Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host

Plastid intramembrane proteolysis

(2015) Zach Adam   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Parasite-induced ER stress response in hepatocytes facilitates Plasmodium liver stage infection

(2015) P. Inacio et al.   EMBO REPORTS

In Vivo Function of PTEX88 in Malaria Parasite Sequestration and Virulence

(2015) Joachim M. Matz et al.   EUKARYOTIC CELL

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Twenty years of theMEROPSdatabase of proteolytic enzymes, their substrates and inhibitors

(2015) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Ectopic Expression of a Neospora caninum Kazal Type Inhibitor Triggers Developmental Defects in Toxoplasma and Plasmodium

(2015) Zoi Tampaki et al.   PLoS One

Plasmodium falciparum signal peptide peptidase cleaves malaria heat shock protein 101 (HSP101). Implications for gametocytogenesis

(2014) Michael Baldwin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A comprehensive evaluation of rodent malaria parasite genomes and gene expression

(2014) Thomas D Otto et al.   BMC BIOLOGY

The Rip1 Protease of Mycobacterium tuberculosis Controls the SigD Regulon

(2014) J. S. Schneider et al.   JOURNAL OF BACTERIOLOGY

Endoplasmic Reticulum Stress Triggers Gametocytogenesis in the Malaria Parasite

(2014) Shweta Chaubey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Site-2 protease responds to oxidative stress and regulates oxidative injury in mammalian cells

(2014) Yong Gu et al.   Scientific Reports

The roles of intramembrane proteases in protozoan parasites

(2013) L. David Sibley   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Function of site-2 proteases in bacteria and bacterial pathogens

(2013) Jessica S. Schneider et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Loss-of-function analyses defines vital and redundant functions of thePlasmodiumrhomboid protease family

(2013) Jing-wen Lin et al.   MOLECULAR MICROBIOLOGY

Identification of a Novel and Unique Transcription Factor in the Intraerythrocytic Stage of Plasmodium falciparum

(2013) Kanako Komaki-Yasuda et al.   PLoS One

The Plasmodium falciparum Schizont Phosphoproteome Reveals Extensive Phosphatidylinositol and cAMP-Protein Kinase A Signaling

(2012) Edwin Lasonder et al.   JOURNAL OF PROTEOME RESEARCH

Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design

(2012) M. B. Harbut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Malaria Parasite Signal Peptide Peptidase is an ER-Resident Protease Required for Growth but not for Invasion

(2012) Danushka S. Marapana et al.   TRAFFIC

Shedding of TRAP by a Rhomboid Protease from the Malaria Sporozoite Surface Is Essential for Gliding Motility and Sporozoite Infectivity

(2012) Ijeoma Ejigiri et al.   PLoS Pathogens

Proteases as regulators of pathogenesis: Examples from the Apicomplexa

(2011) Hao Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The Phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii Reveal Unusual Adaptations Within and Beyond the Parasites' Boundaries

(2011) Moritz Treeck et al.   Cell Host & Microbe

Use of Recombinase-BasedIn VivoExpression Technology To Characterize Enterococcus faecalis Gene Expression during Infection IdentifiesIn Vivo-Expressed Antisense RNAs and Implicates the Protease Eep in Pathogenesis

(2011) Kristi L. Frank et al.   INFECTION AND IMMUNITY

A scalable pipeline for highly effective genetic modification of a malaria parasite

(2011) Claudia Pfander et al.   NATURE METHODS

Proteases of Plasmodium falciparum as Potential Drug Targets and Inhibitors Thereof

(2010) Christof Wegscheid-Gerlach et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

M. tuberculosis intramembrane protease Rip1 controls transcription through three anti-sigma factor substrates

(2010) Joseph G. Sklar et al.   MOLECULAR MICROBIOLOGY

A novel clan of zinc metallopeptidases with possible intramembrane cleavage properties

(2010) Alan P. Lewis et al.   PROTEIN SCIENCE

Natural Immunization Against Malaria: Causal Prophylaxis with Antibiotics

(2010) J. Friesen et al.   Science Translational Medicine

Activation of Sterol Regulatory Element-binding Protein by the Caspase Drice inDrosophilaLarvae

(2009) Bilal Amarneh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryptococcus neoformansSite-2 protease is required for virulence and survival in the presence of azole drugs

(2009) Clara M. Bien et al.   MOLECULAR MICROBIOLOGY

Linear plasmid vector for cloning of repetitive or unstable sequences in Escherichia coli

(2009) Ronald Godiska et al.   NUCLEIC ACIDS RESEARCH

PbCap380, a novel oocyst capsule protein, is essential for malaria parasite survival in the mosquito

(2008) Prakash Srinivasan et al.   CELLULAR MICROBIOLOGY

Malarial proteases and host cell egress: an ‘emerging’ cascade

(2008) Michael J. Blackman   CELLULAR MICROBIOLOGY

A Sporozoite Asparagine-Rich Protein Controls Initiation of Plasmodium Liver Stage Development

(2008) Olivier Silvie et al.   PLoS Pathogens