Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin

Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents

(2015) Thomas Reiner et al.   NEOPLASIA

HIF-1α Inhibition Reverses Multidrug Resistance in Colon Cancer Cells via Downregulation of MDR1/P-Glycoprotein

(2014) Jianfang Chen et al.   PLoS One

Evolving Approaches to Metastatic Breast Cancer Patients Pre-treated with Anthracycline and Taxane

(2013) Shigehira Saji   BIODRUGS

P-glycoprotein Inhibition as a Therapeutic Approach for Overcoming Multidrug Resistance in Cancer: Current Status and Future Perspectives

(2013) Ziyad Binkhathlan et al.   CURRENT CANCER DRUG TARGETS

Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles

(2013) N. Kamaly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo

(2013) Greg M. Thurber et al.   Nature Communications

Engineering Particles for Therapeutic Delivery: Prospects and Challenges

(2012) Yan Yan et al.   ACS Nano

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

(2012) Nazila Kamaly et al.   CHEMICAL SOCIETY REVIEWS

Tolerability and Pharmacokinetics of a New P-Glycoprotein Inhibitor, HM30181, in Healthy Korean Male Volunteers: Single- and Multiple-Dose Randomized, Placebo-Controlled Studies

(2012) Tae-Eun Kim et al.   CLINICAL THERAPEUTICS

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

(2012) Luis A. Diaz Jr et al.   NATURE

Intravital Imaging

(2011) Mikael J. Pittet et al.   CELL

Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor

(2011) Marc Vendrell et al.   CHEMICAL COMMUNICATIONS

Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study

(2011) Javier Cortes et al.   LANCET

Expression and significance of hypoxia-inducible factor-1 alpha and MDR1/P-glycoprotein in human colon carcinoma tissue and cells

(2010) Zhenyu Ding et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

In Vivo Imaging in Cancer

(2010) J. Condeelis et al.   Cold Spring Harbor Perspectives in Biology

Selective inhibition of MDR1 (ABCB1) by HM30181 increases oral bioavailability and therapeutic efficacy of paclitaxel

(2009) Jin-Oh Kwak et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis

(2009) Lavinia Nardinocchi et al.   Molecular Cancer

Automatic Segmentation of High-Throughput RNAi Fluorescent Cellular Images

(2008) Pingkun Yan et al.   IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE

Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase

(2008) T. Okouneva et al.   MOLECULAR CANCER THERAPEUTICS

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

(2008) S. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA