Synthesis and anti-cancer screening of novel heterocyclic-(2H)-1,2,3-triazoles as potential anti-cancer agents
出版年份 2015 全文链接
标题
Synthesis and anti-cancer screening of novel heterocyclic-(2H)-1,2,3-triazoles as potential anti-cancer agents
作者
关键词
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出版物
MedChemComm
Volume 6, Issue 8, Pages 1535-1543
出版商
Royal Society of Chemistry (RSC)
发表日期
2015-06-30
DOI
10.1039/c5md00219b
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Comparison of crystal structures of 4-(benzo[b]thiophen-2-yl)-5-(3,4,5-trimethoxyphenyl)-2H-1,2,3-triazole and 4-(benzo[b]thiophen-2-yl)-2-methyl-5-(3,4,5-trimethoxyphenyl)-2H-1,2,3-triazole
- (2014) Narsimha Reddy Penthala et al. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
- An Organocatalytic Azide-Aldehyde [3+2] Cycloaddition: High-Yielding Regioselective Synthesis of 1,4-Disubstituted 1,2,3-Triazoles
- (2014) Dhevalapally B. Ramachary et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Design and synthesis of pironetin analogue/combretastatin A-4 hybrids containing a 1,2,3-triazole ring and evaluation of their cytotoxic activity
- (2014) Concepción Vilanova et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Ce(OTf)3-Catalyzed [3 + 2] Cycloaddition of Azides with Nitroolefins: Regioselective Synthesis of 1,5-Disubstituted 1,2,3-Triazoles
- (2014) Ying-Chun Wang et al. JOURNAL OF ORGANIC CHEMISTRY
- DISRUPT: A randomised phase 2 trial of ombrabulin (AVE8062) plus a taxane–platinum regimen as first-line therapy for metastatic non-small cell lung cancer
- (2014) Joachim von Pawel et al. LUNG CANCER
- l-Proline catalyzed one-step synthesis of 4,5-diaryl-2H-1,2,3-triazoles from heteroaryl cyanostilbenes via [3+2]cycloaddition of azide
- (2014) Narsimha Reddy Penthala et al. TETRAHEDRON LETTERS
- Preparation of 4,5 disubstituted-2H-1,2,3-triazoles from (Z)-2,3-diaryl substituted acrylonitriles
- (2014) Nikhil Reddy Madadi et al. TETRAHEDRON LETTERS
- Synthesis and evaluation of a series of quinolinyl trans-cyanostilbene analogs as anticancer agents
- (2014) Narsimha Reddy Penthala et al. MedChemComm
- Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines
- (2013) Dmitry V. Demchuk et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and anti-proliferative activity of aromatic substituted 5-((1-benzyl-1H-indol-3-yl)methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione analogs against human tumor cell lines
- (2013) Nikhil Reddy Madadi et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Crenolanib is active against models of drug-resistant FLT3-ITD-positive acute myeloid leukemia
- (2013) E. I. Zimmerman et al. BLOOD
- Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents
- (2013) Narsimha Reddy Penthala et al. MedChemComm
- Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A–1
- (2012) Thomas M. Beale et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Phase I Trial of Combretastatin A4 Phosphate (CA4P) in Combination with Bevacizumab in Patients with Advanced Cancer
- (2012) P. Nathan et al. CLINICAL CANCER RESEARCH
- The vascular disrupting agent ombrabulin (AVE8062) enhances the efficacy of standard therapies in head and neck squamous cell carcinoma xenograft models
- (2012) Céline Clémenson et al. INVESTIGATIONAL NEW DRUGS
- Thyroidectomy followed by fosbretabulin (CA4P) combination regimen appears to suggest improvement in patient survival in anaplastic thyroid cancer
- (2012) Julie A. Sosa et al. SURGERY
- Synthesis, biological evaluation and molecular modeling of 1,2,3-triazole analogs of combretastatin A-1
- (2011) Øyvind W. Akselsen et al. BIOORGANIC & MEDICINAL CHEMISTRY
- 1,2,3-Triazole analogs of combretastatin A-4 as potential microtubule-binding agents
- (2010) Kristin Odlo et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Leukemia regression by vascular disruption and antiangiogenic therapy
- (2010) G. J. Madlambayan et al. BLOOD
- Synthesis and Antitumor Activity of 1,5-Disubstituted 1,2,4-Triazoles as Cis-Restricted Combretastatin Analogues
- (2010) Romeo Romagnoli et al. JOURNAL OF MEDICINAL CHEMISTRY
- BNC105: A Novel Tubulin Polymerization Inhibitor That Selectively Disrupts Tumor Vasculature and Displays Single-Agent Antitumor Efficacy
- (2010) G. Kremmidiotis et al. MOLECULAR CANCER THERAPEUTICS
- Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin
- (2009) G. Kuznetsov et al. MOLECULAR CANCER THERAPEUTICS
- 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin
- (2008) Kristin Odlo et al. BIOORGANIC & MEDICINAL CHEMISTRY
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