Article
Chemistry, Analytical
Nattapong Chantipmanee, Jasmine S. Furter, Peter C. Hauser
Summary: The instrument is based on a miniature plasma source, which enables rapid identification of different drugs and components in coffee, with the advantages of low cost and easy replication.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Moritz Hitzemann, Christoph Schaefer, Ansgar T. Kirk, Alexander Nitschke, Martin Lippmann, Stefan Zimmermann
Summary: In this paper, a new and easy to assemble dielectric barrier discharge plasma ionization source is presented, which is based on printed circuit boards with two parallel isolated electrodes for generating plasma inside an inert fused silica capillary. The plasma source is coupled to an ion mobility spectrometer for demonstration. Different ionization pathways can be achieved by whether the analytes pass through the plasma or bypass it before entering the reaction region of the ion mobility spectrometer. The plasma source has been designed using electric field simulations and can reach detection limits in the mid pptv range.
ANALYTICA CHIMICA ACTA
(2023)
Article
Biochemical Research Methods
Christian Thoben, Nora T. Hartner, Moritz Hitzemann, Christian-Robert Raddatz, Manuel Eckermann, Detlev Belder, Stefan Zimmermann
Summary: The influence of solvents and buffer additives on the detected ion mobility peaks using ESI is investigated in this study. It is found that the ionization process during electrospray can be influenced by the choice of additives. By carefully selecting the solvent additives, the formation of different ion mobility peaks can be observed.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2023)
Article
Chemistry, Analytical
Jing He, Wenxin Wang, Hong Zhang, Yun Ju, Kai Yu, Xiangnan Zhang, Jie Jiang
Summary: A new method for rapid, simple and sensitive analysis of low-polar acenaphthene was proposed using N-DBDI. The method improved sensitivity, with results showing high accuracy and precision in analyzing environmental samples.
Article
Chemistry, Analytical
Qian He, Ningxin Zhang, Yifan Qiao, Chenchen Li, Jing Zhang
Summary: Pneumatic nebulization technology allows for the spontaneous conversion of mercury ions into volatile elemental mercury through aqueous microdroplets without the need for added redox agents, electricity, or radiation. This innovative and low-energy method has the potential to contribute to green chemistry and the global atmospheric mercury cycle.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Chemistry, Analytical
Eric J. Davis, David Walker, Molly Gibney, Brian H. Clowers
Summary: The research investigated the transition between ESI and CDI modes with respect to applied bias, revealing that CDI reaches stable state faster in positive mode compared to ESI, while stability in negative mode varies greatly in both modes. When examining the resultant ions, it was found that the impact of increased bias on an ESI needle was species-dependent, with labile species showing significant fragmentation at higher biases.
Article
Chemistry, Multidisciplinary
Sen Li, Jiazhen Sun, Rui Sun, Jie Pan, Lin Wang, Chen Chen, Qiang Chen, Zhongwei Liu
Summary: This paper investigates the radio frequency dielectric barrier discharge using argon at atmospheric pressure. It observed alpha mode and gamma mode discharges, and analyzed the luminescence intensity at different locations in the discharge gap. It was found that in gamma mode, the negative glow appears with a delay of 13 +/- 1 ns compared to the electron avalanche in alpha mode.
APPLIED SCIENCES-BASEL
(2021)
Article
Biochemical Research Methods
Qinlei Liu, Renato Zenobi
Summary: This study introduced a DBDI-MS-based analytical method for detecting and quantifying fragrance allergens. The method showed high sensitivity and fast analysis time, making it suitable for quality control of consumer products in the cosmetics market.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2021)
Article
Physics, Applied
Antoine Belinger, Simon Dap, Nicolas Naude
Summary: This study focuses on a diffuse Dielectric Barrier Discharge (DBD) in atmospheric pressure air and investigates the influence of capacitance on the discharge regime. By modifying the dielectric capacitance and using electrical measurements, the effective surface and current density of the discharge were obtained. The results highlight the significance of controlling capacitance to achieve diffuse discharge at high frequency, which has potential applications in atmospheric pressure coating.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Qinlei Liu, Wenjie Ge, Tongtong Wang, Jiayi Lan, Sandra Martinez-Jarquin, Christian Wolfrum, Markus Stoffel, Renato Zenobi
Summary: A rapid, label-free single-cell analysis method based on mass spectrometry was proposed, allowing for efficient analysis of metabolites and successful discrimination of multiple cell types. Evidence of abnormal lipid metabolism in pancreatic cancer cells was found, indicating a potential therapeutic target.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Analytical
Juan F. Ayala-Cabrera, Jasmin Turkowski, Florian Uteschil, Oliver J. Schmitz
Summary: A tube plasma ionization (TPI) open-air source for gas chromatography-mass spectrometry (GC-MS) was developed, and its ionization capabilities were tested using various analytes. Different discharge gases and auxiliary gases were investigated, along with the effects of adding water. Compared to other atmospheric pressure ionization sources, TPI showed a wider range of compound ionization and better detection capability.
ANALYTICAL CHEMISTRY
(2022)
Article
Physics, Fluids & Plasmas
Chen Zhou, Chengxun Yuan, Anatoly Kudryavtsev, T. Yasar Katircioglu, Ismail Rafatov, Jingfeng Yao
Summary: This study focuses on the numerical investigation of dielectric barrier discharge in atmospheric pressure CO2 in a coaxial reactor. Using a numerical model based on the drift-diffusion theory and considering gas heating in a self-consistent manner, the study examines the influence of gas heating on discharge properties and CO2 decomposition across a wide range of applied voltage amplitudes and frequencies. The calculations indicate that neglecting gas heating by assuming a constant (room) gas temperature leads to a significant overestimation of CO2 conversion.
PLASMA SOURCES SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Physical
Jumal Ibrahim, Sameer A. Al-Babtaineh, Samuel Cousens, Andrew Michelmore, Cormac Corr, Jason Whittle
Summary: This article investigates the discharge characteristics of an atmospheric pressure surface dielectric barrier discharge (SDBD) generated in helium and its ability to produce amine functionalised polymer coatings for cell therapy applications. The experimental results show that the plasma device is capable of generating glow-like discharge structures that are stable over the electrode area, and high electric fields around the mesh electrode. The surface characterisation of the coating revealed rich amine functionality, potentially suitable for cell adhesion and growth.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Analytical
Jiahui Yang, Yao Lin, Liangbo He, Yubin Su, Xiandeng Hou, Yurong Deng, Chengbin Zheng
Summary: This study developed a portable and compact system device for field speciation analyses of mercury and inorganic selenium using 3D printing technology. The device showed improved accuracy and practicality in analysis, highlighting the potential of 3D printing for creating simple and efficient atomic spectrometers for field elemental speciation analysis.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Sen Li, Jiazhen Sun, Rui Sun, Jie Pan, Lin Wang, Chen Chen, Qiang Chen, Zhongwei Liu
Summary: In this study, the characteristics of radio frequency dielectric barrier discharge (RF-DBD) using argon doped with nitrogen at atmospheric pressure were investigated. It was found that the discharge changed from glow discharge to filamentous discharge as the voltage increased, with the morphology of the filaments depending on the nitrogen doping ratio.
Article
Chemistry, Analytical
David Moreno-Gonzalez, Delia Castilla-Fernandez, Pascal Vogel, Guanghui Niu, Sebastian Brandt, Carolin Drees, Juan F. Garcia-Reyes, Antonio Molina-Diaz, Joachim Franzke
Summary: This study evaluated the potential of a new plasma-based soft ionization source named CA-F mu TP for the determination of BTEX group in olive oil, showing advantages over EI with easier identification of BTEX mass spectrum. The sensitivity of CA-FmTP was comparable to EI, demonstrating potential usefulness for BTEX analysis in fatty complex matrixes like olive oil.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Applied
Delia Castilla-Fernandez, David Moreno-Gonzalez, Juan F. Garcia-Reyes, Evaristo Ballesteros, Antonio Molina-Diaz
Summary: Datura species are known for their high concentration of tropane alkaloids, which can lead to poisoning when accidentally mixed with edible crops. Testing on frozen spinach and spinach-based infant food products found that some samples had levels close to the maximum limits set by the European Union. This highlights the global concern over the presence of these compounds in various commodities.
Article
Chemistry, Applied
Delia Castilla-Fernandez, David Moreno-Gonzalez, Bienvenida Gilbert-Lopez, Juan F. Garcia-Reyes, Antonio Molina-Diaz
Summary: Despite efforts to address pesticide residues in citrus-flavored soft drinks over more than ten years, a new study shows that the issue persists. Globally, 98% of samples were found to contain at least one pesticide, with 85% having more than 4 pesticides. Europe had the highest total amount of pesticides, likely due to higher juice concentrate content in samples.
Article
Chemistry, Analytical
Marcos Bouza, Julio Garcia-Martinez, Bienvenida Gilbert-Lopez, David Moreno-Gonzalez, Priscilla Rocio-Bautista, David Parras-Guijarro, Alberto Sanchez-Vizcaino, Sebastian Brandt, Juan F. Garcia-Reyes, Antonio Molina-Diaz, Joachim Franzke
Summary: Dielectric barrier discharge ionization is a versatile technique for ionizing a wide range of molecules, including neutral lipids. This study evaluated the use of liquid chromatography coupled with dielectric barrier discharge ionization mass spectrometry for neutral lipid analysis. The results showed that this technique can provide improved sensitivity and comparable or better quantitation limits compared to atmospheric pressure chemical ionization. The analysis of archaeological samples revealed the potential vegetal origin of the stored material based on the presence of unsaturation and sterols.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Chemistry, Analytical
Lucia Bartella, Marcos Bouza, Priscilla Rocio-Bautista, Leonardo Di Donna, Juan F. Garcia-Reyes, Antonio Molina-Diaz
Summary: Ambient mass spectrometry is an alternative to classical mass spectrometry that allows fast, in-situ, and high-throughput analysis of samples with minimal sample pretreatment. This study explores the capability of different ambient ionization sources to analyze raw wine for quality control purposes. The spectra obtained from these sources showed the ability to classify and differentiate wine samples based on various compounds, including organic acids, phenolic acids, derivatives, and low-molecular-mass flavonoids. The plasma-based methods offer the advantage of solventless analysis, while the paper spray (PS) approach provides a richer MS profile.
MICROCHEMICAL JOURNAL
(2022)
Article
Food Science & Technology
Delia Castilla-Fernandez, Priscilla Rocio-Bautista, David Moreno-Gonzalez, Juan F. Garcia-Reyes, Antonio Molina-Diaz
Summary: This study examined the extraction of mycotoxins from walnuts using solid-liquid extraction (SLE) and explored various clean-up methods. The main limitation in analyzing mycotoxins in fatty matrices was the strong matrix effect encountered. However, dilution and injection proved to be effective in reducing the matrix effect, and a viable dilute-and-shoot method was proposed.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Marcos Bouza, Julio Garcia-Martinez, Bienvenida Gilbert-Lopez, Sebastian Brandt, Juan F. Garcia-Reyes, Antonio Molina-Diaz, Joachim Franzke
Summary: Dielectric barrier discharge ionization (DBDI) is a versatile tool for small-molecule mass spectrometry applications, covering a wide range of molecules from polar to low polar. However, the complex plasma gas-phase interactions in DBDI have not been well studied. In this study, the ionization mechanisms of a two-ring DBDI ion source were evaluated using different discharge gases for vaporized liquid samples. The results showed that APCI and DBDI exhibited different ionization trends during PAH analysis, with APCI mainly producing [M + H]+ ions and DBDI showing the prevalence of charge exchange reactions. The addition of dopants in the gas phase shifted the ionization mechanisms towards charge exchange reactions and facilitated the formation of [M]??+ ion species.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Applied
Atalanti Christou, Ana B. Martinez-Piernas, Ioannis J. Stavrou, Juan F. Garcia-Reyes, Constantina P. Kapnissi-Christodoulou
Summary: The effects of ripening stage, processing method, and geographical origin on the chemical composition and properties of Carob were investigated in this study using HPLC-ESI-HRMS and chemometric analysis. The study found that Carob seeds had higher levels of polyphenols, and unripe pods were richer in polyphenols. Carob processing, particularly thermal treatment, also led to noticeable changes in its chemical composition. The geographical origin also had an impact on the phenolic composition of Carob.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Review
Chemistry, Analytical
Priscilla Rocio-Bautista, David Moreno-Gonzalez, Ana B. Martinez-Piernas, Juan F. Garcia-Reyes, Antonio Molina-Diaz
Summary: This review discusses the application of liquid chromatography-mass spectrometry (LC-MS) technique in the determination of glyphosate (Gly) and related compounds. The sample preparation methods and novel liquid chromatography/mass spectrometry approaches are introduced, and the analytical challenges, strengths, and drawbacks are critically discussed.
TRENDS IN ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Marcos Bouza, Norman Ahlmann, Juan F. Garcia-Reyes, Joachim Franzke
Summary: The present study investigated the potential of SALD-FμTP-MS as a rapid analytical technique for direct analysis of surface-deposited samples. Paper was used as the substrate and an infrared hand-held laser was employed for sample desorption. The optimization process involved the use of viscous solvents to enhance desorption and ionization efficiencies. Ethylene glycol (EG) was identified as a suitable solvent, improving sensitivity and substrate stability. The applicability of SALD-FμTP-MS was demonstrated by successfully analyzing food, water, and biological samples, particularly for thermolabile and polarity diverse compounds.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Andres J. Rascon, Priscilla Rocio-Bautista, David Moreno-Gonzalez, Juan F. Garcia-Reyes, Evaristo Ballesteros
Summary: The metal-organic framework CIM-80(Al) was proposed as a sorbent coating for solid-phase microextraction fibers. The CIM-80(Al)-based microextraction fibers with a thickness of 3.5 μm were used to isolate and determine 14 phthalate esters in bottled water with promising results. The extraction efficiency was comparable to commercial coatings in a total of 16 bottled water samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Education, Scientific Disciplines
Marcos Bouza, Bienvenida Gilbert-Lopez, Juan Francisco Garcia-Reyes, Pilar Gema Rodriguez Ortega
Summary: High-resolution mass spectrometry (HRMS) is becoming more affordable and user-friendly, with a wide range of applications. The experiment demonstrates the powerful and useful nature of HRMS in addressing research projects and chemistry problems, providing opportunities for discussions related to measurement precision and accuracy in an analytical chemistry context.
CHEMISTRY TEACHER INTERNATIONAL
(2022)
