Endothelial dysfunction in (pre)diabetes: Characteristics, causative mechanisms and pathogenic role in type 2 diabetes

The Impact of Exercise Training Compared to Caloric Restriction on Hepatic and Peripheral Insulin Resistance in Obesity

(2014) Robert H. Coker et al.   ENDOCRINE REVIEWS

Endothelial insulin receptor expression in human atherosclerotic plaques: Linking micro- and macrovascular disease in diabetes?

(2012) K.L. Rensing et al.   ATHEROSCLEROSIS

Blockade of the Nuclear Factor-κB Pathway in the Endothelium Prevents Insulin Resistance and Prolongs Life Spans

(2012) Yutaka Hasegawa et al.   CIRCULATION

Overexpression of Endothelial Nitric Oxide Synthase Prevents Diet-Induced Obesity and Regulates Adipocyte Phenotype

(2012) Brian E. Sansbury et al.   CIRCULATION RESEARCH

The evolutionary benefit of insulin resistance

(2012) Maarten R. Soeters et al.   CLINICAL NUTRITION

Perivascular Adipose Tissue Control of Insulin-Induced Vasoreactivity in Muscle Is Impaired in db/db Mice

(2012) R. I. Meijer et al.   DIABETES

Enhanced Cerebral but Not Peripheral Angiogenesis in the Goto-Kakizaki Model of Type 2 Diabetes Involves VEGF and Peroxynitrite Signaling

(2012) R. Prakash et al.   DIABETES

Protein Kinase C  Phosphorylates Occludin Regulating Tight Junction Trafficking in Vascular Endothelial Growth Factor-Induced Permeability In Vivo

(2012) T. Murakami et al.   DIABETES

Insulin-Induced Microvascular Recruitment in Skin and Muscle are Related and Both are Associated with Whole-Body Glucose Uptake

(2012) RICK I. MEIJER et al.   MICROCIRCULATION

Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

(2012) Carolina E. Hagberg et al.   NATURE

Coronary microvascular dysfunction in a porcine model of early atherosclerosis and diabetes

(2011) Mieke van den Heuvel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Macrophage Activation Is Responsible for Loss of Anticontractile Function in Inflamed Perivascular Fat

(2011) Sarah B. Withers et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impaired Insulin Signaling in Endothelial Cells Reduces Insulin-Induced Glucose Uptake by Skeletal Muscle

(2011) Tetsuya Kubota et al.   Cell Metabolism

Adiponectin Is Required for PPARγ-Mediated Improvement of Endothelial Function in Diabetic Mice

(2011) Wing Tak Wong et al.   Cell Metabolism

Endothelin-1 Reduces Glucose Uptake in Human Skeletal Muscle In Vivo and In Vitro

(2011) A. Shemyakin et al.   DIABETES

APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice

(2011) Yi Wang et al.   DIABETES

Thrombospondin-1: An Islet Endothelial Cell Signal of Importance for  -Cell Function

(2011) J. Olerud et al.   DIABETES

The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium

(2011) A. Abbas et al.   DIABETES

Diet-Induced Muscle Insulin Resistance Is Associated With Extracellular Matrix Remodeling and Interaction With Integrin  2 1 in Mice

(2011) L. Kang et al.   DIABETES

Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto–Kakizaki (GK) rat

(2011) M-H. Giroix et al.   DIABETOLOGIA

Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology

(2011) A. K. Berner et al.   DIABETOLOGIA

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

(2011) Goodarz Danaei et al.   LANCET

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

(2011) Tuomas O Kilpeläinen et al.   NATURE GENETICS

Intensive Diabetes Therapy and Glomerular Filtration Rate in Type 1 Diabetes

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Adipose Inflammation Initiates Recruitment of Leukocytes to Mouse Femoral Artery: Role of Adipo-Vascular Axis in Chronic Inflammation

(2011) Sumihiko Hagita et al.   PLoS One

Effect of Early Particulate Air Pollution Exposure on Obesity in Mice

(2010) Xiaohua Xu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Activation of AMP-Activated Protein Kinase by 5-Aminoimidazole-4-Carboxamide-1-β- d -Ribofuranoside in the Muscle Microcirculation Increases Nitric Oxide Synthesis and Microvascular Perfusion

(2010) Eloise A. Bradley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endovascular Injury Induces Rapid Phenotypic Changes in Perivascular Adipose Tissue

