Article
Chemistry, Multidisciplinary
Puneet Singh Gahlaut, Deepak Gautam, Prem Lama, Barun Jana
Summary: A modified click reaction between 2-azidopyridine and di(prop-2-yn-1-yl)phthalate produces a novel bis(1,2,3-triazolyl-pyridine) ligand on an ortho-phthalic acid platform. The ligand can form transition metal complexes through selective N-3 coordination. The formed PdCl2[bptmp] complex acts as a highly effective catalyst for the Suzuki-Miyaura coupling reaction in a water/ethanol solvent combination.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Fulai Hao, Xinying Miao, Manman Zhang, Zhen Dong, Maolin Zhai, Yanbai Shen, Jianhua Zu, Jun Yang, Long Zhao
Summary: In this study, a poly(ionic liquid) gel containing an imidazole group was fabricated and demonstrated high adsorption efficiency and selectivity for Au(iii), Pt(iv), and Pd(ii) ions in a wide pH range.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Alessandro Di Girolamo, Filippo Monti, Andrea Mazzanti, Elia Matteucci, Nicola Armaroli, Letizia Sambri, Andrea Baschieri
Summary: This study successfully synthesized five cationic iridium(III) complexes using phenyl-triazole derivatives, including the less explored tris-heteroleptic analogues. The redox and emission properties of the complexes can be effectively tuned by different ligands. The complexes equipped with bipyridine ancillary ligand exhibit reversible redox processes and high emission quantum yields, while the complexes equipped with high-field isocyanide ligands display irreversible redox processes and high-energy emission with low quantum yields.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Dominik Moreth, Gerald Hoerner, Victoria V. L. Mueller, Lucia Geyer, Ulrich Schatzschneider
Summary: This study investigates the structure and reactivity of a series of cyclometalated azido complexes through X-ray diffraction analysis and NMR spectroscopy. The reaction rate is found to be positively correlated with the charge density of the metal ion, and the substituents on the alkyne affect the reaction kinetics. Crystal structure analysis reveals different coordination modes of the complexes, unaffected by the substituents on the alkyne. Additionally, the study demonstrates the feasibility of biofunctionalizing metal complexes through the iClick reaction.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Elzbieta Radzyminska-Lenarcik, Ilona Pyszka, Artur Kosciuszko
Summary: This study demonstrates that a new amine derivative EDAB-acac can effectively separate a mixture containing Au(III), Pd(II), and Pt(IV) ions in an acidic medium (HCl) using solvent extraction. The impact of acid concentration and solvent type on separation efficiency was discussed, with high donor number solvents enhancing extraction. A 3-step stripping process for the recovery of Pd(II), Au(III), and Pt(IV) from the mixture was proposed, making it useful for e-waste recycling.
Article
Chemistry, Multidisciplinary
Qi Wu, Changfeng Zhao, Qinzhong Wang, Jing Liu
Summary: This study proposes an efficient separation of Au(iii)/Pd(ii)/Pt(iv)/Rh(iii) using a cloud point extraction system with 2-mercaptobenzothiazole-functionalised ionic liquid ([C(6)mim][2MBT]). The direct cloud point extraction of Au(iii) was achieved without any functionalised ionic liquids. Addition of [C(6)mim][2MBT] greatly enhanced the extraction performance of Pd(ii). However, preconcentration of Pt(iv) and Rh(iii) required the addition of stannous chloride, which can be adjusted by changing the hydrochloric acid concentration.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Pavel S. Gribanov, Anna N. Philippova, Maxim A. Topchiy, Lidiya Minaeva, Andrey F. Asachenko, Sergey N. Osipov
Summary: An efficient method for accessing novel 5-(het)arylamino-1,2,3-triazole derivatives has been developed using Buchwald-Hartwig cross-coupling reaction. The most active catalyst for the process, palladium complex [(THP-Dipp)Pd(cinn)Cl] with expanded-ring N-heterocyclic carbene ligand, affords the target molecules in high yields.
