Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities

CDK8 Maintains Tumor Dedifferentiation and Embryonic Stem Cell Pluripotency

(2012) A. S. Adler et al.   CANCER RESEARCH

Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome

(2011) Kristin A. D. Sauter et al.   CANCER BIOLOGY & THERAPY

Identification of target genes for the CDK subunits of the Mediator complex

(2011) Taiki Tsutsui et al.   GENES TO CELLS

Dysregulation of CDK8 and Cyclin C in tumorigenesis

(2011) Wu Xu et al.   Journal of Genetics and Genomics

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

DNA Damage-Mediated Induction of a Chemoresistant Niche

(2010) Luke A. Gilbert et al.   CELL

CDK19 is disrupted in a female patient with bilateral congenital retinal folds, microcephaly and mild mental retardation

(2010) Arijit Mukhopadhyay et al.   HUMAN GENETICS

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

(2010) Avnish Kapoor et al.   NATURE

CDK8 is a positive regulator of transcriptional elongation within the serum response network

(2010) Aaron J Donner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nucleolar Disruption Ensures Nuclear Accumulation of p21 upon DNA Damage

(2010) Neus Abella et al.   TRAFFIC

Stereodivergent Synthesis of 17-α and 17-β-Aryl Steroids: Application and Biological Evaluation of D-Ring Cortistatin Analogues

(2009) Jun Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cortistatin A is a High-Affinity Ligand of Protein Kinases ROCK, CDK8, and CDK11

(2009) Victor J. Cee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

(2009) Claudio Alarcón et al.   CELL

Cyclin-dependent kinases: a family portrait

(2009) Marcos Malumbres et al.   NATURE CELL BIOLOGY

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Rapid Chemotherapy-Induced Acute Endothelial Progenitor Cell Mobilization: Implications for Antiangiogenic Drugs as Chemosensitizing Agents

(2008) Yuval Shaked et al.   CANCER CELL

Induction of Cancer Metastasis by Cyclophosphamide Pretreatment of Host Mice: An Opposite Effect of Chemotherapy

(2008) K. Yamauchi et al.   CANCER RESEARCH

P53 mutations in stromal fibroblasts sensitize tumors against chemotherapy

(2008) Daniel Lafkas et al.   INTERNATIONAL JOURNAL OF CANCER

Chemotherapeutic drugs and human tumor cells cytokine network

(2008) Vera Levina et al.   INTERNATIONAL JOURNAL OF CANCER

E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8

(2008) Erick J. Morris et al.   NATURE

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

(2008) Ron Firestein et al.   NATURE

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY