Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerability
出版年份 2015 全文链接
标题
Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerability
作者
关键词
-
出版物
Frontiers in Cellular Neuroscience
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2015-06-16
DOI
10.3389/fncel.2015.00225
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Calcium binding to gatekeeper residues flanking aggregation-prone segments underlies non-fibrillar amyloid traits in superoxide dismutase 1 (SOD1)
- (2015) Sílvia G. Estácio et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis
- (2014) Mayuko Osaka et al. HUMAN MOLECULAR GENETICS
- TDP-43 Toxicity Proceeds via Calcium Dysregulation and Necrosis in Aging Caenorhabditis elegans Motor Neurons
- (2014) D. Aggad et al. JOURNAL OF NEUROSCIENCE
- Genetic heterogeneity of amyotrophic lateral sclerosis: Implications for clinical practice and research
- (2014) Xiaowei W. Su et al. MUSCLE & NERVE
- Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis
- (2014) Janel O Johnson et al. NATURE NEUROSCIENCE
- Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury
- (2014) M.-D. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis
- (2014) Vedrana Tadic et al. Frontiers in Cellular Neuroscience
- ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43
- (2014) Radu Stoica et al. Nature Communications
- Protein aggregation in amyotrophic lateral sclerosis
- (2013) Anna M. Blokhuis et al. ACTA NEUROPATHOLOGICA
- Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro
- (2013) Paolo Convertini et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients
- (2013) Takenari Yamashita et al. BRAIN RESEARCH
- Calcium-dependent protein folding in amyotrophic lateral sclerosis
- (2013) Tino Prell et al. CELL CALCIUM
- Overexpression of human mutated G93A SOD1 changes dynamics of the ER mitochondria calcium cycle specifically in mouse embryonic motor neurons
- (2013) Janin Lautenschläger et al. EXPERIMENTAL NEUROLOGY
- Calcium Ions Promote Superoxide Dismutase 1 (SOD1) Aggregation into Non-fibrillar Amyloid
- (2013) Sónia S. Leal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis
- (2013) Julie D. Atkin et al. JOURNAL OF NEUROCHEMISTRY
- Amyotrophic lateral sclerosis: an update on recent genetic insights
- (2013) Yohei Iguchi et al. JOURNAL OF NEUROLOGY
- Enhancing Mitochondrial Calcium Buffering Capacity Reduces Aggregation of Misfolded SOD1 and Motor Neuron Cell Death without Extending Survival in Mouse Models of Inherited Amyotrophic Lateral Sclerosis
- (2013) P. A. Parone et al. JOURNAL OF NEUROSCIENCE
- Loss of calretinin- and parvalbumin-immunoreactive axons in anterolateral columns beyond the corticospinal tracts of amyotrophic lateral sclerosis spinal cords
- (2013) Shintaro Hayashi et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Taking a risk: a therapeutic focus on ataxin-2 in amyotrophic lateral sclerosis?