Article
Chemistry, Multidisciplinary
Ali Reza Sardarian, Fatemeh Abbasi, Mohsen Esmaeilpour
Summary: In this paper, Fe3O4@Zein-Cu(II) NPs were synthesized and used as a reusable magnetic catalyst for Cu-catalyzed azide-alkyne cycloaddition reactions. The catalyst showed excellent catalytic activity and selectivity in the regioselective click preparation of fluorescent 1,4-disubstituted-1,2,3-triazoles. It exhibited good magnetism, allowing easy recovery and reuse for multiple runs without significant loss in activity.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Article
Chemistry, Organic
Xinzhe Shi, Jian Zhang, Thierry Roisnel, Jean-Francois Soule, Henri Doucet
Summary: The reactivity of 2-benzyl-1,2,3-triazole in palladium-catalyzed direct arylation was investigated, leading to the selective synthesis of 2-benzyl-4-aryl-1,2,3-triazoles and subsequent synthesis of 4,5-diarylated 2-benzyl-1,2,3-triazoles. This selective 4,5-diarylation was successfully applied for the synthesis of pi-extended polycyclic heteroaromatic structures phenanthro[9,10-d][1,2,3]triazoles through Pd-catalyzed C4- and C5-intermolecular arylations followed by Pd-catalyzed C-H intramolecular arylation.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Review
Chemistry, Inorganic & Nuclear
Konrad Kowalski
Summary: Cancer is a leading cause of death worldwide. This review emphasizes the significance of metal-catalyzed azide-alkyne cycloaddition reactions in synthesizing ferrocenyl-x-1,2,3-triazolyl-R compounds with anticancer activity. The review discusses over 160 ferrocenyl-triazoles and their classification into four categories based on their chemical properties. The study demonstrates that copper-catalyzed azide-alkyne cycloaddition reactions are particularly important in yielding the highest number of ferrocenyl-x-1,2,3-triazolyl compounds with anticancer activity. Oxidative stress and reactive oxygen species generation are identified as common mechanisms through which the ferrocenyl moiety contributes to the anticancer activity of 1,2,3-triazolyl derivatives. The review contains 23 figures, 24 schemes, and 208 references.(c) 2022 Elsevier B.V. All rights reserved.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Chemistry, Organic
Avetik G. Gevondian, Yury N. Kotovshchikov, Gennadij Latyshev, Nikolay Lukashev, Irina P. Beletskaya
Summary: A straightforward domino approach has been developed for the assembly of benzoxazole-derived sulfonamides, based on the in situ generation of diazo compounds from readily available starting material followed by denitrogenative transformation. The method is operationally simple, with a broad substrate scope and generally good yields, providing a library of target compounds.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Physical
Zita G. Rios-Malvaez, Ma-Angeles Cano-Herrera, Juan Carlos Davila-Becerril, Gustavo Mondragon-Solorzano, Maria Teresa Ramirez-Apan, David Morales-Morales, Joaquin Barroso-Flores, Jonnathan G. Santillan-Benitez, M. V. Basavanag Unnamatla, Marco Antonio Garcia-Eleno, Nelly Gonzalez-Rivas, Erick Cuevas-Yanez
Summary: A novel series of 4-(1,2,3-triazol-1-yl) salicylic acid derivatives were synthesized and their selective activity against various tumoral cell lines was explored in vitro. Molecular docking studies suggested a strong interaction between some compounds and ARG-154 in STAT3.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Biochemistry & Molecular Biology
Francesca Begini, Renata A. Balaguez, Allya Larroza, Eric F. Lopes, Eder Joao Lenardao, Claudio Santi, Diego Alves
Summary: This study presents a simple method to synthesize 4-arylselanyl-1H-1,2,3-triazoles from selenium-containing carbinols in a one-pot strategy, with moderate to good yields including quinoline and Zidovudine derivatives. One-pot protocols are essential for addressing concerns about waste production and solvent consumption, while also producing interesting by-products with alkynylselenium moieties connected to the triazole.
Article
Engineering, Environmental
Akash Kumar, Shruti Verma, Devendra Deo Pathak
Summary: A new graphene oxide-supported Cu(II) Schiff base complex was synthesized and found to be highly efficient in click reactions and the synthesis of 2H-indazoles, showcasing the catalyst's excellent performance in terms of efficiency and environmental friendliness.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Inorganic & Nuclear
Nasrin Moeini-Eghbali, Hossein Eshghi
Summary: In this study, a new and selective nanocatalyst (Fe3O4@S-TiO2/Cu) was synthesized by incorporating sulfur heteroatoms onto Fe3O4@TiO2 substrate as a ligand to stabilize copper nanoparticles. The Fe3O4@S-TiO2/Cu nanorods were characterized using various techniques and showed high catalytic activity in preparing triazole derivatives. The nanocatalyst exhibited advantages such as high regioselectivity, short reaction times, easy separation, and recyclability.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Roan A. S. Vasdev, James A. Findlay, David R. Turner, James D. Crowley
Summary: A new ferrocene-containing self-assembled double-walled triangle structure has been synthesized and characterized, showing interactions with anionic guest and redox activity without influence from the guest.
