High-throughput screening for glutathione conjugates using stable-isotope labeling and negative electrospray ionization precursor-ion mass spectrometry

In Vitro Screening of 50 Highly Prescribed Drugs for Thiol Adduct FormationComparison of Potential for Drug-Induced Toxicity and Extent of Adduct Formation

(2009) Jinping Gan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Unbiased High-Throughput Screening of Reactive Metabolites on the Linear Ion Trap Mass Spectrometer Using Polarity Switch and Mass Tag Triggered Data-Dependent Acquisition

(2008) Zhengyin Yan et al.   ANALYTICAL CHEMISTRY

Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug

(2008) J. N. Bauman et al.   DRUG METABOLISM AND DISPOSITION

Understanding the role of reactive metabolites in drug-induced hepatotoxicity: state of the science

(2008) Daniel J Antoine et al.   Expert Opinion on Drug Metabolism & Toxicology

An algorithm for thorough background subtraction from high-resolution LC/MS data: application for detection of glutathione-trapped reactive metabolites

(2008) Haiying Zhang et al.   JOURNAL OF MASS SPECTROMETRY

Toxicophores, reactive metabolites and drug safety: when is it a cause for concern?

(2008) Amit S Kalgutkar et al.   Expert Review of Clinical Pharmacology