Opening and Closing of the Bacterial RNA Polymerase Clamp

New target for inhibition of bacterial RNA polymerase: ‘switch region’

(2011) Aashish Srivastava et al.   CURRENT OPINION IN MICROBIOLOGY

MATCH: An atom-typing toolset for molecular mechanics force fields

(2011) Joseph D. Yesselman et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Molecular Mechanism of Transcription Inhibition by Phage T7 gp2 Protein

(2011) Vladimir Mekler et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanism of Bacterial Transcription Initiation: RNA Polymerase - Promoter Binding, Isomerization to Initiation-Competent Open Complexes, and Initiation of RNA Synthesis

(2011) Ruth M. Saecker et al.   JOURNAL OF MOLECULAR BIOLOGY

Competing for the Clamp: Promoting RNA Polymerase Processivity and Managing the Transition from Initiation to Elongation

(2011) Grant A. Hartzog et al.   MOLECULAR CELL

Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein

(2010) Shunsuke Tagami et al.   NATURE

A prehydrolysis state of an AAA+ ATPase supports transcription activation of an enhancer-dependent RNA polymerase

(2010) P. C. Burrows et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T7 phage protein Gp2 inhibits the Escherichia coli RNA polymerase by antagonizing stable DNA strand separation near the transcription start site

(2010) B. Camara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engagement of Arginine Finger to ATP Triggers Large Conformational Changes in NtrC1 AAA+ ATPase for Remodeling Bacterial RNA Polymerase

(2010) Baoyu Chen et al.   STRUCTURE

Complete Structural Model of Escherichia coli RNA Polymerase from a Hybrid Approach

(2010) Natacha Opalka et al.   PLOS BIOLOGY

Bacterial RNA Polymerase Inhibitors: An Organized Overview of their Structure, Derivatives, Biological Activity and Current Clinical Development Status

(2009) R. Mariani et al.   CURRENT MEDICINAL CHEMISTRY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Three-dimensional EM structure of an intact activator-dependent transcription initiation complex

(2009) B. P. Hudson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RNA Polymerase “Switch Region” Is a Target for Inhibitors

(2008) Jayanta Mukhopadhyay et al.   CELL

Transcription inactivation through local refolding of the RNA polymerase structure

(2008) Georgiy A. Belogurov et al.   NATURE