Proteolytically Inactive Insulin-Degrading Enzyme Inhibits Amyloid Formation Yielding Non-Neurotoxic Aβ Peptide Aggregates
出版年份 2013 全文链接
标题
Proteolytically Inactive Insulin-Degrading Enzyme Inhibits Amyloid Formation Yielding Non-Neurotoxic Aβ Peptide Aggregates
作者
关键词
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出版物
PLoS One
Volume 8, Issue 4, Pages e59113
出版商
Public Library of Science (PLoS)
发表日期
2013-04-12
DOI
10.1371/journal.pone.0059113
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Insulin-Degrading Enzyme Sorting in Exosomes: A Secretory Pathway for a Key Brain Amyloid-β Degrading Protease
- (2017) Ayelén Bulloj et al. JOURNAL OF ALZHEIMERS DISEASE
- Anion Activation Site of Insulin-degrading Enzyme
- (2011) Nicholas Noinaj et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Relationship between Prion Propensity and the Rates of Individual Molecular Steps of Fibril Assembly
- (2011) Yi-Qian Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Small Heat Shock Proteins Induce a Cerebral Inflammatory Reaction
- (2011) I. B. Bruinsma et al. JOURNAL OF NEUROSCIENCE
- Redox Regulation of Insulin Degradation by Insulin-Degrading Enzyme
- (2011) Crystal M. Cordes et al. PLoS One
- Non-Esterified Fatty Acids Generate Distinct Low-Molecular Weight Amyloid-β (Aβ42) Oligomers along Pathway Different from Fibril Formation
- (2011) Amit Kumar et al. PLoS One
- ANS Binding Reveals Common Features of Cytotoxic Amyloid Species
- (2010) Benedetta Bolognesi et al. ACS Chemical Biology
- Distinct Region-Specific -Synuclein Oligomers in A53T Transgenic Mice: Implications for Neurodegeneration
- (2010) E. Tsika et al. JOURNAL OF NEUROSCIENCE
- The irreversible binding of amyloid peptide substrates to insulin-degrading enzyme
- (2010) Matías B. de Tullio et al. Prion
- Mechanism of amyloid plaque formation suggests an intracellular basis of A pathogenicity
- (2010) R. P. Friedrich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
- (2010) Carol Kilkenny et al. PLOS BIOLOGY
- Mammalian Pitrilysin: Substrate Specificity and Mitochondrial Targeting†
- (2009) K. Martin Chow et al. BIOCHEMISTRY
- Insulin-Degrading Enzyme: Structure-Function Relationship and its Possible Roles in Health and Disease
- (2009) A. Fernandez-Gamba et al. CURRENT PHARMACEUTICAL DESIGN
- Molecular Basis of Catalytic Chamber-assisted Unfolding and Cleavage of Human Insulin by Human Insulin-degrading Enzyme
- (2009) Marika Manolopoulou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Detergent resistant membrane-associated IDE in brain tissue and cultured cells: Relevance to Aβ and insulin degradation
- (2009) Ayelén Bulloj et al. Molecular Neurodegeneration
- Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease
- (2009) Summer L. Bernstein et al. Nature Chemistry
- Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease
- (2008) Alex E. Roher et al. Alzheimers & Dementia
- Protease Activation of α2-Macroglobulin Modulates a Chaperone-like Action with Broad Specificity
- (2008) Katie French et al. BIOCHEMISTRY
- α2-Macroglobulin and Haptoglobin Suppress Amyloid Formation by Interacting with Prefibrillar Protein Species
- (2008) Justin J. Yerbury et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Catalytic Domain of Insulin-degrading Enzyme Forms a Denaturant-resistant Complex with Amyloid β Peptide
- (2008) Ramiro E. Llovera et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hsp104 Targets Multiple Intermediates on the Amyloid Pathway and Suppresses the Seeding Capacity of Aβ Fibrils and Protofibrils
- (2008) Muriel Arimon et al. JOURNAL OF MOLECULAR BIOLOGY
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