Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
出版年份 2012 全文链接
标题
Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
作者
关键词
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出版物
HUMAN MOLECULAR GENETICS
Volume 21, Issue 9, Pages 1979-1988
出版商
Oxford University Press (OUP)
发表日期
2012-01-19
DOI
10.1093/hmg/dds011
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- (2011) Kieran Brickley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1
- (2011) A. Vagnoni et al. JOURNAL OF CELL SCIENCE
- Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis
- (2011) Laura Ferraiuolo et al. Nature Reviews Neurology
- Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: Mechanistic relationship and differential sensitivity to intervention
- (2011) Miranda L. Tradewell et al. NEUROBIOLOGY OF DISEASE
- Calcium dysregulation in amyotrophic lateral sclerosis
- (2010) Julian Grosskreutz et al. CELL CALCIUM
- Structural Requirements for VAP-B Oligomerization and Their Implication in Amyotrophic Lateral Sclerosis-associated VAP-B(P56S) Neurotoxicity
- (2010) SoHui Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of the Properties of a Novel Mutation in VAPB in Familial Amyotrophic Lateral Sclerosis
- (2010) Han-Jou Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AAV-mediated expression of wild-type and ALS-linked mutant VAPB selectively triggers death of motoneurons through a Ca2+-dependent ER-associated pathway
- (2010) Karine Langou et al. JOURNAL OF NEUROCHEMISTRY
- Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology
- (2010) E.L. Tudor et al. NEUROSCIENCE
- Deficits in axonal transport precede ALS symptoms in vivo
- (2010) L. G. Bilsland et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial Motility
- (2009) Xinnan Wang et al. CELL
- A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum
- (2009) Elisa Fasana et al. FASEB JOURNAL
- Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis
- (2009) Gang Li et al. JOURNAL OF CELL BIOLOGY
- Workshop 3
- (2009) JOURNAL OF NEUROCHEMISTRY
- ER Stress and Unfolded Protein Response in Amyotrophic Lateral Sclerosis
- (2009) Kohsuke Kanekura et al. MOLECULAR NEUROBIOLOGY
- A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice
- (2009) Smita Saxena et al. NATURE NEUROSCIENCE
- Miro1 Is a Calcium Sensor for Glutamate Receptor-Dependent Localization of Mitochondria at Synapses
- (2009) Andrew F. MacAskill et al. NEURON
- Role of Axonal Transport in Neurodegenerative Diseases
- (2008) Kurt J. De Vos et al. Annual Review of Neuroscience
- The Amyotrophic Lateral Sclerosis 8 Protein VAPB Is Cleaved, Secreted, and Acts as a Ligand for Eph Receptors
- (2008) Hiroshi Tsuda et al. CELL
- VAPB interacts with and modulates the activity of ATF6
- (2008) C. Gkogkas et al. HUMAN MOLECULAR GENETICS
- FFAT rescues VAPA-mediated inhibition of ER-to-Golgi transport and VAPB-mediated ER aggregation
- (2008) D. C. Prosser et al. JOURNAL OF CELL SCIENCE
- ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB
- (2008) Hiroaki Suzuki et al. JOURNAL OF NEUROCHEMISTRY
- Coordinated Lipid Transfer between the Endoplasmic Reticulum and the Golgi Complex Requires the VAP Proteins and Is Essential for Golgi-mediated Transport
- (2008) Diego Peretti et al. MOLECULAR BIOLOGY OF THE CELL
- New VAPB deletion variant and exclusion of VAPB mutations in familial ALS
- (2008) J. E. Landers et al. NEUROLOGY
- A Drosophila Model of ALS: Human ALS-Associated Mutation in VAP33A Suggests a Dominant Negative Mechanism
- (2008) Anuradha Ratnaparkhi et al. PLoS One
- Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase
- (2008) M. Saotome et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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