Review
Biochemistry & Molecular Biology
Chisato Kataoka, Shosaku Kashiwada
Summary: Exposure of aquatic organisms to immunotoxic pollutants may lead to changes in the immune system and health issues, even posing a threat to populations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Cell Biology
Mehdi Doumane, Marie-Cecile Caillaud, Yvon Jaillais
Summary: Phosphoinositides play critical roles in various biological processes and manipulating their levels accurately is crucial for understanding their functions. This review discusses different methods to manipulate phosphoinositide levels and highlights recent approaches in multicellular organisms.
TRENDS IN CELL BIOLOGY
(2022)
Review
Behavioral Sciences
Judit Cabana-Dominguez, Ester Anton-Galindo, Noelia Fernandez-Castillo, Euginia L. Singgih, Aet O'Leary, William Hg Norton, Tatyana Strekalova, Annette Schenck, Andreas Reif, Klaus-Peter Lesch, David Slattery, Bru Cormand
Summary: Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder with genetic and environmental risk factors. Co-occurrence of ADHD with other psychiatric disorders is well-established. Animal models have been used to study the molecular mechanisms of ADHD and its comorbidities, focusing on genetics and epigenetics. This review provides an overview of functional studies performed in rodents, zebrafish, and fruit fly, and highlights insights into the biology of ADHD. Behavioral tests for studying ADHD-related phenotypes and comorbid traits in these models are also described.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Review
Oncology
Lara Gibellini, Rebecca Borella, Elena Santacroce, Eugenia Serattini, Federica Boraldi, Daniela Quaglino, Beatrice Aramini, Sara De Biasi, Andrea Cossarizza
Summary: This review discusses the emerging concepts in the field of neutrophils in cancer, summarizing recent findings that highlight the role of both circulating neutrophils and tumor-associated neutrophils in tumor prognosis and resistance to immune checkpoint inhibitors. Neutrophils are the most abundant myeloid cells in the blood and significant components of the tumor microenvironment. However, their functional importance has been overlooked in the past due to the perception of them as a mono-dimensional population of terminally differentiated, short-lived cells. The use of cutting-edge single-cell technologies has revealed the phenotypic and functional heterogeneity of neutrophils, leading to a new understanding of their significance in cancer.
Review
Biochemistry & Molecular Biology
Changwon Yang, Whasun Lim, Gwonhwa Song
Summary: Excessively used pesticides in agricultural areas contaminate aquatic environments, affecting the reproduction and population stability of freshwater organisms, posing a threat to human health.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2021)
Article
Cell Biology
Douglas L. Rothman, Peter B. Moore, Robert G. Shulman
Summary: Since the discovery of the lac operon & SIM by Jacob and Monod in 1960, genetic explanations have dominated the understanding of metabolic adaptations. However, the roles of metabolism in adaptation have been largely overlooked. This article argues that metabolic adaptations, including changes in gene expression, depend heavily on the metabolic state of the organism prior to environmental changes, and the flexibility of that state. Using examples of E. coli adaptation to lactose growth and the Crabtree effect in yeast, the authors reevaluate these adaptations based on metabolic control analysis and emphasize the importance of understanding the metabolic properties of organisms prior to environmental changes.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Mariusz Sieminski, Karolina Szaruta-Raflesz, Jacek Szypenbejl, Klaudia Krzyzaniak
Summary: Sepsis-associated encephalopathy (SAE) is a brain injury caused by a dysregulated host response to infection, which can lead to various clinical symptoms and chronic cognitive dysfunction. Melatonin, with its anti-inflammatory and antioxidant properties, is considered a potential therapeutic factor in SAE, as it may exert a neuroprotective effect.
Review
Biochemistry & Molecular Biology
Chiara Lauritano, Eleonora Montuori, Gabriele De Falco, Sabrina Carrella
Summary: Marine organisms are valuable sources of bioactive molecules in various industries. In silico approaches, utilizing large-scale data analysis, offer a time- and cost-effective method for predicting the bioactivity of marine molecules.
