Single-Molecule Views of Protein Movement on Single-Stranded DNA

SSB Functions as a Sliding Platform that Migrates on DNA via Reptation

(2011) Ruobo Zhou et al.   CELL

Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding

(2011) Masayoshi Honda et al.   EMBO JOURNAL

Rotations of the 2B Sub-domain of E. coli UvrD Helicase/Translocase Coupled to Nucleotide and DNA Binding

(2011) Haifeng Jia et al.   JOURNAL OF MOLECULAR BIOLOGY

Single-molecule analysis reveals three phases of DNA degradation by an exonuclease

(2011) Gwangrog Lee et al.   Nature Chemical Biology

High-throughput single-molecule optofluidic analysis

(2011) Soohong Kim et al.   NATURE METHODS

Changes in the tension in dsDNA alter the conformation of RecA bound to dsDNA–RecA filaments

(2011) Alyson J. Conover et al.   NUCLEIC ACIDS RESEARCH

Steric exclusion and wrapping of the excluded DNA strand occurs along discrete external binding paths during MCM helicase unwinding

(2011) Brian W. Graham et al.   NUCLEIC ACIDS RESEARCH

The RecA/RAD51 protein drives migration of Holliday junctions via polymerization on DNA

(2011) M. J. Rossi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrokinetic trapping at the one nanometer limit

(2011) A. P. Fields et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein induced fluorescence enhancement as a single molecule assay with short distance sensitivity

(2011) H. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-Time Observation of Strand Exchange Reaction with High Spatiotemporal Resolution

(2011) Kaushik Ragunathan et al.   STRUCTURE

Single-Molecule Four-Color FRET

(2010) Jinwoo Lee  et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single-Molecule TPM Studies on the Conversion of Human Telomeric DNA

(2010) Jen-Fei Chu et al.   BIOPHYSICAL JOURNAL

PcrA Helicase Dismantles RecA Filaments by Reeling in DNA in Uniform Steps

(2010) Jeehae Park et al.   CELL

Stepwise translocation of nucleic acid motors

(2010) Sua Myong et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

5′-Single-stranded/duplex DNA junctions are loading sites for E. coli UvrD translocase

(2010) Eric J Tomko et al.   EMBO JOURNAL

The Nature of the Force-Induced Conformation Transition of dsDNA Studied by Using Single Molecule Force Spectroscopy

(2010) Ningning Liu et al.   LANGMUIR

Single-molecule imaging reveals mechanisms of protein disruption by a DNA translocase

(2010) Ilya J. Finkelstein et al.   NATURE

Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA

(2010) Máté Gyimesi et al.   NUCLEIC ACIDS RESEARCH

Active and passive mechanisms of helicases

(2010) Maria Manosas et al.   NUCLEIC ACIDS RESEARCH

Visualizing helicases unwinding DNA at the single molecule level

(2010) Natali Fili et al.   NUCLEIC ACIDS RESEARCH

Torsional regulation of hRPA-induced unwinding of double-stranded DNA

(2010) Iwijn De Vlaminck et al.   NUCLEIC ACIDS RESEARCH

Human Rad52 binds and wraps single-stranded DNA and mediates annealing via two hRad52–ssDNA complexes

(2010) Jill M. Grimme et al.   NUCLEIC ACIDS RESEARCH

Direct Observation of Multiple Pathways of Single-Stranded DNA Stretching

(2010) Wuen-shiu Chen et al.   PHYSICAL REVIEW LETTERS

Helix-Coil Kinetics of Individual Polyadenylic Acid Molecules in a Protein Channel

(2010) Jianxun Lin et al.   PHYSICAL REVIEW LETTERS

Single-Molecule Analysis Reveals the Kinetics and Physiological Relevance of MutL-ssDNA Binding

(2010) Jonghyun Park et al.   PLoS One

Insight into helicase mechanism and function revealed through single-molecule approaches

