A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism

Serum and Glucocorticoid-Regulated Kinase 1 Regulates Neutrophil Clearance during Inflammation Resolution

(2014) J. Burgon et al.   JOURNAL OF IMMUNOLOGY

Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents

(2013) Jesmond Dalli et al.   CHEMISTRY & BIOLOGY

Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library

(2013) X. Wang et al.   Disease Models & Mechanisms

Retrotaxis of human neutrophils during mechanical confinement inside microfluidic channels

(2013) Bashar Hamza et al.   Integrative Biology

Repelled from the wound, or randomly dispersed? Reverse migration behaviour of neutrophils characterized by dynamic modelling

(2012) G. R. Holmes et al.   Journal of the Royal Society Interface

Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury

(2012) O Eickmeier et al.   Mucosal Immunology

Tanshinone IIA Attenuates the Inflammatory Response and Apoptosis after Traumatic Injury of the Spinal Cord in Adult Rats

(2012) Xin Yin et al.   PLoS One

Activation of hypoxia-inducible factor-1  (Hif-1 ) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model

(2011) P. M. Elks et al.   BLOOD

A high-throughput chemically induced inflammation assay in zebrafish

(2011) Claudia A d'Alençon et al.   BMC BIOLOGY

Spatiotemporal photolabeling of neutrophil trafficking during inflammation in live zebrafish

(2011) S. K. Yoo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Chemical informatics and target identification in a zebrafish phenotypic screen

(2011) Christian Laggner et al.   Nature Chemical Biology

The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo

(2011) Abigail Woodfin et al.   NATURE IMMUNOLOGY

Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation

(2011) David J. Wardle et al.   PLoS One

Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: Does variable inhibition of interleukin-6 production limit effectiveness in vivo?

(2010) Theresa H. Page et al.   ARTHRITIS AND RHEUMATISM

The cyclin-dependent kinase inhibitor R-roscovitine down-regulates Mcl-1 to override pro-inflammatory signalling and drive neutrophil apoptosis

(2010) Andrew E. Leitch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-1β induces ICAM-1 expression enhancing leukocyte adhesion in human rheumatoid arthritis synovial fibroblasts: Involvement of ERK, JNK, AP-1, and NF-κB

(2010) Chuen-Mao Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neutrophil Apoptosis: Relevance to the Innate Immune Response and Inflammatory Disease

(2010) Sarah Fox et al.   Journal of Innate Immunity

Resolvins: Natural agonists for resolution of pulmonary inflammation

(2010) Mohib Uddin et al.   PROGRESS IN LIPID RESEARCH

Tanshinone IIA reduces lethality and acute lung injury in LPS-treated mice by inhibition of PLA2 activity

(2009) Min Xu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish

(2009) Catherine A. Loynes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inhibition of prostaglandin and nitric oxide production in lipopolysaccharide-treated RAW 264.7 cells by tanshinones from the roots of Salvia miltiorrhiza bunge

(2008) Su Jin Jeon et al.   ARCHIVES OF PHARMACAL RESEARCH

Flagellin and lipopolysaccharide up-regulation of IL-6 and CXCLi2 gene expression in chicken heterophils is mediated by ERK1/2-dependent activation of AP-1 and NF-κB signaling pathways

(2008) Michael H. Kogut et al.   Innate Immunity

Inhibition of Lipopolysaccharide-Stimulated Chronic Obstructive Pulmonary Disease Macrophage Inflammatory Gene Expression by Dexamethasone and the p38 Mitogen-Activated Protein Kinase Inhibitor N-cyano-N'-(2-{[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7-oxo-7,8-dihydropyrido[2,3-d] pyrimidin-2-yl]amino}ethyl)guanidine (SB706504)

(2008) L. M. Kent et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Approximate Bayesian computation scheme for parameter inference and model selection in dynamical systems

(2008) T. Toni et al.   Journal of the Royal Society Interface

Novel pharmacological strategies for driving inflammatory cell apoptosis and enhancing the resolution of inflammation

(2008) John M. Hallett et al.   TRENDS IN PHARMACOLOGICAL SCIENCES