Tyrosine Binding Protein Sites Regulate the Intracellular Trafficking and Processing of Amyloid Precursor Protein through a Novel Lysosome-Directed Pathway

New Insights to Clathrin and Adaptor Protein 2 for the Design and Development of Therapeutic Strategies

(2015) Ebbe Poulsen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes

(2015) Weihao Tang et al.   Molecular Brain

SAP97-mediated ADAM10 trafficking from Golgi outposts depends on PKC phosphorylation

(2014) C Saraceno et al.   Cell Death & Disease

The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid

(2014) Joshua HK Tam et al.   Molecular Brain

γ-Secretase and Presenilin Mediate Cleavage and Phosphorylation of Vascular Endothelial Growth Factor Receptor-1

(2011) Jun Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PKC   Activation Prevents Synaptic Loss, A  Elevation, and Cognitive Deficits in Alzheimer's Disease Transgenic Mice

(2011) J. Hongpaisan et al.   JOURNAL OF NEUROSCIENCE

TACE/ADAM-17 Phosphorylation by PKC-Epsilon Mediates Premalignant Changes in Tobacco Smoke-Exposed Lung Cells

(2011) Hassan Lemjabbar-Alaoui et al.   PLoS One

A proximity ligation assay using transiently transfected, epitope-tagged proteins: application for in situ detection of dimerized receptor tyrosine kinases

(2010) Aaron Gajadhar et al.   BIOTECHNIQUES

Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex

(2010) Patricia V. Burgos et al.   DEVELOPMENTAL CELL

Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated

(2010) Sandra I Vieira et al.   Molecular Neurodegeneration

Rapid and Direct Transport of Cell Surface APP to the Lysosome defines a novel selective pathway

(2010) Angela Lorenzen et al.   Molecular Brain

Reduction of β-Amyloid Levels by Novel Protein Kinase Cϵ Activators

(2009) Thomas J. Nelson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S655 phosphorylation enhances APP secretory traffic

(2009) Sandra Isabel Vieira et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Retromer

(2008) Juan S Bonifacino et al.   CURRENT OPINION IN CELL BIOLOGY

Amyloid Precursor Protein Trafficking, Processing, and Function

(2008) Gopal Thinakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons

(2008) A. Schneider et al.   JOURNAL OF NEUROSCIENCE

A role for VEGF as a negative regulator of pericyte function and vessel maturation

(2008) Joshua I. Greenberg et al.   NATURE

Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo

(2008) John R. Cirrito et al.   NEURON

Mutant Presenilin 1 Increases the Levels of Alzheimer Amyloid β-Peptide Aβ42 in Late Compartments of the Constitutive Secretory Pathway

(2003) Suzana S. Petanceska et al.   JOURNAL OF NEUROCHEMISTRY