Generation and study of the strains of streptomycetes-heterologous hosts for the production of moenomycin

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

(2012) Kozo Ochi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes

(2011) Steven T Pullan et al.   BMC GENOMICS

Strain improvement in actinomycetes in the postgenomic era

(2011) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Negative Epistasis Between Beneficial Mutations in an Evolving Bacterial Population

(2011) A. I. Khan et al.   SCIENCE

Diminishing Returns Epistasis Among Beneficial Mutations Decelerates Adaptation

(2011) H.-H. Chou et al.   SCIENCE

Nosokomycins, new antibiotics discovered in an in vivo-mimic infection model using silkworm larvae. I: Fermentation, isolation and biological properties

(2010) Ryuji Uchida et al.   JOURNAL OF ANTIBIOTICS

Genetic factors that influence moenomycin production in streptomycetes

(2010) Roman Makitrynskyy et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

(2010) Bohdan Ostash et al.   NATURAL PRODUCT REPORTS

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters

(2010) Juan Pablo Gomez-Escribano et al.   Microbial Biotechnology

Complete Characterization of the Seventeen Step Moenomycin Biosynthetic Pathway

(2009) Bohdan Ostash et al.   BIOCHEMISTRY

Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids

(2009) Bohdan Ostash et al.   PLASMID

Dramatic Activation of Antibiotic Production in Streptomyces coelicolor by Cumulative Drug Resistance Mutations

(2008) G. Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium

(2008) Klas Flärdh et al.   NATURE REVIEWS MICROBIOLOGY