Directed Evolution of Highly Selective Proteases by Using a Novel FACS-Based Screen that Capitalizes on the p53 Regulator MDM2

Novel Fluorescence-Assisted Whole-Cell Assay for Engineering and Characterization of Proteases and Their Substrates

(2010) G. Kostallas et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Proteases That Can Distinguish among Different Post-translational Forms of Tyrosine Engineered Using Multicolor Flow Cytometry

(2009) Navin Varadarajan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX

(2009) M. Pazgier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Engineered Protease that Cleaves Specifically after Sulfated Tyrosine

(2008) Navin Varadarajan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering of protease variants exhibiting altered substrate specificity

(2008) Saravanan Sellamuthu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Global Sequencing of Proteolytic Cleavage Sites in Apoptosis by Specific Labeling of Protein N Termini

(2008) Sami Mahrus et al.   CELL

Highly active and selective endopeptidases with programmed substrate specificities

(2008) Navin Varadarajan et al.   Nature Chemical Biology