010) G. A. Zimmerman et al.   SCIENCE

Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production

(2010) E. Boilard et al.   SCIENCE

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Nuclear Emancipation: A Platelet Tour de Force

(2010) S. L. Spinelli et al.   Science Signaling

Targeting Robo4-Dependent Slit Signaling to Survive the Cytokine Storm in Sepsis and Influenza

(2010) N. R. London et al.   Science Translational Medicine

Safety and Antithrombotic Efficacy of Moderate Platelet Count Reduction by Thrombopoietin Inhibition in Primates

(2010) E. I. Tucker et al.   Science Translational Medicine

Platelet CD154 Potentiates Interferon-  Secretion by Plasmacytoid Dendritic Cells in Systemic Lupus Erythematosus

(2010) P. Duffau et al.   Science Translational Medicine

The Role of Platelets in Liver Inflammation and Regeneration

(2010) Ton Lisman et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Platelets as immune mediators: Their role in host defense responses and sepsis

(2010) Zhenyu Li et al.   THROMBOSIS RESEARCH

Platelets as initiators and mediators of inflammation at the vessel wall

(2010) Guanfang Shi et al.   THROMBOSIS RESEARCH

Platelets Control Leukocyte Recruitment in a Murine Model of Cutaneous Arthus Reaction

(2009) Toshihide Hara et al.   AMERICAN JOURNAL OF PATHOLOGY

Sepsis Alters the Megakaryocyte–Platelet Transcriptional Axis Resulting in Granzyme B–mediated Lymphotoxicity

(2009) Robert J. Freishtat et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The blood platelets contribution to innate host defense - What they have learned from their big brothers

(2009) Dorit M. W. Zander et al.   Biotechnology Journal

Comparative genomics: fishing nets hemostatic catch

(2009) Andrew S. Weyrich et al.   BLOOD

LAD syndromes: FERMT3 kindles the signal: Figure 1

(2009) Guy A. Zimmerman   BLOOD

Class prediction models of thrombocytosis using genetic biomarkers

(2009) D. V. Gnatenko et al.   BLOOD

Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates

(2009) C. C. Yost et al.   BLOOD

A HaemAtlas: characterizing gene expression in differentiated human blood cells

(2009) Nicholas A. Watkins et al.   BLOOD

The role of platelets in the pathogenesis of cerebral malaria

(2009) Dermot Cox et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Platelets in defense against bacterial pathogens

(2009) Michael R. Yeaman   CELLULAR AND MOLECULAR LIFE SCIENCES

Platelets and innate immunity

(2009) John W. Semple et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Platelet receptors and signaling in the dynamics of thrombus formation

(2009) J. Rivera et al.   HAEMATOLOGICA

The platelet as an immune cell—CD40 ligand and transfusion immunomodulation

(2009) Neil Blumberg et al.   IMMUNOLOGIC RESEARCH

TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans

(2009) A. Valance Washington et al.   JOURNAL OF CLINICAL INVESTIGATION

The Unexpected Pleiotropic Activities of RANTES

(2009) J. A. Levy   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide Stimulates Platelet Secretion and Potentiates Platelet Aggregation via TLR4/MyD88 and the cGMP-Dependent Protein Kinase Pathway

(2009) G. Zhang et al.   JOURNAL OF IMMUNOLOGY

PSGL-1-dependent myeloid leukocyte activation

(2009) Alexander Zarbock et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Heparin-induced thrombocytopenia

(2009) A. GREINACHER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet functions beyond hemostasis

(2009) S. S. SMYTH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Protein synthesis by platelets: historical and new perspectives

(2009) A. S. WEYRICH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Existence of a microRNA pathway in anucleate platelets

(2009) Patricia Landry et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Platelets Kill Intraerythrocytic Malarial Parasites and Mediate Survival to Infection

(2009) B. J. McMorran et al.   SCIENCE

Effect of antiplatelet therapy on inflammatory markers in atherothrombotic patients