Article
Cell Biology
Catherine B. Anders, Tyler M. W. Lawton, Hannah L. Smith, Jamie Garret, Margaret M. Doucette, Mary Cloud B. Ammons
Summary: The study utilized an ex vivo model to generate 6 distinct functional phenotypes of macrophages, profiling them based on cell surface markers, secreted proteins, gene expression, and metabolites. The research identified unique metabolic profiles for each phenotype, grouping them into inflammatory and wound resolution categories, with key differences observed in metabolic pathways. Ultimately, the integration of metabolomics provided a comprehensive understanding of macrophage diversity and functional plasticity.
JOURNAL OF LEUKOCYTE BIOLOGY
(2022)
Article
Chemistry, Applied
Chang Shu, Jiankang Cao, Weibo Jiang
Summary: Energy metabolism plays a crucial role in the response of fruit to vibration stress. Providing sufficient energy can alleviate adverse effects and maintain fruit quality.
Article
Clinical Neurology
Megan G. Janeway, Xiang Zhao, Max Rosenthaler, Yi Zuo, Kumar Balasubramaniyan, Michael Poulson, Miriam Neufeld, Jeffrey J. Siracuse, Courtney E. Takahashi, Lisa Allee, Tracey Dechert, Peter A. Burke, Feng Li, Bindu Kalesan
Summary: This study identified three distinct diagnostic phenotypes in hospitalizations due to self-inflicted firearm injuries. DP1 included common diagnoses such as major depressive disorders, hypertension, and acute post hemorrhagic anemia. DP2 covered children and peripartum women, while DP3 had a high prevalence of depression similar to DP1. Further research is needed to explore how these DPs can be utilized for tailored clinical care and prevention efforts.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Immunology
Cheng Len Sy, Pao-Yu Chen, Chun-Wen Cheng, Ling-Ju Huang, Ching-Hsun Wang, Tu-Hsuan Chang, Yi-Chin Chang, Chia-Jung Chang, Ing-Moi Hii, Yu-Lung Hsu, Ya-Li Hu, Pi-Lien Hung, Chen-Yen Kuo, Pei-Chin Lin, Po-Yen Liu, Ching-Lung Lo, Shih-Hao Lo, Pei-Ju Ting, Chien-Fang Tseng, Hsiao-Wei Wang, Ching-Hsiang Yang, Susan Shin-Jung Lee, Yao-Shen Chen, Yung-Ching Liu, Fu-Der Wang
Summary: Antimicrobial drug resistance is a major threat to global health, leading to difficulties in treating common infections and increased medical costs. The Taiwan Society of Microbiology has published the Guidelines Recommendations for Evidence-based Antimicrobial agents use in Taiwan (GREAT) to assist clinicians in managing infections caused by multidrug-resistant organisms (MDRO). The guidelines take into account local epidemiology and include antimicrobial agents that may not yet be available in Taiwan.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2022)
Article
Toxicology
Haiyi Yu, Liting Xu, Tenglong Cui, Yu Wang, Baoqiang Wang, Ze Zhang, Ruijun Su, Jingxu Zhang, Rong Zhang, Yanhong Wei, Daochuan Li, Xiaoting Jin, Wen Chen, Yuxin Zheng
Summary: Fine particulate matter (PM) is a major environmental factor contributing to the development of atherosclerosis. This study found that exposure to PM promoted the formation of foam cells, a crucial pathological process in atherosclerosis. Additionally, magnetite nanoparticles were identified as a key toxic component of PM in facilitating foam cell formation.
TOXICOLOGICAL SCIENCES
(2022)
Review
Nutrition & Dietetics
Jinliang Hou, Jianguo Xiang, Deliang Li, Xinhua Liu, Wangcheng Pan
Summary: There is an important relationship between gut microbes and host metabolic phenotypes, as they participate in host metabolism, physiology, and immunity through mechanisms such as metabolite differences and gene expression. Understanding this relationship can lead to new ways to prevent and treat metabolic diseases.
