PLC , PKD1, and SSH1L Transduce RhoA Signaling to Protect Mitochondria from Oxidative Stress in the Heart

Phospholipase Cε Hydrolyzes Perinuclear Phosphatidylinositol 4-Phosphate to Regulate Cardiac Hypertrophy

(2013) Lianghui Zhang et al.   CELL

Phospholipase Cɛ links G protein-coupled receptor activation to inflammatory astrocytic responses

(2013) Stephanie S. Dusaban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysophospholipid receptor activation of RhoA and lipid signaling pathways

(2012) Sunny Yang Xiang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Role of phospholipase Cε in physiological phosphoinositide signaling networks

(2012) Alan V. Smrcka et al.   CELLULAR SIGNALLING

Bax regulates primary necrosis through mitochondrial dynamics

(2012) R. S. Whelan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein kinase D: coupling extracellular stimuli to the regulation of cell physiology

(2011) Ya Fu et al.   EMBO REPORTS

Protein Kinase D Regulates Cofilin Activity through p21-activated Kinase 4

(2011) Samantha J. Spratley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RhoA protects the mouse heart against ischemia/reperfusion injury

(2011) Sunny Yang Xiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death

(2011) Inmaculada Posadas et al.   JOURNAL OF NEUROCHEMISTRY

Protein Kinase D Signaling: Multiple Biological Functions in Health and Disease

(2011) Enrique Rozengurt   PHYSIOLOGY

BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore

(2011) Loren D. Walensky et al.   TRENDS IN BIOCHEMICAL SCIENCES

Methyl Antcinate A fromAntrodia camphorataInduces Apoptosis in Human Liver Cancer Cells through Oxidant-Mediated Cofilin- and Bax-Triggered Mitochondrial Pathway

(2010) Yun-Chih Hsieh et al.   CHEMICAL RESEARCH IN TOXICOLOGY

PHLPP-1 Negatively Regulates Akt Activity and Survival in the Heart

(2010) Shigeki Miyamoto et al.   CIRCULATION RESEARCH

Loss of Enigma Homolog Protein Results in Dilated Cardiomyopathy

(2010) Hongqiang Cheng et al.   CIRCULATION RESEARCH

Constitutively active Protein kinase D acts as negative regulator of the Slingshot-phosphatase in Drosophila

(2010) Anja C. Nagel et al.   HEREDITAS

Mitochondrial translocation of oxidized cofilin induces caspase-independent necrotic-like programmed cell death of T cells

(2010) G H Wabnitz et al.   Cell Death & Disease

Revisited and Revised: Is RhoA Always a Villain in Cardiac Pathophysiology?

(2010) Shigeki Miyamoto et al.   Journal of Cardiovascular Translational Research

Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning

(2009) Donald A. Vessey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Protein Kinase D Regulates Cell Migration by Direct Phosphorylation of the Cofilin Phosphatase Slingshot 1 Like

(2009) P. Peterburs et al.   CANCER RESEARCH

Cardiomyocyte S1P1 Receptor-mediated Extracellular Signal-related Kinase Signaling and Desensitization

(2009) Rong Tao et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Mitochondrial diacylglycerol initiates protein-kinase-D1-mediated ROS signaling

(2009) C. F. Cowell et al.   JOURNAL OF CELL SCIENCE

Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum

(2009) S. Lange et al.   JOURNAL OF CELL SCIENCE

Loss of cell-cell contacts induces NF-κB via RhoA-mediated activation of protein kinase D1

(2009) Catherine F. Cowell et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Activation of the protective Survivor Activating Factor Enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway?

(2009) Sandrine Lecour   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin

(2009) Fábio Klamt et al.   NATURE CELL BIOLOGY

Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot

(2009) Tim Eiseler et al.   NATURE CELL BIOLOGY

Targeted Inhibition of Cardiomyocyte Gi Signaling Enhances Susceptibility to Apoptotic Cell Death in Response to Ischemic Stress

(2008) Brent R. DeGeorge et al.   CIRCULATION

Sphingosine can pre- and post-condition heart and utilizes a different mechanism from sphingosine 1-phosphate

(2008) Donald A. Vessey et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Cysteine 62 of Bax Is Critical for Its Conformational Activation and Its Proapoptotic Activity in Response to H2O2-induced Apoptosis

(2008) Chunlai Nie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Focal Adhesion Kinase as a RhoA-activable Signaling Scaffold Mediating Akt Activation and Cardiomyocyte Protection

(2008) Dominic P. Del Re et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury

(2008) Elizabeth Murphy et al.   PHYSIOLOGICAL REVIEWS

Requirement of protein kinase D1 for pathological cardiac remodeling

(2008) J. Fielitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA