Familial Hypercholesterolemia and Atherosclerosis in Cloned Minipigs Created by DNA Transposition of a Human PCSK9 Gain-of-Function Mutant
出版年份 2013 全文链接
标题
Familial Hypercholesterolemia and Atherosclerosis in Cloned Minipigs Created by DNA Transposition of a Human PCSK9 Gain-of-Function Mutant
作者
关键词
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出版物
Science Translational Medicine
Volume 5, Issue 166, Pages 166ra1-166ra1
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2013-01-03
DOI
10.1126/scitranslmed.3004853
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect
- (2011) Dallit Mannheim et al. ATHEROSCLEROSIS
- Unexpected roles for PCSK9 in lipid metabolism
- (2011) Anne K Soutar CURRENT OPINION IN LIPIDOLOGY
- Why not screen for subclinical atherosclerosis?
- (2011) Henrik Sillesen et al. LANCET
- Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial
- (2011) Zahi A Fayad et al. LANCET
- Progress and challenges in translating the biology of atherosclerosis
- (2011) Peter Libby et al. NATURE
- A Prospective Natural-History Study of Coronary Atherosclerosis
- (2011) Gregg W. Stone et al. NEW ENGLAND JOURNAL OF MEDICINE
- Atherosclerosis Drug Development in Jeopardy: The Need for Predictive Biomarkers of Treatment Response
- (2011) D. A. Fryburg et al. Science Translational Medicine
- Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system
- (2011) Daniel F. Carlson et al. TRANSGENIC RESEARCH
- Swine as Models in Biomedical Research and Toxicology Testing
- (2011) M. M. Swindle et al. VETERINARY PATHOLOGY
- ApoE-Deficient Mice on Cholate-Containing High-Fat Diet Reveal a Pathology Similar to Lung Sarcoidosis
- (2010) Andriy O. Samokhin et al. AMERICAN JOURNAL OF PATHOLOGY
- Increased Secretion of Lipoproteins in Transgenic Mice Expressing Human D374Y PCSK9 Under Physiological Genetic Control
- (2010) Bronwen Herbert et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Pig genome sequence - analysis and publication strategy
- (2010) Alan L Archibald et al. BMC GENOMICS
- Intracoronary Optical Coherence Tomography and Histology at 1 Month and 2, 3, and 4 Years After Implantation of Everolimus-Eluting Bioresorbable Vascular Scaffolds in a Porcine Coronary Artery Model
- (2010) Yoshinobu Onuma et al. CIRCULATION
- Unreliable Assessment of Necrotic Core by Virtual Histology Intravascular Ultrasound in Porcine Coronary Artery Disease
- (2010) Troels Thim et al. Circulation-Cardiovascular Imaging
- Atherosclerotic lesions in mouse and man: is it the same disease?
- (2010) Jacob Fog Bentzon et al. CURRENT OPINION IN LIPIDOLOGY
- Pregnancies and piglets from large white sow recipients after two transfer methods of cloned and transgenic embryos of different pig breeds
- (2010) M. Schmidt et al. THERIOGENOLOGY
- Pig transgenesis by Sleeping Beauty DNA transposition
- (2010) Jannik E. Jakobsen et al. TRANSGENIC RESEARCH
- Porcine models of coronary atherosclerosis and vulnerable plaque for imaging and interventional research
- (2010) Juan Granada et al. EuroIntervention
- Familial hypercholesterolaemic downsized pig with human-like coronary atherosclerosis: a model for preclinical studies
- (2010) Troels Thim et al. EuroIntervention
- Genetic and Metabolic Determinants of Plasma PCSK9 Levels
- (2009) Susan G. Lakoski et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The unique role of proprotein convertase subtilisin/kexin 9 in cholesterol homeostasis
- (2009) S. A. Mousavi et al. JOURNAL OF INTERNAL MEDICINE
- Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates
- (2009) Lajos Mátés et al. NATURE GENETICS
- Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer’s disease-causing dominant mutation APPsw
- (2009) Peter M. Kragh et al. TRANSGENIC RESEARCH
- Evidence Mandating Earlier and More Aggressive Treatment of Hypercholesterolemia
- (2008) Daniel Steinberg et al. CIRCULATION
- Drug-Eluting Stents in Preclinical Studies
- (2008) Robert S. Schwartz et al. Circulation-Cardiovascular Interventions
- Atherosclerosis Inflammation Imaging with 18F-FDG PET: Carotid, Iliac, and Femoral Uptake Reproducibility, Quantification Methods, and Recommendations
- (2008) J. H.F. Rudd et al. JOURNAL OF NUCLEAR MEDICINE
- Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
- (2008) Robert L Wilensky et al. NATURE MEDICINE
- Targeting bile-acid signalling for metabolic diseases
- (2008) Charles Thomas et al. NATURE REVIEWS DRUG DISCOVERY
- Molecular basis for LDL receptor recognition by PCSK9
- (2008) H. J. Kwon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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