(2010) Minoru Takaoka et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Reduction of AMP-Activated Protein Kinase α2 Increases Endoplasmic Reticulum Stress and Atherosclerosis In Vivo

(2010) Yunzhou Dong et al.   CIRCULATION

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

The Portal Theory Supported by Venous Drainage-Selective Fat Transplantation

(2010) J. M. Rytka et al.   DIABETES

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

(2010) O. Brouwers et al.   DIABETOLOGIA

Glucose Intolerance and Impaired Insulin Secretion in Pancreas-Specific Signal Transducer and Activator of Transcription-3 Knockout Mice Are Associated with Microvascular Alterations in the Pancreas

(2010) Elena Kostromina et al.   ENDOCRINOLOGY

Overexpression of Glyoxalase-I Reduces Hyperglycemia-induced Levels of Advanced Glycation End Products and Oxidative Stress in Diabetic Rats

(2010) Olaf Brouwers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vascular endothelial growth factor B controls endothelial fatty acid uptake

(2010) Carolina E. Hagberg et al.   NATURE

Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice

(2010) Mattias Carlström et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intra-arterial AICA-riboside administration induces NO-dependent vasodilation in vivo in human skeletal muscle

(2009) Marlies Bosselaar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Flow Activation of AMP-Activated Protein Kinase in Vascular Endothelium Leads to Krüppel-Like Factor 2 Expression

(2009) Angela Young et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Obesity Promotes Inflammation in Periaortic Adipose Tissue and Angiotensin II-Induced Abdominal Aortic Aneurysm Formation

(2009) Sara B. Police et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Local Inflammation and Hypoxia Abolish the Protective Anticontractile Properties of Perivascular Fat in Obese Patients

(2009) Adam S. Greenstein et al.   CIRCULATION

Proinflammatory Phenotype of Perivascular Adipocytes

(2009) Tapan K. Chatterjee et al.   CIRCULATION RESEARCH

AMP-Activated Protein Kinase Functionally Phosphorylates Endothelial Nitric Oxide Synthase Ser633

(2009) Zhen Chen et al.   CIRCULATION RESEARCH

Diet-Induced Obesity Prevents Interstitial Dispersion of Insulin in Skeletal Muscle

(2009) C. M. Kolka et al.   DIABETES

From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

(2009) R. A. DeFronzo   DIABETES

The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action

(2009) E. J. Barrett et al.   DIABETOLOGIA

Endothelial Nitric Oxide Synthase Uncoupling and Perivascular Adipose Oxidative Stress and Inflammation Contribute to Vascular Dysfunction in a Rodent Model of Metabolic Syndrome

(2009) Chiara Marchesi et al.   HYPERTENSION

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

(2009) Johan Rung et al.   NATURE GENETICS

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

(2009) Jian Liu et al.   NATURE MEDICINE

A Randomized Trial of Therapies for Type 2 Diabetes and Coronary Artery Disease

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue

(2008) Jun Yin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Vascular Inflammation, Insulin Resistance, and Reduced Nitric Oxide Production Precede the Onset of Peripheral Insulin Resistance

(2008) Francis Kim et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

AMPK and PPARδ Agonists Are Exercise Mimetics

(2008) Vihang A. Narkar et al.   CELL

Adventitial Mast Cells Contribute to Pathogenesis in the Progression of Abdominal Aortic Aneurysm

(2008) Toshihiro Tsuruda et al.   CIRCULATION RESEARCH

Effect of Endothelium-Specific Insulin Resistance on Endothelial Function In Vivo

(2008) E. R. Duncan et al.   DIABETES

Direct Administration of Insulin Into Skeletal Muscle Reveals That the Transport of Insulin Across the Capillary Endothelium Limits the Time Course of Insulin to Activate Glucose Disposal

(2008) J. D. Chiu et al.   DIABETES

Preglomerular and postglomerular basal diameter changes and reactivity to angiotensin II in obese rats

(2008) M. H. Roos et al.   DIABETES OBESITY & METABOLISM

Protein Kinase C θ (PKCθ)-dependent Phosphorylation of PDK1 at Ser504and Ser532Contributes to Palmitate-induced Insulin Resistance

(2008) Changhua Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreasing Intracellular Superoxide Corrects Defective Ischemia-induced New Vessel Formation in Diabetic Mice

(2008) Daniel J. Ceradini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Associations of Serum Adiponectin with Skeletal Muscle Morphology and Insulin Sensitivity

(2008) Erik Ingelsson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM