标题
Structure of the EmrE multidrug transporter and its use for inhibitor peptide design
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 34, Pages E7932-E7941
出版商
Proceedings of the National Academy of Sciences
发表日期
2018-08-07
DOI
10.1073/pnas.1802177115
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides
- (2018) Tracy A. Stone et al. BIOORGANIC & MEDICINAL CHEMISTRY
- New free-exchange model of EmrE transport
- (2017) Anne E. Robinson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protonation of a glutamate residue modulates the dynamics of the drug transporter EmrE
- (2016) Anindita Gayen et al. Nature Chemical Biology
- Asymmetric protonation of EmrE
- (2015) Emma A. Morrison et al. JOURNAL OF GENERAL PHYSIOLOGY
- A Structured Loop Modulates Coupling between the Substrate-binding and Dimerization Domains in the Multidrug Resistance Transporter EmrE
- (2014) James R. Banigan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Efflux by Small Multidrug Resistance Proteins Is Inhibited by Membrane-interactive Helix-stapled Peptides
- (2014) Kathrin Bellmann-Sickert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intrinsic Conformational Plasticity of Native EmrE Provides a Pathway for Multidrug Resistance
- (2014) Min-Kyu Cho et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- xMDFF: molecular dynamics flexible fitting of low-resolution X-ray structures
- (2014) Ryan McGreevy et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Targeted conformational search with map-restrained self-guided Langevin dynamics: Application to flexible fitting into electron microscopic density maps
- (2013) Xiongwu Wu et al. JOURNAL OF STRUCTURAL BIOLOGY
- Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus
- (2013) Jun Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Equilibrium Sampling Approach to the Interpretation of Electron Density Maps
- (2013) Andreas Vitalis et al. STRUCTURE
- Stapled Peptides with Improved Potency and Specificity That Activate p53
- (2012) Christopher J. Brown et al. ACS Chemical Biology
- Drug Efflux by a Small Multidrug Resistance Protein Is Inhibited by a Transmembrane Peptide
- (2012) Bradley E. Poulsen et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Antiparallel Dimers of the Small Multidrug Resistance Protein EmrE Are More Stable Than Parallel Dimers
- (2012) Pilar Lloris-Garcerá et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rational Design of Proteolytically Stable, Cell-Permeable Peptide-Based Selective Mcl-1 Inhibitors
- (2012) Avinash Muppidi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Stapled BH3 Peptides against MCL-1: Mechanism and Design Using Atomistic Simulations
- (2012) Thomas L. Joseph et al. PLoS One
- Modulation of Substrate Efflux in Bacterial Small Multidrug Resistance Proteins by Mutations at the Dimer Interface
- (2011) B. E. Poulsen et al. JOURNAL OF BACTERIOLOGY
- Dissecting electrostatic interactions in Bacillus circulans xylanase through NMR-monitored pH titrations
- (2011) Lawrence P. McIntosh et al. JOURNAL OF BIOMOLECULAR NMR
- Structure of the Stapled p53 Peptide Bound to Mdm2
- (2011) Sohee Baek et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Antiparallel EmrE exports drugs by exchanging between asymmetric structures
- (2011) Emma A. Morrison et al. NATURE
- Probing theα-Helical Structural Stability of Stapled p53 Peptides: Molecular Dynamics Simulations and Analysis
- (2010) Zuojun Guo et al. Chemical Biology & Drug Design
- Multidrug Resistance in Bacteria
- (2009) Hiroshi Nikaido Annual Review of Biochemistry
- EmrE, a model for studying evolution and mechanism of ion-coupled transporters
- (2009) Shimon Schuldiner BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- All-Atom Contact Model for Understanding Protein Dynamics from Crystallographic B-Factors
- (2009) Da-Wei Li et al. BIOPHYSICAL JOURNAL
- CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes
- (2009) Sunhwan Jo et al. BIOPHYSICAL JOURNAL
- Diversity and evolution of the small multidrug resistance protein family
- (2009) Denice C Bay et al. BMC EVOLUTIONARY BIOLOGY
- The Assembly Motif of a Bacterial Small Multidrug Resistance Protein
- (2009) Bradley E. Poulsen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ACEMD: Accelerating Biomolecular Dynamics in the Microsecond Time Scale
- (2009) M. J. Harvey et al. Journal of Chemical Theory and Computation
- CHARMM: The biomolecular simulation program
- (2009) B. R. Brooks et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Molecular dynamics flexible fitting: A practical guide to combine cryo-electron microscopy and X-ray crystallography
- (2009) Leonardo G. Trabuco et al. METHODS
- A coordinated network of transporters with overlapping specificities provides a robust survival strategy
- (2009) N. Tal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a Glycine Motif Required for Packing in EmrE, a Multidrug Transporter fromEscherichia coli
- (2008) Yael Elbaz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Small multidrug resistance proteins: A multidrug transporter family that continues to grow
- (2007) Denice C. Bay et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
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