Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant

Ryanodine Receptors: Allosteric Ion Channel Giants

(2015) Filip Van Petegem   JOURNAL OF MOLECULAR BIOLOGY

FRET-Based Trilateration of Probes Bound within Functional Ryanodine Receptors

(2014) Bengt Svensson et al.   BIOPHYSICAL JOURNAL

Structure of a mammalian ryanodine receptor

(2014) Ran Zalk et al.   NATURE

Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution

(2014) Zhen Yan et al.   NATURE

Architecture and conformational switch mechanism of the ryanodine receptor

(2014) Rouslan G. Efremov et al.   NATURE

Structural Mapping of Divergent Regions in the Type 1 Ryanodine Receptor Using Fluorescence Resonance Energy Transfer

(2014) Mohana Mahalingam et al.   STRUCTURE

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain

(2014) Kelvin Lau et al.   Nature Communications

Structural insights into the human RyR2 N-terminal region involved in cardiac arrhythmias

(2014) Ľubomír Borko et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

N-terminal and Central Segments of the Type 1 Ryanodine Receptor Mediate Its Interaction with FK506-binding Proteins

(2013) Tanya Girgenrath et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic α-Helix That Transitions to a β-Strand in a Mutant Linked with a Heritable Cardiomyopathy

(2013) Fernando J. Amador et al.   JOURNAL OF MOLECULAR BIOLOGY

Severe congenital RYR1-associated myopathy: The expanding clinicopathologic and genetic spectrum

(2013) D. X. Bharucha-Goebel et al.   NEUROLOGY

Conformational Dynamics inside Amino-Terminal Disease Hotspot of Ryanodine Receptor

(2013) Xiaowei Zhong et al.   STRUCTURE

The Cardiac Ryanodine Receptor N-Terminal Region Contains an Anion Binding Site that Is Targeted by Disease Mutations

(2013) Lynn Kimlicka et al.   STRUCTURE

Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface

(2013) Lynn Kimlicka et al.   Nature Communications

Structural determination of the phosphorylation domain of the ryanodine receptor

(2012) Parveen Sharma et al.   FEBS Journal

Clinical and genetic findings in a large cohort of patients with ryanodine receptor 1 gene-associated myopathies

(2012) Andrea Klein et al.   HUMAN MUTATION

Ryanodine Receptors: Structure and Function

(2012) Filip Van Petegem   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and functional conservation of key domains in InsP3 and ryanodine receptors

(2012) Min-Duk Seo et al.   NATURE

Disease Mutations in the Ryanodine Receptor Central Region: Crystal Structures of a Phosphorylation Hot Spot Domain

(2012) Zhiguang Yuchi et al.   STRUCTURE

Ryanodine Receptor Oxidation Causes Intracellular Calcium Leak and Muscle Weakness in Aging

(2011) Daniel C. Andersson et al.   Cell Metabolism

Localization of the Dantrolene-binding Sequence near the FK506-binding Protein-binding Site in the Three-dimensional Structure of the Ryanodine Receptor

(2011) Ruiwu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structural biology of ryanodine receptors

(2011) Lynn Kimlicka et al.   Science China-Life Sciences

Flexible Architecture of IP3R1 by Cryo-EM

(2011) Steven J. Ludtke et al.   STRUCTURE

The Deletion of Exon 3 in the Cardiac Ryanodine Receptor Is Rescued by β Strand Switching

(2011) Paolo A. Lobo et al.   STRUCTURE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mapping the Ryanodine Receptor FK506-binding Protein Subunit Using Fluorescence Resonance Energy Transfer

(2010) Razvan L. Cornea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule

(2010) Ching-Chieh Tung et al.   NATURE

Multi-minicore disease and atypical periodic paralysis associated with novel mutations in the skeletal muscle ryanodine receptor (RYR1) gene

(2010) Haiyan Zhou et al.   NEUROMUSCULAR DISORDERS

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

(2010) J. Fauconnier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increasing the number of diagnostic mutations in malignant hyperthermia

(2009) Soledad Levano et al.   HUMAN MUTATION

Förster Resonance Energy Transfer Measurements of Ryanodine Receptor Type 1 Structure Using a Novel Site-Specific Labeling Method

(2009) James D. Fessenden   PLoS One

FRET-based mapping of calmodulin bound to the RyR1 Ca2+ release channel

(2009) R. L. Cornea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structures of the N-Terminal Domains of Cardiac and Skeletal Muscle Ryanodine Receptors: Insights into Disease Mutations

(2009) Paolo Antonio Lobo et al.   STRUCTURE

Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating

(2009) Montserrat Samsó et al.   PLOS BIOLOGY

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

(2008) Leonardo G. Trabuco et al.   STRUCTURE