FRONTIERS IN NUTRITION
(2022)
Review
Food Science & Technology
B. Mahalakshmi, Chih-Yang Huang, Shin-Da Lee, Nancy Maurya, Rudolf Kiefer, V. Bharath Kumar
Summary: Danshen, a traditional Chinese medicine, has been shown to have therapeutic effects in various diseases, with protective, anti-inflammatory, antioxidative, or antiplatelet properties. Research has demonstrated its potential in medical applications for conditions like diabetes, neurological disorders, and cancer, providing a scientific basis for its traditional use in these diseases.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Plant Sciences
Santiago Michavila, Antonio Encina, Carlos Frey, Rafael Alvarez
Summary: This study described the anatomical structure of Saxifraga paniculata leaves, with a focus on structures related to CaCO3 release, such as stomata distribution, trichome morphology, and venation patterns.
Article
Plant Sciences
Gracielle Pereira Pimenta Braganca, Bruno Garcia Ferreira, Rosy Mary dos Santos Isaias
Summary: The study tested three gall morphotypes induced by Cecidomyiidae on leaflets of Inga ingoides and found that different gall types exhibit differences in cytological and metabolic traits, as well as in the accumulation of primary metabolites. The presence of fungi influences the system but does not define exclusive features for specific gall types, with distinct cytological mechanisms identified for each gall type in terms of food resources availability.
Article
Ecology
Elaine C. Costa, Vitor C. Martini, Aline Souza-Silva, Jose P. Lemos-Filho, Denis C. Oliveira, Rosy M. S. Isaias
Summary: The success of galling insects in a shared microhabitat depends on the synchrony and asynchrony of their life cycles, as well as the availability of water potential and resources in the environment.
Article
Plant Sciences
Bruno G. Ferreira, Gilson R. P. Moreira, Rene G. S. Carneiro, Rosy M. S. Isaias
Summary: This study provides a detailed description of the morphogenetic changes induced by E. minutanus in the lateral buds of S. engleri. The stages of gall development are associated with the development of specific instars of E. minutanus.
AMERICAN JOURNAL OF BOTANY
(2022)
Article
Plant Sciences
Larissa Quirino da Silva, Cristina Moll Huther, Natalia Fernandes Rodrigues, Julia Ramos de Oliveira, Daniela Marques Correia, Bruno Garcia Ferreira, Vitor Francisco Ferreira, Mariana de Oliveira Pereira, Bruna de Carvalho Assuncao, Gabriela Martins Correa, Filipe Rodrigues Valeriano, Leticia Ponticel Nobrega, Daiane Cecchin, Thelma Machado, Silvio Roberto de Lucena Tavares, Carlos Pereira
Summary: This study assessed the morphophysiological responses of comfrey to short-term severe water restriction and found that water deficit affected the growth and metabolism of comfrey plants. However, adjustments in photosynthetic apparatus and increased dry mass productivity indicated a possible adjustment to severe drought.
Article
Plant Sciences
L. P. Nobrega, B. De Sa-Haiad, B. G. Ferreira
Summary: Intralaminar galls of Meunieriella are the result of ground tissue proliferation in leaves of Avicennia schaueriana, a typical halophytic mangrove. Preferred sites of gall induction were found to be the midribs and secondary veins (SV) at the basal leaf portion, where the galls were largest. The vascular system in galls and adjacent regions was altered to favor water supply in galls, thus increasing their growth.
Article
Plant Sciences
Rayssa Rosa Marquesine de Castro, Pedro Ernandez Ferreira Barbosa, Leonardo Guimaraes Sant'Anna, Caio Marcello da Silva Pereira, Bruno Garcia Ferreira
Summary: Gall-inducing insects stimulate host plants to form distinct structures, like the fusiform galls induced by Clinodiplosis profusa. Infestation rates of these galls are similar in sun and shade plants, but there are differences in cell size and epidermal features between sun and shade galls. In conclusion, gall formation is influenced by galling stimuli, while some developmental processes are influenced by light exposure.