CHEMISTRY-AN ASIAN JOURNAL
(2021)
Article
Chemistry, Inorganic & Nuclear
Tasha R. Steel, Kelvin K. H. Tong, Tilo Sohnel, Stephen M. F. Jamieson, L. James Wright, James D. Crowley, Muhammad Hanif, Christian G. Hartinger
Summary: Multimetallic complexes have been synthesized and characterized, with studies conducted on their binding properties with DNA and protein models. The anticancer activity of the complexes was evaluated against cancer cell lines, showing moderate antiproliferative effects.
INORGANICA CHIMICA ACTA
(2021)
Article
Chemistry, Inorganic & Nuclear
Daniel A. W. Ross, Joseph Mapley, Andrew P. Cording, Roan A. S. Vasdev, C. John McAdam, Keith C. Gordon, James D. Crowley
Summary: A bulky 6,6'-diTPAbpy ligand was synthesized and used to form homoleptic complexes with Cu(I) and Ag(I) ions, as well as interact with 6-coordinate metal ions. The steric bulk of the ligand affected the coordination geometry and photophysical properties of the complexes, showing changes in absorption and emission properties.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Joshua J. Sutton, Dan Preston, Philipp Traber, Johannes Steinmetzer, Xue Wu, Surajit Kayal, Xue-Z Sun, James D. Crowley, Michael W. George, Stephan Kupfer, Keith C. Gordon
Summary: The optical properties of two Re(CO)(3)(bpy)Cl complexes with different substituents were studied, revealing distinct charge transfer bands in their absorption spectra and two emissive states in their excited-state spectroscopy which are modulated by solvent. Time-resolved infrared spectroscopy identified the nature of the excited states in different solvents, with DFT calculations suggesting that the switching of properties induced by solvent is controlled by spin-orbit coupling.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Lynn S. Lisboa, Mie Riisom, Roan A. S. Vasdev, Stephen M. F. Jamieson, L. James Wright, Christian G. Hartinger, James D. Crowley
Summary: Two new di(2,2'-bipyridine) ligands were synthesized to generate metallosupramolecular cylinders, which were characterized through various spectroscopic techniques. The cylinders crystallized as racemic mixtures of helicates and showed anticancer activity against different cell lines, with potential differences in modes of action compared to standard treatments like cisplatin.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Lynn S. Lisboa, Dan Preston, C. John McAdam, L. James Wright, Christian G. Hartinger, James D. Crowley
Summary: A strategy for generating heterotrimetallic double cavity cages and their interactions with different guest molecules were reported. The structures of the cages and their selective binding behavior were studied through various spectroscopic techniques. The results provide insights into the design and synthesis of multifunctional host-guest systems.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Inorganic & Nuclear
James A. Findlay, Daniel A. W. Ross, James D. Crowley
Summary: Three ferrocene-based rotary switches were developed using 2-pyridyl-1,2,3-triazole click chelates. The addition of compounds enabled the conformational switch of the rotors, but the weakness of the pytri chelates prevented the development of an electrochemically switchable system.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Lewis P. M. Green, Tasha R. Steel, Mie Riisom, Muhammad Hanif, Tilo Soehnel, Stephen M. F. Jamieson, L. James Wright, James D. Crowley, Christian G. Hartinger
Summary: Multimetallic complexes have been demonstrated to exhibit greater anticancer activity than monometallic counterparts, possibly due to altered modes of action. In this study, a series of heterodimetallic compounds were synthesized and characterized by various techniques. Proliferation assays in human cancer cell lines showed that most complexes were inactive.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Daniel A. W. Ross, James A. Findlay, Roan A. S. Vasdev, James D. Crowley
Summary: The study investigates the potential of utilizing new ligands pytri and tripy instead of commonly used polypyridyl ligands in copper(I)/(II) switching systems. The results show that the new ligands exhibit good binding ability in the copper(II) state but lower selectivity in the copper(I) state.
Article
Chemistry, Inorganic & Nuclear
Roan A. S. Vasdev, Dan Preston, Caitlin A. Casey-Stevens, Vicente Marti-Centelles, Paul J. Lusby, Anna L. Garden, James D. Crowley
Summary: This study attempts to generate reduced-symmetry [Pd-2(L)(4)](4+) cage architectures using supramolecular forces and solvophobic effects. The results show that the combination of dispersion forces and solvophobic effects does not provide control over the isomer distribution, while more control is obtained by exploiting hydrogen bonding interactions.
INORGANIC CHEMISTRY
(2022)
Review
Chemistry, Multidisciplinary
Aston C. Pearcy, James D. Crowley
Summary: This article outlines the use of metallosupramolecular structures to mimic the properties of biological enzymes and machines.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Inorganic & Nuclear
William D. J. Tremlett, Tilo Soehnel, James D. Crowley, L. James Wright, Christian G. Hartinger
Summary: Using ferrocene-based ligand systems, a series of heterobimetallic architectures were designed to release and bind guest molecules. The complexes were characterized using various techniques and the disassembly and reassembly process of metallosupramolecular structures were investigated using NMR spectroscopy. Guest binding studies revealed interactions with anionic guests and the release of guests was induced by Cl- ions.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Aston C. Pearcy, Lynn S. Lisboa, Dan Preston, Nick B. Page, Tristan Lawrence, L. James Wright, Christian G. Hartinger, James D. Crowley
Summary: A new sequential metalation strategy has been developed for the assembly of a more stable heterobimetallic [PdPtL4](4+) cage. By using a low-symmetry ditopic ligand (L) with imidazole and pyridine donor units, a [Pt(L)(4)](2+) open-cage complex was selectively formed and then reacted with Pd(ii) ions to assemble the cage C. Various spectroscopy and crystallography techniques confirmed the formation of the cage and its heterobimetallic structure. The cage C exhibited anionic guest molecule binding capability and demonstrated stimulus-responsive behavior.
Review
Chemistry, Multidisciplinary
Lana K. Moree, Logan A. V. Faulkner, James D. Crowley
Summary: In this tutorial review, the general methods for synthesizing heterometallic metallosupramolecular architectures (MSAs), specifically heterometallic cages, are examined. The intrinsic properties and potential applications of these cages as host-guest systems and reaction catalysts are discussed.
CHEMICAL SOCIETY REVIEWS
(2024)
Article
Chemistry, Inorganic & Nuclear
Lynn S. Lisboa, Mie Riisom, Henry J. Dunne, Dan Preston, Stephen M. F. Jamieson, L. James Wright, Christian G. Hartinger, James D. Crowley
Summary: A new [PdPtL4](4+) heterobimetallic cage containing hydrazone linkages was synthesized using the sub-component self-assembly approach. The cage showed stimulus-responsive behavior and was more stable against hydrolysis compared to a previously synthesized imine-containing cage. It interacted with cisplatin, while the smaller imine cage interacted with 5-fluorouracil and oxaliplatin.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Masoume Malmir, Majid M. Heravi, Zahra Yekke-Ghasemi, Masoud Mirzaei
Summary: In this study, a tri-component composite consisting of Fe3O4 nanoparticles, Keggin-type polyoxometalate, and graphene oxide was prepared and investigated as a catalyst for the oxidation of sulfides to sulfoxides. The catalyst showed excellent stability, high yields, and recyclability, making it a promising choice for organic-inorganic hybrid catalytic reactions conducted under mild conditions.
Article
Chemistry, Inorganic & Nuclear
Samuel D. Juarez-Escamilla, Sriloy Dey, Bruno Donnadieu, T. Keith Hollis
Summary: In this study, a bidentate Mo complex was synthesized using metalation and transmetalation methodology. The synthesis was optimized to achieve a high yield. The crystal structure of the bidentate complex was determined. Additionally, alternative forms of ligands were discovered in the reaction.
Article
Chemistry, Inorganic & Nuclear
Mohamed H. Abdel-Rhman, Ghada Samir, Mostafa A. Hussien, Nasser M. Hosny
Summary: This study investigated the dissolution performance of hydrazine carbonate solution on zirconium dibutyl phosphate (Zr-DBP), and found that hydrazine carbonate solution could promote the dissolution of Zr-DBP. The effects of dissolution temperature and hydrogen peroxide concentration on the dissolution efficiency were also explored, and the corrosion effect on stainless steel by hydrazine carbonate solution was studied.
Article
Chemistry, Inorganic & Nuclear
Qiaofang Fu, Fangyu Tan, Wu Ying
Summary: This study successfully prepared vermiculite/g-C3N4/TiO2 composites and found that under specific conditions, the composites exhibited excellent degradation effects, with a high degradation rate for methylene blue. Additionally, the composites were able to enhance surface area, reduce carrier loading rate, improve light energy utilization, and enhance durability.
Article
Chemistry, Inorganic & Nuclear
Annabelle G. W. Hodson, Robert T. Mason
Summary: Functionalised polystyrene resins have been found to be efficient catalysts in the synthesis of specific complexes, with the conversion rate controlled by the polymer structure. The addition of amines or amino acids can further yield substituted 13-butadienyl complexes, which have been analyzed by NMR.
Article
Chemistry, Inorganic & Nuclear
C. Kavitha, S. Anbarasan, P. Subramaniam
Summary: The sulfoxidation of PMAAs by the oxo(salen)chromium(V) complex in aqueous acetonitrile medium was studied. The rate of the reaction is influenced by the polarity of the medium and the substituents on PMAA, with electron donating substituents accelerating the reaction and electron withdrawing substituents retarding the reaction.
