Occupancy of dopamine D2 and D3 and serotonin 5-HT1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography

Imaging Dopamine D3 Receptors in the Human Brain with Positron Emission Tomography, [11C]PHNO, and a Selective D3 Receptor Antagonist

(2010) Graham Searle et al.   BIOLOGICAL PSYCHIATRY

Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist-Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile

(2010) B. Kiss et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Imaging dopamine receptors in humans with [11C]-(+)-PHNO: Dissection of D3 signal and anatomy

(2010) Andri C. Tziortzi et al.   NEUROIMAGE

The Effect of Antipsychotics on the High-Affinity State of D2 and D3 Receptors

(2009) Ariel Graff-Guerrero et al.   ARCHIVES OF GENERAL PSYCHIATRY

Dopamine D2/3receptor occupancy of apomorphine in the nonhuman primate brain-A comparative PET study with [11C]raclopride and [11C]MNPA

(2009) Sjoerd J. Finnema et al.   SYNAPSE

Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2and D3dopamine receptors

(2009) Mette Skinbjerg et al.   SYNAPSE

In vivo quantification of regional dopamine-D3 receptor binding potential of (+)-PHNO: Studies in non-human primates and transgenic mice

(2009) Eugenii A. Rabiner et al.   SYNAPSE

The Role of Molecular Imaging in Drug Discovery and Development

(2008) RJ Hargreaves   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Role of Imaging in Proof of Concept for CNS Drug Discovery and Development

(2008) Dean F Wong et al.   NEUROPSYCHOPHARMACOLOGY