Ligand- and mutation-induced conformational selection in the CCR5 chemokine G protein-coupled receptor
出版年份 2014 全文链接
标题
Ligand- and mutation-induced conformational selection in the CCR5 chemokine G protein-coupled receptor
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 36, Pages 13040-13045
出版商
Proceedings of the National Academy of Sciences
发表日期
2014-08-26
DOI
10.1073/pnas.1413216111
参考文献
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- (2013) R. Berro et al. JOURNAL OF VIROLOGY
- SuperBiHelix method for predicting the pleiotropic ensemble of G-protein-coupled receptor conformations
- (2013) J. K. Bray et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Computationally-predicted CB1 cannabinoid receptor mutants show distinct patterns of salt-bridges that correlate with their level of constitutive activity reflected in G protein coupling levels, thermal stability, and ligand binding
- (2013) Kwang H. Ahn et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex
- (2013) Q. Tan et al. SCIENCE
- Genetically Encoded Photo-cross-linkers Map the Binding Site of an Allosteric Drug on a G Protein-Coupled Receptor
- (2012) Amy Grunbeck et al. ACS Chemical Biology
- Molecular basis for dramatic changes in cannabinoid CB1 G protein-coupled receptor activation upon single and double point mutations
- (2012) Caitlin E. Scott et al. PROTEIN SCIENCE
- Multiple CCR5 Conformations on the Cell Surface Are Used Differentially by Human Immunodeficiency Viruses Resistant or Sensitive to CCR5 Inhibitors
- (2011) R. Berro et al. JOURNAL OF VIROLOGY
- Characterizing and predicting the functional and conformational diversity of seven-transmembrane proteins
- (2011) Ravinder Abrol et al. METHODS
- Predicted structures of agonist and antagonist bound complexes of adenosine A3 receptor
- (2011) Soo-Kyung Kim et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- An Imidazopiperidine Series of CCR5 Antagonists for the Treatment of HIV: The Discovery ofN-{(1S)-1-(3-Fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetamide (PF-232798)
- (2010) Paul A. Stupple et al. JOURNAL OF MEDICINAL CHEMISTRY
- Predicted 3D structures for adenosine receptors bound to ligands: Comparison to the crystal structure
- (2010) William A. Goddard et al. JOURNAL OF STRUCTURAL BIOLOGY
- Elucidation of Binding Sites of Dual Antagonists in the Human Chemokine Receptors CCR2 and CCR5
- (2009) S. E. Hall et al. MOLECULAR PHARMACOLOGY
- Flat-Bottom Strategy for Improved Accuracy in Protein Side-Chain Placements
- (2008) Victor Wai Tak Kam et al. Journal of Chemical Theory and Computation
- Structure of a β1-adrenergic G-protein-coupled receptor
- (2008) Tony Warne et al. NATURE
- The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
- (2008) V.-P. Jaakola et al. SCIENCE
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