UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling

TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis

(2013) Boyi Liu et al.   FASEB JOURNAL

NFIB is a governor of epithelial–melanocyte stem cell behaviour in a shared niche

(2013) Chiung-Ying Chang et al.   NATURE

Temporomandibular joint pain: A critical role for Trpv4 in the trigeminal ganglion

(2013) Yong Chen et al.   PAIN

UV light phototransduction activates transient receptor potential A1 ion channels in human melanocytes

(2013) N. W. Bellono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cells and Circuitry for Itch Responses in Mice

(2013) S. K. Mishra et al.   SCIENCE

An oral TRPV1 antagonist attenuates laser radiant-heat-evoked potentials and pain ratings from UVB-inflamed and normal skin

(2012) Klaus Schaffler et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair

(2012) Catherine P. Lu et al.   CELL

Gene Profiling of Narrowband UVB–Induced Skin Injury Defines Cellular and Molecular Innate Immune Responses

(2012) Milène Kennedy Crispin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Rodents Rely on Merkel Cells for Texture Discrimination Tasks

(2012) S. M. Maricich et al.   JOURNAL OF NEUROSCIENCE

Ultraviolet radiation damages self noncoding RNA and is detected by TLR3

(2012) Jamie J Bernard et al.   NATURE MEDICINE

Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration

(2011) Piul Rabbani et al.   CELL

TRPV4 Agonists and Antagonists

(2011) Fabien Vincent et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

TRPV4-Mediated Calcium Influx into Human Bronchial Epithelia upon Exposure to Diesel Exhaust Particles

(2011) Jinju Li et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Transient receptor potential channels as therapeutic targets

(2011) Magdalene M. Moran et al.   NATURE REVIEWS DRUG DISCOVERY

Pirt, a TRPV1 Modulator, Is Required for Histamine-Dependent and -Independent Itch

(2011) Kush N. Patel et al.   PLoS One

CXCL5 Mediates UVB Irradiation-Induced Pain

(2011) J. M. Dawes et al.   Science Translational Medicine

TRPM8: From Cold to Cancer, Peppermint to Pain

(2010) Wendy M. Knowlton et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Identification of epidermal progenitors for the Merkel cell lineage

(2010) S.-H. Woo et al.   DEVELOPMENT

TRPV1-lineage neurons are required for thermal sensation

(2010) Santosh K Mishra et al.   EMBO JOURNAL

The TRPV4 Channel Contributes to Intercellular Junction Formation in Keratinocytes

(2010) Takaaki Sokabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin-6: a local pain trigger?

(2010) Camilla I Svensson   ARTHRITIS RESEARCH & THERAPY

TRPV1-mediated itch in seasonal allergic rhinitis

(2009) L. Alenmyr et al.   ALLERGY

Finding One's Niche in the Skin

(2009) Elaine Fuchs   Cell Stem Cell

Screening TRPV1 antagonists for the treatment of pain: lessons learned over a decade

(2009) József Lázár et al.   Expert Opinion on Drug Discovery

The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli

(2009) Stuart M. Brierley et al.   GASTROENTEROLOGY

Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis

(2009) Alexandra Van Keymeulen et al.   JOURNAL OF CELL BIOLOGY

Non-Neuronal Expression of Transient Receptor Potential Type A1 (TRPA1) in Human Skin

(2009) Ruzanna Atoyan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Novel Repression of Kcc2 Transcription by REST-RE-1 Controls Developmental Switch in Neuronal Chloride

(2009) M. Yeo et al.   JOURNAL OF NEUROSCIENCE

Ablation of TrpV1 neurons reveals their selective role in thermal pain sensation

(2009) Santosh K. Mishra et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms

(2009) N. Imamachi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Merkel Cells Are Essential for Light-Touch Responses

(2009) S. M. Maricich et al.   SCIENCE

The role of TRPV1 receptors in pain evoked by noxious thermal and chemical stimuli

(2009) William D. Willis   EXPERIMENTAL BRAIN RESEARCH

Stress-Induced Neurogenic Inflammation in Murine Skin Skews Dendritic Cells Towards Maturation and Migration

(2008) Ricarda Alcira Joachim et al.   AMERICAN JOURNAL OF PATHOLOGY

Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia

(2008) Walter E. B. Sipe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Interleukin-1 signaling is required for induction and maintenance of postoperative incisional pain: Genetic and pharmacological studies in mice

(2008) Gilly Wolf et al.   BRAIN BEHAVIOR AND IMMUNITY

Ultraviolet light and photosensitising agents activate TRPA1 via generation of oxidative stress

(2008) Kerstin Hill et al.   CELL CALCIUM

Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway

(2008) Martin J. Gunthorpe et al.   DRUG DISCOVERY TODAY

A new tr(i)p to sense pain: TRPA1 channel as a target for novel analgesics

(2008) Xinjiang Cai   Expert Review of Neurotherapeutics

Endothelin Receptors and Pain

(2008) Alla Khodorova et al.   JOURNAL OF PAIN

Association of catastrophizing with interleukin-6 responses to acute pain

(2008) Robert R. Edwards et al.   PAIN

Endothelin1 activates and sensitizes human C-nociceptors

(2007) Barbara Namer et al.   PAIN