(2009) J. B. Muhlestein   THROMBOSIS AND HAEMOSTASIS

NETs: a new strategy for using old weapons

(2009) Venizelos Papayannopoulos et al.   TRENDS IN IMMUNOLOGY

Amicus or Adversary

(2008) Fernando A. Bozza et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Tissue Factor in Patients With Acute Coronary Syndromes

(2008) Marta Brambilla et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Novel Therapeutic Targets at the Platelet Vascular Interface

(2008) Lawrence F. Brass et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Signal-Dependent Protein Synthesis by Activated Platelets

(2008) Guy A. Zimmerman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

P2Y 12 Antagonism

(2008) Alan D. Michelson   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

G-Protein–Coupled Receptors as Signaling Targets for Antiplatelet Therapy

(2008) Susan S. Smyth et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

(2008) Marie N. O'Connor et al.   BLOOD

Platelet-mediated modulation of adaptive immunity: unique delivery of CD154 signal by platelet-derived membrane vesicles

(2008) D. L. Sprague et al.   BLOOD

Platelet-derived CD154 enables T-cell priming and protection against Listeria monocytogenes challenge

(2008) B. D. Elzey et al.   BLOOD

Inflammation induces hemorrhage in thrombocytopenia

(2008) T. Goerge et al.   BLOOD

The GPIIb/IIIa (integrin  IIb 3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend

(2008) B. S. Coller et al.   BLOOD

Reduced thrombin generation increases host susceptibility to group A streptococcal infection

(2008) H. Sun et al.   BLOOD

Direct contact of platelets and their released products exert different effects on human dendritic cell maturation

(2008) Hind Hamzeh-Cognasse et al.   BMC IMMUNOLOGY

Fibronectin bridges monocytes and reticulocytes via integrin α4β1

(2008) Julia E. Brittain et al.   BRITISH JOURNAL OF HAEMATOLOGY

Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human platelets

(2008) Fabrice Cognasse et al.   BRITISH JOURNAL OF HAEMATOLOGY

Platelet Factor 4 Mediates Inflammation in Experimental Cerebral Malaria

(2008) Kalyan Srivastava et al.   Cell Host & Microbe

Stimulation of Toll-Like Receptor 2 in Human Platelets Induces a Thromboinflammatory Response Through Activation of Phosphoinositide 3-Kinase

(2008) Price Blair et al.   CIRCULATION RESEARCH

Platelets and HIV-1 Infection: Old and New Aspects

(2008) Donato Torre et al.   CURRENT HIV RESEARCH

Imaging the interaction between dengue 2 virus and human blood platelets using atomic force and electron microscopy

(2008) K. Ghosh et al.   Microscopy

Platelet-lymphocyte cross-talk

(2008) Nailin Li   JOURNAL OF LEUKOCYTE BIOLOGY

Functional expression of IgA receptor FcαRI on human platelets

(2008) Kun Qian et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases

(2008) J. M. van Gils et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tissue factor and IL8 production by P-selectin-dependent platelet–monocyte aggregates in whole blood involves phosphorylation of Lyn and is inhibited by IL10

(2008) C. CHRISTERSSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The influence of platelet activating factor on the effects of platelet agonists and antiplatelet agents in vitro

(2008) Friederike K. Keating et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Triggers, targets and treatments for thrombosis

(2008) Nigel Mackman   NATURE

Aggravation of viral hepatitis by platelet-derived serotonin

(2008) Philipp A Lang et al.   NATURE MEDICINE

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Platelets prevent IFN- / -induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus

(2008) M. Iannacone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ETosis: A Novel Cell Death Pathway

(2008) F. Wartha et al.   Science Signaling

Tissue factor storage, synthesis and function in normal and activated human platelets

(2008) Diego Mezzano et al.   THROMBOSIS RESEARCH

Induction of platelet white blood cell (WBC) aggregate formation by platelets and WBCs in red blood cell units

(2008) Friederike K. Keating et al.   TRANSFUSION