Article
Oncology
Kelly J. Yu, Wan-Lun Hsu, Chun-Ju Chiang, Tseng-Cheng Chen, Zhiwei Liu, Pei-Jen Lou, Scott Diehl, Alisa M. Goldstein, Chien-Jen Chen, Cheng-Ping Wang, Allan Hildesheim
Summary: This study reassessed familial aggregation of cancer in high-risk Taiwanese multiplex families with NPC cases and found evidence of NPC coaggregation within families, but not a broader familial syndrome involving NPC and other tumors. The study also observed elevated rates of secondary cancers among NPC cases, mostly head and neck and hematopoietic cancers, suggesting radiation treatment effects on subsequent cancer risk.
Article
Microbiology
Rozenn Souillard, Jeanne Laurentie, Isabelle Kempf, Virginie Le Caer, Sophie Le Bouquin, Pascale Serror, Virginie Allain
Summary: This study assesses the occurrence of enterococci in poultry in France based on veterinary laboratory data. The results show the emergence of enterococcal diseases in poultry over the past 15 years, particularly in broilers, and emphasize the importance of maintaining a surveillance system.
VETERINARY MICROBIOLOGY
(2022)
Article
Critical Care Medicine
Carolina Lorencio Cardenas, Juan Carlos Yebenes, Emili Vela, Montserrat Cleries, Josep Ma Sirvent, Cristina Fuster-Bertolin, Clara Reina, Alejandro Rodriguez, Juan Carlos Ruiz-Rodriguez, Josep Trenado, Elisabeth Esteban Torne
Summary: The incidence of sepsis has been increasing in recent years, but hospital mortality has significantly decreased. In septic patients, all organ failures, except liver failure, have shown a statistically significant reduction in associated mortality.
Article
Infectious Diseases
Fiona Steiner, Stefan Schmutz, Rainer Gosert, Jon B. Huder, Patrick M. Redli, Riccarda Capaul, Hans H. Hirsch, Jurg Boni, Andrea Zbinden
Summary: The study compared the performance of ePlex respiratory pathogen panel (RPP) and FTD21 multiplex RT-PCR assay, showing differences in sensitivity and specificity. The ePlex RPP is valuable for rapid detection of respiratory viruses, except for the coronavirus family and samples with low pathogen load.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
(2021)
Article
Infectious Diseases
Suvi Mattila, Minna Honkila, Niko Paalanne, Vesa Maki-Koivisto, Kimmo Halt, Tuomas Jartti, Olli Ruuskanen, Matti Waris, Tytti Pokka, Terhi Tapiainen
Summary: A cohort study of 800 children at Oulu University Hospital in Finland found no association between cycle threshold values of respiratory viruses in point-of-care multiplex polymerase chain reaction testing and hospitalization, respiratory support, or need for intensive care.
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY
(2023)
Article
Immunology
Yannis Lassoued, Zein Assad, Naim Ouldali, Marion Caseris, Patricia Mariani, Andre Birgy, Stephane Bonacorsi, Philippe Bidet, Albert Faye
Summary: Since October 2022, there has been an increase in invasive Group A streptococcal (iGAS) infections, which coincided with a respiratory virus outbreak. Physicians need to be aware of the heightened risk of pediatric iGAS infections.
OPEN FORUM INFECTIOUS DISEASES
(2023)
Article
Environmental Sciences
Camille Inquimbert, Celine Clement, Antoine Couatarmanach, Paul Tramini, Denis Bourgeois, Florence Carrouel
Summary: The study found that adolescents undergoing orthodontic treatment had better knowledge of oral health compared to those without treatment, but both groups had insufficient knowledge. It is necessary to implement health education programs for adolescents to improve their knowledge of oral health.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Pediatrics
M. Rousseau, I. Asselin, R. Morello, X. Lecoutour, J. Brouard, R. Fauvet, A. -C. Pizzoferrato
Summary: This study aimed to determine the prevalence and vulnerability factors related to active cybersexuality among teenagers aged between 15 and 17 years in western Normandy. The results revealed that 66% of teenagers engaged in cybersex, with sexting being the most common practice. Factors such as gender, self-esteem, drug use, number of friends on social networks, and daily viewing of pornography were strongly associated with cybersexuality. Highlighting this theme during sexual education classes can help prevent potential risks.
ARCHIVES DE PEDIATRIE
(2023)
Article
Ophthalmology
Midiaou M. Bah, Fatoumata Sakho, Andre Goepogui, Luc C. Nieba, Abdourahim Cisse, Paul Courtright, Anna J. Harte, Clara Burgert-Brucker, Cristina Jimenez, Pierre L. Lama, Michel Sagno, Ana Bakhtiari, Sarah Boyd, Anthony W. Solomon, Michaela Kelly, Fiona James, Moise S. D. Tenkiano, Emma M. Harding-Esch, Boubacar M. Dicko
Summary: This study aims to assess the progress of trachoma elimination in Guinea. The study found that the inflammatory trachoma prevalence in Guinea was below the WHO elimination threshold, but the trachomatous trichiasis (TT) prevalence was above it. These survey results provide critical data for evaluating Guinea's achievement of trachoma elimination targets.