Article
Chemistry, Inorganic & Nuclear
Qiang-Qiang Liu, Mithun Kumar Ghosh, Shu-Lan Cai, Xiao-Hong Liu, Lu Lu, Mohd. Muddassir, Tanmay Kumar Ghorai, Jun Wang
Summary: Three newly developed coordination polymers (CPs) with semiconducting properties were synthesized using hydrothermal methods. These CPs exhibit superior photocatalytic activity and can degrade organic pollutants effectively.
Article
Chemistry, Inorganic & Nuclear
Mehrnaz Aliahmadi, Ali Nemati Kharat, Jan Janczak
Summary: This study proposes a method for synthesizing allyl alcohol using cost-effective and renewable bio-resource glycerol. By utilizing catalysts, alcohol as a solvent, and a reducing agent, allyl alcohol with an efficiency of 100% was obtained. The structures of the newly synthesized complexes were determined using X-ray single crystallography.
Article
Chemistry, Inorganic & Nuclear
Ji-Yan Gao, Nan Zhang, Dong-Sheng Huang, Xiang-Rong Liu, Zai-Wen Yang, Shun-Sheng Zhao
Summary: Two new transition metal complexes I and II were synthesized and characterized. The complexes exhibited strong thermal stabilities and showed effective binding to CT-DNA and BSA. Complex II exhibited stronger inhibition activity against P. aeruginosa than gentamicin sulfate. These complexes have potential applications in drug research.
Article
Chemistry, Inorganic & Nuclear
Rishabh Ujjval, Hilal Ahmad Khan, Chinnappan Sivasankar, Natesan Thirupathi
Summary: In this study, a rigid 2-aminobenzimidazole type guanidine and its platinum complexes were synthesized through a series of reactions and characterized by various physical and chemical methods. The reaction mechanism was also explained through DFT calculations.
Article
Chemistry, Inorganic & Nuclear
Marcelo Carpes Nunes, Thais Zaboenco, Vinicius Kemper Melara, Gabriel Barros Baptistella, Andre Luiz Barboza Formiga, Andersson Barison, Fabio Souza Nunes
Summary: A new luminescent molecular thermometer has been developed, which uses the spin-crossover equilibrium of a nickelcyclen derivative to measure temperature. The sensor shows high sensitivity and accuracy.
Article
Chemistry, Inorganic & Nuclear
Yuyu Shan, Zhenqin Zhao, Xia Zhang, Zhan Wu, Xiu-Ling Li
Summary: In this study, a new bridging ligand was synthesized through refluxing, and two mononuclear Cu(I) complexes and two trinuclear Cu(I)-Eu(III) complexes were obtained through self-assembly. The Cu(I) antenna chromophores successfully transferred energy to the Eu(III) centers, achieving sensitized Eu(III) luminescence.
Article
Chemistry, Inorganic & Nuclear
Gabriela Sanchez-Lecuona, Mayra C. Vazquez-Nunez, Bruno Donnadieu, Miguel A. Munoz-Hernandez, Virginia Montiel-Palma
Summary: The reaction of RuHCl(PPh3)3 with GaMe3 has been studied and the obtained complexes were analyzed in detail. The results indicate the formation of a Ru-Ga bond, suggesting the generation of an in situ formed ambiphilic phosphinogallyl ligand. This is of significance for understanding the interaction between metal-halogen bonds and metal-small molecule bonds.
Article
Chemistry, Inorganic & Nuclear
Sevil Sener, Nursel Acar, Fatih Dumludag
Summary: The synthesis, characterization, spectroscopic and bonding features of a new Co (II) phthalocyanine compound containing two thiocarbohydrazone groups were explained. The compound showed semiconductor properties and potential as a temperature sensor.
Article
Chemistry, Inorganic & Nuclear
Ledja B. O. Davi, Aryanna S. P. N. Costa, Mariana S. Silva, Adriana S. Ribeiro, Cintya D. A. E. S. Barbosa, Julio C. S. Da Silva, Dimas J. P. Lima, Daniela S. Anunciacao
Summary: In this study, a dansyl derivative sensor called o-PDDS was prepared and used for the detection of Al3+ ions in water. The o-PDDS sensor exhibited high sensitivity and linear response towards Al3+ ions. Experimental and computational studies confirmed a 1:1 stoichiometry ratio between o-PDDS and Al3+ ions. Real sample analysis demonstrated the selectivity and detection performance of the sensor, indicating its potential for field use.
