Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice
出版年份 2015 全文链接
标题
Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice
作者
关键词
-
出版物
Nature Communications
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-09-23
DOI
10.1038/ncomms9250
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis
- (2014) Julie Charton et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones
- (2014) Juan Pablo Maianti et al. NATURE
- Optimization of Peptide Hydroxamate Inhibitors of Insulin-Degrading Enzyme Reveals Marked Substrate-Selectivity
- (2013) Samer O. Abdul-Hay et al. JOURNAL OF MEDICINAL CHEMISTRY
- Deletion of the Fission Yeast Homologue of Human Insulinase Reveals a TORC1-Dependent Pathway Mediating Resistance to Proteotoxic Stress
- (2013) Clémentine Beuzelin et al. PLoS One
- Proteolytically Inactive Insulin-Degrading Enzyme Inhibits Amyloid Formation Yielding Non-Neurotoxic Aβ Peptide Aggregates
- (2013) Matias B. de Tullio et al. PLoS One
- Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme
- (2013) Lauren A. McCord et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional Relevance of a Novel SlyX Motif in Non-conventional Secretion of Insulin-degrading Enzyme
- (2011) Konstantin Glebov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deletion of Insulin-Degrading Enzyme Elicits Antipodal, Age-Dependent Effects on Glucose and Insulin Tolerance
- (2011) Samer O. Abdul-Hay et al. PLoS One
- Exploring Drug Target Flexibility Usingin SituClick Chemistry: Application to a Mycobacterial Transcriptional Regulator
- (2010) Nicolas Willand et al. ACS Chemical Biology
- Kinetic target-guided synthesis
- (2010) Xiangdong Hu et al. CHEMICAL SOCIETY REVIEWS
- Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin
- (2010) Malcolm A. Leissring et al. PLoS One
- Insulin-Degrading Enzyme: Structure-Function Relationship and its Possible Roles in Health and Disease
- (2009) A. Fernandez-Gamba et al. CURRENT PHARMACEUTICAL DESIGN
- Chitinase inhibitors: extraction of the active framework from natural argifin and use of in situ click chemistry
- (2009) Tomoyasu Hirose et al. JOURNAL OF ANTIBIOTICS
- Molecular Basis of Catalytic Chamber-assisted Unfolding and Cleavage of Human Insulin by Human Insulin-degrading Enzyme
- (2009) Marika Manolopoulou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hydroxamates: Relationships between Structure and Plasma Stability
- (2009) Marion Flipo et al. JOURNAL OF MEDICINAL CHEMISTRY
- Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-α, and Amylin by Human Insulin-Degrading Enzyme
- (2009) Qing Guo et al. JOURNAL OF MOLECULAR BIOLOGY
- Amyloid β-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin
- (2008) E. Malito et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Stem cell antigen-1 localizes to lipid microdomains and associates with insulin degrading enzyme in skeletal myoblasts
- (2008) Conrad L. Epting et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Somatostatin: A Novel Substrate and a Modulator of Insulin-Degrading Enzyme Activity
- (2008) Chiara Ciaccio et al. JOURNAL OF MOLECULAR BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search