OPHTHALMIC EPIDEMIOLOGY
(2023)
Article
Substance Abuse
Andre Wamba, Jeremie Pourchez, Julien Masson, Christine Denis-Vatant, Lara Leclerc, Mabrouc Nekaa
Summary: This study investigated the vaping and smoking habits of French adolescents aged 15-16 years. The results showed that less than half of adolescents had experimented with e-cigarettes and smoked tobacco, and most of them did not continue using. Therefore, the impact of vaping on smoking initiation was rather marginal.
TOBACCO PREVENTION & CESSATION
(2023)
Article
Medicine, General & Internal
Josue A. Melendez-Asipali, Ruben Espinoza, Rosa Rivadeneyra-Romero, Jose M. Vela-Ruiz, Jhony A. De la Cruz-Vargas
Summary: This study found that in Peruvian women between the ages of 15 and 49, there is a positive association between living in an urban area, being married, having a high educational level, and having the first sexual intercourse before the age of 17 with the use of contraceptive methods.
REVISTA DEL CUERPO MEDICO DEL HOSPITAL NACIONAL ALMANZOR AGUINAGA ASENJO
(2022)
Review
Pharmacology & Pharmacy
Laura Saint-Lary, Alpha Diallo, Laure-Amelie de Monteynard, Christelle Paul, Lucie Marchand, Roland Tubiana, Josiane Warszawski, Laurent Mandelbrot, Claire Rekacewicz, Ventzislava Petrov-Sanchez, Albert Faye, Jeanne Sibiude, Francois Dabis, Agnes Sommet, Valeriane Leroy
Summary: The study found that the use of protease inhibitor (PI) and non-nucleoside reverse transcriptase inhibitor (NNRTI) based regimens did not show significant association with adverse pregnancy outcomes, except for nucleoside reverse transcriptase inhibitor (NRTI) combinations. The number of integrase inhibitor (INI)-based combinations was too low to draw conclusions from.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Lorraine Poncet, Henri Panjo, Thomas Schmitz, Dominique Luton, Laurent Mandelbrot, Candice Estellat, Armelle Andro, Virginie Ringa, Elie Azria
Summary: Migrant women in France are at higher risk of inadequate GWG. Non-migrant women with foreign origins had increased risk of excessive GWG. Women born in Sub-Saharan Africa had increased risk of both inadequate and excessive GWG. Women with lower education and women who did not start pregnancy with a normal weight were less likely to gain adequately. Inadequate prenatal care was associated with inadequate GWG only among non-migrant women.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2022)
Article
Obstetrics & Gynecology
Maxime Eslier, Catherine Deneux-Tharaux, Priscille Sauvegrain, Thomas Schmitz, Dominique Luton, Laurent Mandelbrot, Candice Estellat, Elie Azria
Summary: Undocumented migrants from sub-Saharan Africa in Europe have the highest risk of severe maternal morbidity among migrant subgroups. They are more likely to experience social isolation, linguistic barriers, and poor housing conditions compared to other migrants and non-migrants. Their interaction with maternity care services appears to be sub-optimal.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Medicine, General & Internal
L. Mandelbrot
Summary: Bacterial, viral, and parasitic infections have an impact on pregnant women and their fetuses, but treatment and preventive measures using anti-infective drugs can reduce the transmission of infections. Treatment for certain diseases has been well established, but new approaches are needed for detecting and treating emerging infection routes and diseases. Research on the use of anti-infectives during pregnancy is gaining attention, and systematic studies on the placental transfer and drug surveillance are necessary. Active screening policies and vaccination are the most effective methods for preventing infections.
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE
(2022)
Article
Immunology
Catherine Dollfus, Jerome Le Chenadec, Laurent Mandelbrot, Roland Tubiana, Albert Faye, Maud Brossard, Pierre Frange, Stephane Blanche, Josiane Warszawski
Summary: In the ANRS French Perinatal Cohort, it was found that nevirapine (NVP) had a lower frequency of anemia grade >= 2 compared to zidovudine (AZT) in infants at low risk of HIV acquisition.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2022)
Article
Multidisciplinary Sciences
Charles Egloff, Camille Couffignal, Anne Gael Cordier, Philippe Deruelle, Jeanne Sibiude, Olivia Anselem, Alexandra Benachi, Dominique Luton, Laurent Mandelbrot, Christelle Vauloup-Fellous, Alexandre J. Vivanti, Olivier Picone
Summary: This study evaluated pregnant women's perceptions and acceptance of COVID-19 vaccination. The results showed that about one-third of pregnant women were willing to receive the vaccine, with the main reason for refusal being concerns about potential side effects on the fetus. Factors influencing acceptance included age, multiparity, discussion with healthcare providers, and acceptance of the influenza vaccine.
