Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
出版年份 2015 全文链接
标题
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
作者
关键词
-
出版物
Nature Communications
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-01-29
DOI
10.1038/ncomms6897
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
- (2014) Leslie A. Lange et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks
- (2014) Gina M. Peloso et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A Common Functional Regulatory Variant at a Type 2 Diabetes Locus Upregulates ARAP1 Expression in the Pancreatic Beta Cell
- (2014) Jennifer R. Kulzer et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk
- (2014) Oddgeir L Holmen et al. NATURE GENETICS
- Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
- (2014) Jason Flannick et al. NATURE GENETICS
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
- (2014) Anubha Mahajan et al. NATURE GENETICS
- Searching for missing heritability: Designing rare variant association studies
- (2014) O. Zuk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci
- (2014) Susan K. Service et al. PLoS Genetics
- Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels
- (2013) D. A. Baerenwald et al. DIABETOLOGIA
- dbNSFP v2.0: A Database of Human Non-synonymous SNVs and Their Functional Predictions and Annotations
- (2013) Xiaoming Liu et al. HUMAN MUTATION
- Whole-genome sequence–based analysis of high-density lipoprotein cholesterol
- (2013) Alanna C Morrison et al. NATURE GENETICS
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium
- (2013) Megan L. Grove et al. PLoS One
- Glucagon-like peptide 1 and appetite
- (2013) Megan J. Dailey et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- zCall: a rare variant caller for array-based genotyping
- (2012) Jacqueline I. Goldstein et al. BIOINFORMATICS
- An integrative variant analysis suite for whole exome next-generation sequencing data
- (2012) Danny Challis et al. BMC BIOINFORMATICS
- Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants
- (2012) Wenqing Fu et al. NATURE
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
- (2012) NATURE GENETICS
- Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
- (2012) Robert A Scott et al. NATURE GENETICS
- A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
- (2012) Alisa K Manning et al. NATURE GENETICS
- Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion
- (2012) Jeroen R Huyghe et al. NATURE GENETICS
- ENCODE Data in the UCSC Genome Browser: year 5 update
- (2012) Kate R. Rosenbloom et al. NUCLEIC ACIDS RESEARCH
- Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptor
- (2012) A. Kirkpatrick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
- (2012) J. A. Tennessen et al. SCIENCE
- An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People
- (2012) M. R. Nelson et al. SCIENCE
- Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants
- (2012) A. Keinan et al. SCIENCE
- NARWHAL, a primary analysis pipeline for NGS data
- (2011) R. W. W. Brouwer et al. BIOINFORMATICS
- The variant call format and VCFtools
- (2011) P. Danecek et al. BIOINFORMATICS
- Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk
- (2011) M. G. Rees et al. DIABETOLOGIA
- Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
- (2011) A Astrup et al. INTERNATIONAL JOURNAL OF OBESITY
- Polymorphism and Ligand Dependent Changes in Human Glucagon-Like Peptide-1 Receptor (GLP-1R) Function: Allosteric Rescue of Loss of Function Mutation
- (2011) C. Koole et al. MOLECULAR PHARMACOLOGY
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
- (2011) Heribert Schunkert et al. NATURE GENETICS
- A framework for variation discovery and genotyping using next-generation DNA sequencing data
- (2011) Mark A DePristo et al. NATURE GENETICS
- G protein-coupled receptors: mutations and endocrine diseases
- (2011) Gilbert Vassart et al. Nature Reviews Endocrinology
- Association between birth weight and visceral fat in adults
- (2010) Emanuella De Lucia Rolfe et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Genetics and phenomics of inherited and sporadic non-autoimmune hyperthyroidism
- (2010) Hulya Iliksu Gozu et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Biological, clinical and population relevance of 95 loci for blood lipids
- (2010) Tanya M. Teslovich et al. NATURE
- Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
- (2010) Richa Saxena et al. NATURE GENETICS
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
- (2010) Josée Dupuis et al. NATURE GENETICS
- Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
- (2010) Benjamin F Voight et al. NATURE GENETICS
- Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits
- (2010) Ayellet V. Segrè et al. PLoS Genetics
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium
- (2009) Bruce M. Psaty et al. Circulation-Cardiovascular Genetics
- SNP detection for massively parallel whole-genome resequencing
- (2009) R. Li et al. GENOME RESEARCH
- The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver
- (2009) Nicola L. Beer et al. HUMAN MOLECULAR GENETICS
- CHARMM: The biomolecular simulation program
- (2009) B. R. Brooks et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Pharmacological Characterization of Human Incretin Receptor Missense Variants
- (2009) J.-P. Fortin et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- SOAP: short oligonucleotide alignment program
- (2008) R. Li et al. BIOINFORMATICS
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