(2010) Jaya G. Yodh et al.   QUARTERLY REVIEWS OF BIOPHYSICS

RNA helicases at work: binding and rearranging

(2010) Eckhard Jankowsky   TRENDS IN BIOCHEMICAL SCIENCES

BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation

(2009) Jaya G Yodh et al.   EMBO JOURNAL

Single-Stranded DNA-Binding Protein Complex from Helicobacter pylori Suggests an ssDNA-Binding Surface

(2009) Kun-Wei Chan et al.   JOURNAL OF MOLECULAR BIOLOGY

ILPR G-Quadruplexes Formed in Seconds Demonstrate High Mechanical Stabilities

(2009) Zhongbo Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Molecule Analysis Reveals Differential Effect of ssDNA-Binding Proteins on DNA Translocation by XPD Helicase

(2009) Masayoshi Honda et al.   MOLECULAR CELL

Srs2 Disassembles Rad51 Filaments by a Protein-Protein Interaction Triggering ATP Turnover and Dissociation of Rad51 from DNA

(2009) Edwin Antony et al.   MOLECULAR CELL

SSB protein diffusion on single-stranded DNA stimulates RecA filament formation

(2009) Rahul Roy et al.   NATURE

Dynamics of RecA filaments on single-stranded DNA

(2009) Marijn T. J. van Loenhout et al.   NUCLEIC ACIDS RESEARCH

Nonlinear Low-Force Elasticity of Single-Stranded DNA Molecules

(2009) O. A. Saleh et al.   PHYSICAL REVIEW LETTERS

Direct observation of twisting steps during Rad51 polymerization on DNA

(2009) H. Arata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

(2009) J. Hilario et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural transitions within human Rad51 nucleoprotein filaments

(2009) R. B. Robertson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytosolic Viral Sensor RIG-I Is a 5'-Triphosphate-Dependent Translocase on Double-Stranded RNA

(2009) S. Myong et al.   SCIENCE

Advances in Single-Molecule Fluorescence Methods for Molecular Biology

(2008) Chirlmin Joo et al.   Annual Review of Biochemistry

SSB as an Organizer/Mobilizer of Genome Maintenance Complexes

(2008) Robert D. Shereda et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Impediment of E. coli UvrD by DNA-destabilizing force reveals a strained-inchworm mechanism of DNA unwinding

(2008) Bo Sun et al.   EMBO JOURNAL

Homologous Recombination in Real Time: DNA Strand Exchange by RecA

(2008) Thijn van der Heijden et al.   MOLECULAR CELL

Counting RAD51 proteins disassembling from nucleoprotein filaments under tension

(2008) Joost van Mameren et al.   NATURE

Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures

(2008) Zhucheng Chen et al.   NATURE

Do-it-yourself guide: how to use the modern single-molecule toolkit

(2008) Nils G Walter et al.   NATURE METHODS

Non-hexameric DNA helicases and translocases: mechanisms and regulation

(2008) Timothy M. Lohman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Single-molecule detection of folding and unfolding of the G-quadruplex aptamer in a nanopore nanocavity

(2008) Ji Wook Shim et al.   NUCLEIC ACIDS RESEARCH

Kinetics and thermodynamics of salt-dependent T7 gene 2.5 protein binding to single- and double-stranded DNA

(2008) L. Shokri et al.   NUCLEIC ACIDS RESEARCH

Human Rad52-mediated homology search and annealing occurs by continuous interactions between overlapping nucleoprotein complexes

(2008) E. Rothenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cooperative binding of ATP and RNA induces a closed conformation in a DEAD box RNA helicase

(2008) B. Theissen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Slide into Action: Dynamic Shuttling of HIV Reverse Transcriptase on Nucleic Acid Substrates

(2008) S. Liu et al.   SCIENCE

VirE2: A Unique ssDNA-Compacting Molecular Machine

(2008) Wilfried Grange et al.   PLOS BIOLOGY