Article
Plant Sciences
Roberta Mendes Isaac Ferreira Vilela, Vinicius Coelho Kuster, Thiago Alves Magalhaes, Vitor Campana Martini, Renato Marques Oliveira, Denis Coelho de Oliveira
Summary: This study evaluated the impact of root-knot nematode infection on the agronomic traits, histology, and cell wall components of parsley, with a focus on giant cell formation. The results showed that Meloidogyne incognita infection affected the development of parsley, reducing root weight, shoot weight, and height. Giant cell formation caused disorganization of the vascular system and had a negative effect on the development of the crop.
Article
Plant Sciences
Vanessa Lino, Atiles Reis, Yve Canaveze, Murilo Sartarelli Farah, Lana da Silva Sylvestre, Bruno Garcia Ferreira
Summary: Ferns have two types of trichomes, hairs and scales, on their stems and leaves. The morphology and histochemistry of glandular scales in Asplenium spp. were investigated using different species under microscopes. The glandular scales had swollen cells with variable number stalks and secreted mucilage, pectins, phenolics, essential oils, and oleoresins. These secretions may provide resistance to desiccation, protection against herbivores and pathogens. Species and habits of the ferns influenced the secretory composition of the scales.
Article
Plant Sciences
Uiara Costa Rezende, Pedro Henrique Pereira Goncalves, Vinicius Coelho Kuster, Rene Goncalves da Silva Carneiro, Denis Coelho de Oliveira
Summary: Galls are a manifestation of the reprogramming of plant cell growth induced by organisms. The morphology and histological features of galls depend on the galling insect taxa and the targeted plant organ. The study found that the galls induced by Palaeomystella oligophaga on Macairea radula are stem-like galls with stem-branch vascular connections, which provide shelters for various arthropods.
Article
Multidisciplinary Sciences
Leticia Ponticel Nobrega, Barbara de Sa Haiad, Bruno Garcia Ferreira
Summary: Leaf-galling Eriophyidae can cause simple or complex alterations in the host plants' organs. Hairy galls on Avicennia schaueriana were found to occur mostly at the apical portion of the leaves and leaf margins. The gall anatomy showed influence on epidermal features and complex changes in abaxial epidermal cells close to feeding sites of the inducer. The gall size was mainly influenced by the number of inducers per gall, rather than the position in the leaves.
Article
Entomology
Uiara Costa Rezende, Joao Custodio Fernandes Cardoso, Pedro Henrique Pereira Goncalves, Denis Coelho de Oliveira
Summary: The study investigated the impact of the micromoth Palaeomystella oligophaga on the formation of galls on Macairea radula and found that it exhibits a bivoltine life cycle influenced by stochastic events like fire.
INTERNATIONAL JOURNAL OF TROPICAL INSECT SCIENCE
(2023)
Article
Biology
Vinicius Coelho Kuster, Joao Custodio Fernandes Cardoso, Ana Silvia Franco Pinheiro Moreira, Rosy Mary dos Santos Isaias, Denis Coelho de Oliveira
Summary: This study evaluated oxidative stress, photochemical parameters, and pigment contents in four leaf galls caused by different galling insects on Aspidosperma spp. It was found that different galling systems have underlying mechanisms that impact gall tissues.
Article
Microbiology
Joao C. M. Dornelas, Marliete C. Costa, Paulo H. F. Carmo, Vivian M. Paixao, Vanessa S. D. Carvalho, Leilane C. Barreto, Queila S. Garcia, Gracielle P. P. Braganca, Rosy M. S. Isaias, Julio C. M. Brito, Maria A. Resende-Stoianoff, Daniel A. Santos
Summary: This study developed a plant model to investigate the interaction between Cryptococcus gattii and plants. The results showed that C. gattii can grow in plants without causing pathological effects. N. benthamiana exhibited higher proliferation of C. gattii, accompanied by an increase in hydrogen peroxide content, antioxidant system activity, and indoleacetic acid production. Colonies of C. gattii recovered from N. benthamiana displayed altered composition and morphology, as well as increased resistance to antifungal drugs. These findings suggest that plants may serve as a potential reservoir and transmission route for C. gattii.
FEMS MICROBIOLOGY ECOLOGY
(2022)