- (2013) Dianne M.A. van den Heuvel et al. TRENDS IN MOLECULAR MEDICINE
- Calcium, mitochondria, and the pathogenesis of ALS: the good, the bad, and the ugly
- (2013) Manoj Kumar Jaiswal Frontiers in Cellular Neuroscience
- The genetics and neuropathology of amyotrophic lateral sclerosis
- (2012) Ammar Al-Chalabi et al. ACTA NEUROPATHOLOGICA
- Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
- (2012) G. M. Morotz et al. HUMAN MOLECULAR GENETICS
- Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis
- (2012) Manal A. Farg et al. HUMAN MOLECULAR GENETICS
- Roles of Ataxin-2 in Pathological Cascades Mediated by TAR DNA-binding Protein 43 (TDP-43) and Fused in Sarcoma (FUS)
- (2012) Yoshihiro Nihei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Calcium/Calmodulin-dependent Protein Kinase II (CaMKII) Inhibition Induces Neurotoxicity via Dysregulation of Glutamate/Calcium Signaling and Hyperexcitability
- (2012) Nicole M. Ashpole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis
- (2012) Chi-Hong Wu et al. NATURE
- Aberrant Localization of FUS and TDP43 Is Associated with Misfolding of SOD1 in Amyotrophic Lateral Sclerosis
- (2012) Edward Pokrishevsky et al. PLoS One
- VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
- (2011) Kurt J. De Vos et al. HUMAN MOLECULAR GENETICS
- Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: Mechanistic relationship and differential sensitivity to intervention
- (2011) Miranda L. Tradewell et al. NEUROBIOLOGY OF DISEASE
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- Mitochondrial dysfunction in ALS
- (2011) Mauro Cozzolino et al. PROGRESS IN NEUROBIOLOGY
- FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis
- (2010) Han-Xiang Deng et al. ANNALS OF NEUROLOGY
- Calcium Dysregulation and Homeostasis of Neural Calcium in the Molecular Mechanisms of Neurodegenerative Diseases Provide Multiple Targets for Neuroprotection
- (2010) Gregor Zündorf et al. ANTIOXIDANTS & REDOX SIGNALING
- Calcium dysregulation in amyotrophic lateral sclerosis
- (2010) Julian Grosskreutz et al. CELL CALCIUM
- Deranged Calcium Signaling in Purkinje Cells and Pathogenesis in Spinocerebellar Ataxia 2 (SCA2) and Other Ataxias
- (2010) Adebimpe Kasumu et al. CEREBELLUM
- ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2
- (2010) Steve Pedrini et al. HUMAN MOLECULAR GENETICS
- Structural Requirements for VAP-B Oligomerization and Their Implication in Amyotrophic Lateral Sclerosis-associated VAP-B(P56S) Neurotoxicity
- (2010) SoHui Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial dysfunction and intracellular calcium dysregulation in ALS
- (2010) Hibiki Kawamata et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
- (2010) Andrew C. Elden et al. NATURE
- Mutations of optineurin in amyotrophic lateral sclerosis
- (2010) Hirofumi Maruyama et al. NATURE
- Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS
- (2010) Janel O. Johnson et al. NEURON
- Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology
- (2010) E.L. Tudor et al. NEUROSCIENCE
- Novel Antibodies Reveal Inclusions Containing Non-Native SOD1 in Sporadic ALS Patients
- (2010) Karin Forsberg et al. PLoS One
- Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS)
- (2009) Kathryn Volkening et al. BRAIN RESEARCH
- Deranged Calcium Signaling and Neurodegeneration in Spinocerebellar Ataxia Type 2
- (2009) J. Liu et al. JOURNAL OF NEUROSCIENCE
- TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations
- (2009) Satomi Maekawa et al. NEUROPATHOLOGY
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
- FFAT rescues VAPA-mediated inhibition of ER-to-Golgi transport and VAPB-mediated ER aggregation
- (2008) D. C. Prosser et al. JOURNAL OF CELL SCIENCE
- Deranged Calcium Signaling and Neurodegeneration in Spinocerebellar Ataxia Type 3
- (2008) X. Chen et al. JOURNAL OF NEUROSCIENCE
- Cu/Zn Superoxide Dismutase Typical for Familial Amyotrophic Lateral Sclerosis Increases the Vulnerability of Mitochondria and Perturbs Ca2+ Homeostasis in SOD1G93A Mice
- (2008) M. K. Jaiswal et al. MOLECULAR PHARMACOLOGY
- Molecular interaction of neurocalcin α with alsin (ALS2)
- (2008) Toshinori Masutani et al. NEUROSCIENCE LETTERS
- Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria
- (2008) C. Vande Velde et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
- Parvalbumin overexpression alters immune-mediated increases in intracellular calcium, and delays disease onset in a transgenic model of familial amyotrophic lateral sclerosis
- (2003) David R. Beers et al. JOURNAL OF NEUROCHEMISTRY
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