Single-molecule views on homologous recombination

Single-Stranded DNA Curtains for Real-Time Single-Molecule Visualization of Protein–Nucleic Acid Interactions

(2012) Bryan Gibb et al.   ANALYTICAL CHEMISTRY

Recent Advances in Magnetic Tweezers

(2012) Iwijn De Vlaminck et al.   Annual Review of Biophysics

Single-Molecule Views of Protein Movement on Single-Stranded DNA

(2012) Taekjip Ha et al.   Annual Review of Biophysics

Mechanism of Homology Recognition in DNA Recombination from Dual-Molecule Experiments

(2012) Iwijn De Vlaminck et al.   MOLECULAR CELL

Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA

(2012) Jason C. Bell et al.   NATURE

Single-molecule imaging of DNA pairing by RecA reveals a three-dimensional homology search

(2012) Anthony L. Forget et al.   NATURE

Defective homologous recombination in human cancers

(2011) A. Cerbinskaite et al.   CANCER TREATMENT REVIEWS

Highly Parallel Magnetic Tweezers by Targeted DNA Tethering

(2011) Iwijn De Vlaminck et al.   NANO LETTERS

Ultrahigh-resolution optical trap with single-fluorophore sensitivity

(2011) Matthew J Comstock et al.   NATURE METHODS

Quantifying how DNA stretches, melts and changes twist under tension

(2011) Peter Gross et al.   Nature Physics

Unraveling the mechanism of BRCA2 in homologous recombination

(2011) William K Holloman   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Changes in the tension in dsDNA alter the conformation of RecA bound to dsDNA–RecA filaments

(2011) Alyson J. Conover et al.   NUCLEIC ACIDS RESEARCH

Combining optical trapping, fluorescence microscopy and micro-fluidics for single molecule studies of DNA–protein interactions

(2011) Andrea Candelli et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Real-Time Observation of Strand Exchange Reaction with High Spatiotemporal Resolution

(2011) Kaushik Ragunathan et al.   STRUCTURE

Freely orbiting magnetic tweezers to directly monitor changes in the twist of nucleic acids

(2011) Jan Lipfert et al.   Nature Communications

Regulation of Homologous Recombination in Eukaryotes

(2010) Wolf-Dietrich Heyer et al.   Annual Review of Genetics

Defining the Limits of Single-Molecule FRET Resolution in TIRF Microscopy

(2010) Seamus J. Holden et al.   BIOPHYSICAL JOURNAL

Purified human BRCA2 stimulates RAD51-mediated recombination

(2010) Ryan B. Jensen et al.   NATURE

Magnetic torque tweezers: measuring torsional stiffness in DNA and RecA-DNA filaments

(2010) Jan Lipfert et al.   NATURE METHODS

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA

(2010) Jie Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Caught in the act: the lifetime of synaptic intermediates during the search for homology on DNA

(2010) Adam Mani et al.   NUCLEIC ACIDS RESEARCH

Separation of time scales in one-dimensional directed nucleation-growth processes

(2010) Paolo Pierobon et al.   PHYSICAL REVIEW E

Nanofabricated Racks of Aligned and Anchored DNA Substrates for Single-Molecule Imaging

(2009) Jason Gorman et al.   LANGMUIR

Dynamics of RecA filaments on single-stranded DNA

(2009) Marijn T. J. van Loenhout et al.   NUCLEIC ACIDS RESEARCH

A high-resolution magnetic tweezer for single-molecule measurements

(2009) Kipom Kim et al.   NUCLEIC ACIDS RESEARCH

Direct observation of twisting steps during Rad51 polymerization on DNA

(2009) H. Arata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of human Rad51 protein filament from molecular modeling and site-specific linear dichroism spectroscopy

(2009) A. Reymer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

(2009) J. Hilario et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging

(2009) J. van Mameren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural transitions within human Rad51 nucleoprotein filaments

(2009) R. B. Robertson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational transitions in DNA polymerase I revealed by single-molecule FRET

(2009) Y. Santoso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Recent Advances in Optical Tweezers

(2008) Jeffrey R. Moffitt et al.   Annual Review of Biochemistry

Monte Carlo Simulations of Protein Assembly, Disassembly, and Linear Motion on DNA

(2008) Thijn van der Heijden et al.   BIOPHYSICAL JOURNAL

Inhibition of filament formation of human Rad51 protein by a small peptide derived from the BRC-motif of the BRCA2 protein

(2008) Julian Nomme et al.   GENES TO CELLS

Homologous Recombination in Real Time: DNA Strand Exchange by RecA

(2008) Thijn van der Heijden et al.   MOLECULAR CELL

Counting RAD51 proteins disassembling from nucleoprotein filaments under tension

(2008) Joost van Mameren et al.   NATURE

Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures

(2008) Zhucheng Chen et al.   NATURE

Laminar flow cells for single-molecule studies of DNA-protein interactions

(2008) Laurence R Brewer et al.   NATURE METHODS

A practical guide to single-molecule FRET

(2008) Rahul Roy et al.   NATURE METHODS

Visualizing one-dimensional diffusion of proteins along DNA

(2008) Jason Gorman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Finding a match: how do homologous sequences get together for recombination?

(2007) Adi Barzel et al.   NATURE REVIEWS GENETICS