Engineering of TEV protease variants by yeast ER sequestration screening (YESS) of combinatorial libraries

Intracellular Detection and Evolution of Site-Specific Proteases Using a Genetic Selection System

(2012) Kathryn D. Verhoeven et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Directed Evolution of Highly Selective Proteases by Using a Novel FACS-Based Screen that Capitalizes on the p53 Regulator MDM2

(2012) Tae Hyeon Yoo et al.   CHEMBIOCHEM

Proteases as therapeutics

(2011) Charles S. Craik et al.   BIOCHEMICAL JOURNAL

Substrate Profiling of Tobacco Etch Virus Protease Using a Novel Fluorescence-Assisted Whole-Cell Assay

(2011) George Kostallas et al.   PLoS One

An overview of enzymatic reagents for the removal of affinity tags

(2011) David S. Waugh   PROTEIN EXPRESSION AND PURIFICATION

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

Activation of Specific Apoptotic Caspases with an Engineered Small-Molecule-Activated Protease

(2010) Daniel C. Gray et al.   CELL

Emerging principles in protease-based drug discovery

(2010) Marcin Drag et al.   NATURE REVIEWS DRUG DISCOVERY

Engineering next generation proteases

(2009) Mark Pogson et al.   CURRENT OPINION IN BIOTECHNOLOGY

Proteases That Can Distinguish among Different Post-translational Forms of Tyrosine Engineered Using Multicolor Flow Cytometry

(2009) Navin Varadarajan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In the light of directed evolution: Pathways of adaptive protein evolution

(2009) J. D. Bloom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Engineered Protease that Cleaves Specifically after Sulfated Tyrosine

(2008) Navin Varadarajan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering of protease variants exhibiting altered substrate specificity

(2008) Saravanan Sellamuthu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

(2008) Oliver Schilling et al.   NATURE BIOTECHNOLOGY

Highly active and selective endopeptidases with programmed substrate specificities

(2008) Navin Varadarajan et al.   Nature Chemical Biology