Article
Medicine, General & Internal
Donia Bouzid, Benoit Visseaux, Christian Kassasseya, Asma Daoud, Florent Femy, Christelle Hermand, Jennifer Truchot, Sebastien Beaune, Nicolas Javaud, Olivier Peyrony, Anthony Chauvin, Prabakar Vaittinada Ayar, Arthur Bourg, Bruno Riou, Stephane Marot, Ben Bloom, Marine Cachanado, Tabassome Simon, Yonathan Freund
Summary: This study compares baseline characteristics and in-hospital outcomes of patients with SARS-CoV-2 infection with the Delta variant versus the Omicron variant in the emergency department. The results show that patients infected with the Omicron variant were younger, had a lower rate of obesity, were more vaccinated, had a lower rate of dyspnea, and had a higher rate of discharge home from the ED. Compared with Delta, Omicron infection was independently associated with a lower risk for ICU admission, mechanical ventilation, and in-hospital mortality.
ANNALS OF INTERNAL MEDICINE
(2022)
Meeting Abstract
Obstetrics & Gynecology
M. Eslier, C. Deneux-Tharaux, P. Sauvegrain, T. Schmitz, D. Luton, L. Mandelbrot, C. Estellat, E. Azria
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2022)
Review
Genetics & Heredity
Marion David, Najeh Hcini, Laurent Mandelbrot, Jeanne Sibiude, Olivier Picone
Summary: The recent increase in congenital syphilis infection is causing fetal and neonatal abnormalities among women of childbearing age. This study aims to summarize these abnormalities, particularly the ones that can be diagnosed prenatally.
PRENATAL DIAGNOSIS
(2022)
Article
Public, Environmental & Occupational Health
Jeremie Mattern, Irene Letendre, Jeanne Sibiude, Cecile Penager, Asma Jnifen, Fatoumata Souare, Sophie Ayel, Thuy Nguyen, Laurent Mandelbrot
Summary: In an urban population in France, factors associated with a diagnosis of cervical cancer at advanced stages include lack of regular gynecological care, absence of Pap test screening, and high parity.
Review
Obstetrics & Gynecology
Karl Wehbe, Lucille Pencole, Martin Lhuaire, Jeanne Sibiude, Laurent Mandelbrot, Isabelle Villena, Olivier Picone
Summary: This systematic review aimed to assess the effectiveness of hygiene measures during pregnancy to prevent toxoplasmosis infection. The findings suggest that hygiene measures are effective primary prevention strategies in reducing toxoplasmosis and avoiding congenital toxoplasmosis and its consequences.
JOURNAL OF GYNECOLOGY OBSTETRICS AND HUMAN REPRODUCTION
(2022)
Review
Genetics & Heredity
Lucile Pencole, Jeanne Sibiude, A. S. Weingertner, Laurent Mandelbrot, Christelle Vauloup-Fellous, Olivier Picone
Summary: LCMV is a rare congenital infection that can result in high mortality and morbidity. This article reviews the various morphological abnormalities associated with congenital LCMV infection, including brain abnormalities such as chorioretinitis, hydrocephaly, microcephaly, ventriculomegaly, and periventricular calcifications. Other extracerebral abnormalities such as small for gestational age, ascites, cardiomegaly, and anemia were also observed. Antenatal ultrasound examination could detect major cerebral abnormalities in 70% of cases. Congenital LCMV infection is associated with a significant mortality rate and survivors often suffer from severe neurological sequelae.
PRENATAL DIAGNOSIS
(2022)
Article
Immunology
Jeanne Sibiude, Jerome Le Chenadec, Laurent Mandelbrot, Alexandre Hoctin, Catherine Dollfus, Albert Faye, Eida Bui, Emmanuelle Pannier, Jade Ghosn, Valerie Garrait, Veronique Avettand-Fenoel, Pierre Frange, Josiane Warszawski, Roland Tubiana
Summary: Antiretroviral therapy initiated before pregnancy and continued throughout pregnancy can significantly reduce perinatal transmission of HIV. Factors such as not breastfeeding, infant prophylaxis, and maternal viral suppression near delivery play important roles in preventing transmission.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Medicine, General & Internal
Gabriel Marcellier, Axelle Dupont, Agnes Bourgeois-Moine, Arnaud Le Tohic, Celine De Carne-Carnavalet, Olivier Poujade, Guillaume Girard, Amelie Benbara, Laurent Mandelbrot, Laurent Abramowitz
Summary: Postpartum anal incontinence is common. Follow-up is advised after a first delivery with perineal trauma to reduce the risk of anal incontinence. Endoanal sonography may be considered to evaluate the sphincter and discuss cesarean section for the second delivery. Risk factors for anal continence impairment after the second delivery were the presence of urinary incontinence and the combined use of instruments and episiotomy. Sphincter rupture diagnosed through endoanal sonography was not associated with continence impairment after the second delivery.
JOURNAL OF CLINICAL MEDICINE
(2023)
Meeting Abstract
Obstetrics & Gynecology
Camille Le Ray, Patrick Rozenberg, Gilles Kayem, Thierry Harvey, Laurent Mandelbrot, Muriel Doret, Olivier Parant, Florent Fuchs, Delphine Vardon, Elie Azria, Hanane Bouchghoul, Pierre-Francois Ceccaldi, Aurelien Seco, Charles Garabedian, Anne Chantry
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
