Lipopolysaccharide potentiates platelet responses via toll-like receptor 4-stimulated Akt-Erk-PLA2 signalling

Lipopolysaccharide as trigger of platelet aggregation via eicosanoid over-production

(2017) Simona Bartimoccia et al.   THROMBOSIS AND HAEMOSTASIS

Potential diagnostic markers for disseminated intravascular coagulation of sepsis

(2016) Toshiaki Iba et al.   BLOOD REVIEWS

Phosphatidylinositol-3,4,5-trisphosphate stimulates Ca2+ elevation and Akt phosphorylation to constitute a major mechanism of thromboxane A2 formation in human platelets

(2015) Nick Kassouf et al.   CELLULAR SIGNALLING

Unfractionated heparin attenuates LPS-induced IL-8 secretion via PI3K/Akt/NF-κB signaling pathway in human endothelial cells

(2015) Xu Li et al.   IMMUNOBIOLOGY

The inflammatory role of platelets via their TLRs and Siglec receptors

(2015) Fabrice Cognasse   Frontiers in Immunology

Secretory phospholipase A2 enzymes as pharmacological targets for treatment of disease

(2014) Nhat D. Quach et al.   BIOCHEMICAL PHARMACOLOGY

Toll-Like Receptor Signaling Pathways

(2014) Takumi Kawasaki et al.   Frontiers in Immunology

Role for Platelet Glycoprotein Ib-IX and Effects of its Inhibition in Endotoxemia-Induced Thrombosis, Thrombocytopenia, and Mortality

(2013) Hong Yin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of platelet responses triggered by Toll-like receptor 2 and 4 ligands is another non-genomic role of nuclear factor-kappaB

(2013) Leonardo Rivadeneyra et al.   THROMBOSIS RESEARCH

The PI3K/Akt pathway is required for LPS activation of microglial cells

(2012) Concetta Saponaro et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Regulation of Inflammatory Cytokines in Lipopolysaccharide-Stimulated RAW 264.7 Murine Macrophage by 7-O-Methyl-naringenin

(2012) Lanan Wassy Soromou et al.   MOLECULES

Lipopolysaccharide Signaling without a Nucleus: Kinase Cascades Stimulate Platelet Shedding of Proinflammatory IL-1 -Rich Microparticles

(2011) G. T. Brown et al.   JOURNAL OF IMMUNOLOGY

Reactive oxygen and nitrogen species modulate the ex-vivo effects of LPS on platelet adhesion to fibrinogen

(2011) André Luis Casarin et al.   LIFE SCIENCES

Lipopolysaccharide treatment reduces rat platelet aggregation independent of intracellular reactive-oxygen species generation

(2011) M. Elisa Lopes-Pires et al.   PLATELETS

Signaling During Platelet Adhesion and Activation

(2010) Zhenyu Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Mechanisms underlying the inhibitory effects of lipopolysaccharide on human platelet adhesion

(2010) Rafael P. Morganti et al.   PLATELETS

Platelets as immune mediators: Their role in host defense responses and sepsis

(2010) Zhenyu Li et al.   THROMBOSIS RESEARCH

Akt signaling in platelets and thrombosis

(2010) Donna S Woulfe   Expert Review of Hematology

Stretch-induced ERK2 phosphorylation requires PLA2 activity in skeletal myotubes

(2009) Thomas J. Burkholder   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Toll-like receptor signaling in cell proliferation and survival

(2009) Xinyan Li et al.   CYTOKINE

Lipopolysaccharide Stimulates Platelet Secretion and Potentiates Platelet Aggregation via TLR4/MyD88 and the cGMP-Dependent Protein Kinase Pathway

(2009) G. Zhang et al.   JOURNAL OF IMMUNOLOGY

A Functional Proteomic Method for the Enrichment of Peripheral Membrane Proteins Reveals the Collagen Binding Protein Hsp47 Is Exposed on the Surface of Activated Human Platelets

(2009) William J. Kaiser et al.   JOURNAL OF PROTEOME RESEARCH

Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway

(2008) P. Flevaris et al.   BLOOD

Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human platelets

(2008) Fabrice Cognasse et al.   BRITISH JOURNAL OF HAEMATOLOGY

The platelet release reaction: just when you thought platelet secretion was simple

(2008) Qiansheng Ren et al.   CURRENT OPINION IN HEMATOLOGY

Spatially distinct production of reactive oxygen species regulates platelet activation

(2008) Nadia Bakdash et al.   FREE RADICAL BIOLOGY AND MEDICINE