Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection

HIV Infection Deregulates Tim-3 Expression on Innate Cells

(2013) Constance A.M. Finney et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Galectin-9 Functionally Impairs Natural Killer Cells in Humans and Mice

(2013) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

TIM-3 Does Not Act as a Receptor for Galectin-9

(2013) Judith Leitner et al.   PLoS Pathogens

Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity

(2012) L. C. Ndhlovu et al.   BLOOD

Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9

(2012) M. K. Gleason et al.   BLOOD

Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection

(2012) S. Elahi et al.   BLOOD

Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma

(2012) Hang Li et al.   HEPATOLOGY

Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

(2012) Shigeki Chiba et al.   NATURE IMMUNOLOGY

Tim-3 Negatively Regulates Cytotoxicity in Exhausted CD8+ T Cells in HIV Infection

(2012) Ali Sakhdari et al.   PLoS One

HIV-1 adaptation to NK-cell-mediated immune pressure

(2011) Galit Alter et al.   NATURE

Cross-Sectional Detection of Acute HIV Infection: Timing of Transmission, Inflammation and Antiretroviral Therapy

(2011) Cynthia Gay et al.   PLoS One

Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry

(2011) S. Bi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HCV-specific T cells in HCV/HIV co-infection show elevated frequencies of dual Tim-3/PD-1 expression that correlate with liver disease progression

(2010) Bahareh Vali et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Innate immunity defines the capacity of antiviral T cells to limit persistent infection

(2010) Daniel M. Andrews et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer cell suppression in chronic hepatitis B

(2010) Ying Ju et al.   JOURNAL OF HEPATOLOGY

HIV Protective KIR3DL1 and HLA-B Genotypes Influence NK Cell Function Following Stimulation with HLA-Devoid Cells

(2010) Salix Boulet et al.   JOURNAL OF IMMUNOLOGY

T Cell/Transmembrane, Ig, and Mucin-3 Allelic Variants Differentially Recognize Phosphatidylserine and Mediate Phagocytosis of Apoptotic Cells

(2010) Rosemarie H. DeKruyff et al.   JOURNAL OF IMMUNOLOGY

A combined genotype of KIR3DL1 high expressing alleles and HLA-B*57 is associated with a reduced risk of HIV infection

(2009) Salix Boulet et al.   AIDS

Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals

(2009) Salix Boulet et al.   AIDS

IL-21 augments natural killer effector functions in chronically HIV-infected individuals

(2009) Natasa Strbo et al.   AIDS

Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

(2009) M. Nakayama et al.   BLOOD

HLA Class I Subtype-Dependent Expansion of KIR3DS1+ and KIR3DL1+ NK Cells during Acute Human Immunodeficiency Virus Type 1 Infection

(2009) G. Alter et al.   JOURNAL OF VIROLOGY

Role of Natural Killer Cells in a Cohort of Elite Suppressors: Low Frequency of the Protective KIR3DS1 Allele and Limited Inhibition of Human Immunodeficiency Virus Type 1 Replication In Vitro

(2009) K. A. O'Connell et al.   JOURNAL OF VIROLOGY

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

(2009) A. R. Stacey et al.   JOURNAL OF VIROLOGY

Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells

(2009) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

Structural Features of Galectin-9 and Galectin-1 That Determine Distinct T Cell Death Pathways

(2008) Shuguang Bi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE