Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo
出版年份 2016 全文链接
标题
Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo
作者
关键词
Eyes, Retina, Photoreceptors, Mouse models, High performance liquid chromatography, Retinal degeneration, Macular degeneration, Isomers
出版物
PLoS One
Volume 11, Issue 12, Pages e0167793
出版商
Public Library of Science (PLoS)
发表日期
2016-12-20
DOI
10.1371/journal.pone.0167793
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration
- (2016) Deborah A. Ferrington et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease
- (2016) Paul S. Bernstein et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Prolonged prevention of retinal degeneration with retinylamine loaded nanoparticles
- (2015) Anthony Puntel et al. BIOMATERIALS
- Current therapeutic developments in atrophic age-related macular degeneration
- (2015) Jakub Hanus et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Cellular models and therapies for age-related macular degeneration
- (2015) D. L. Forest et al. Disease Models & Mechanisms
- Topical cyclodextrin reduces amyloid beta and inflammation improving retinal function in ageing mice
- (2015) Jaimie Hoh Kam et al. EXPERIMENTAL EYE RESEARCH
- Systemic administration of the apocarotenoid bixin protects skin against solar UV-induced damage through activation of NRF2
- (2015) Shasha Tao et al. FREE RADICAL BIOLOGY AND MEDICINE
- Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition
- (2015) Jilin Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular pharmacodynamics of emixustat in protection against retinal degeneration
- (2015) Jianye Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium
- (2015) Kimberly A. Toops et al. MOLECULAR BIOLOGY OF THE CELL
- Lutein suppresses inflammatory responses through Nrf2 activation and NF-κB inactivation in lipopolysaccharide-stimulated BV-2 microglia
- (2015) Wanqiang Wu et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration
- (2015) J Zhang et al. Cell Death & Disease
- PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage
- (2015) Megan Stiles et al. PLoS One
- Phase II enzyme induction by a carotenoid, lutein, in a PC12D neuronal cell line
- (2014) Seiji Miyake et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Emerging roles for nuclear receptors in the pathogenesis of age-related macular degeneration
- (2014) Goldis Malek et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Age-related Eye Disease Study 2
- (2014) Mary E. Aronow et al. CURRENT OPINION IN OPHTHALMOLOGY
- Morphological and physiological retinal degeneration induced by intravenous delivery of vitamin A dimers in rabbits
- (2014) Jackie Penn et al. Disease Models & Mechanisms
- All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis
- (2014) Osamu Sawada et al. EXPERIMENTAL EYE RESEARCH
- Carotenoids, inflammation, and oxidative stress—implications of cellular signaling pathways and relation to chronic disease prevention
- (2014) Anouk Kaulmann et al. NUTRITION RESEARCH
- Treatment of Dry Age-Related Macular Degeneration
- (2014) Giuseppe Querques et al. OPHTHALMIC RESEARCH
- Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium
- (2014) M. M. Nociari et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Zeaxanthin induces Nrf2-mediated phase II enzymes in protection of cell death
- (2014) X Zou et al. Cell Death & Disease
- Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD)
- (2013) Paulina Tokarz et al. BIOGERONTOLOGY
- Nutrient Supplementation with n3 Polyunsaturated Fatty Acids, Lutein, and Zeaxanthin Decrease A2E Accumulation and VEGF Expression in the Retinas of Ccl2/Cx3cr1-Deficient Mice on Crb1rd8 Background
- (2013) Hema L. Ramkumar et al. JOURNAL OF NUTRITION
- Review of nutrient actions on age-related macular degeneration
- (2013) Stefania Zampatti et al. NUTRITION RESEARCH
- A2E Induces IL-1ß Production in Retinal Pigment Epithelial Cells via the NLRP3 Inflammasome
- (2013) Owen A. Anderson et al. PLoS One
- Phototoxic Action Spectrum on a Retinal Pigment Epithelium Model of Age-Related Macular Degeneration Exposed to Sunlight Normalized Conditions
- (2013) Emilie Arnault et al. PLoS One
- Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation-related genes in retinal pigment epithelial cells
- (2012) Qingning Bian et al. FREE RADICAL BIOLOGY AND MEDICINE
- Bixin Activates PPARα and Improves Obesity-Induced Abnormalities of Carbohydrate and Lipid Metabolism in Mice
- (2012) Tsuyoshi Goto et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Annatto prevents retinal degeneration induced by endoplasmic reticulum stress in vitro and in vivo
- (2012) Kazuhiro Tsuruma et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Lipofuscin can be eliminated from the retinal pigment epithelium of monkeys
- (2012) Sylvie Julien et al. NEUROBIOLOGY OF AGING
- A Novel Source of Methylglyoxal and Glyoxal in Retina: Implications for Age-Related Macular Degeneration
- (2012) Kee Dong Yoon et al. PLoS One
- Lutein: More than just a filter for blue light
- (2012) Aize Kijlstra et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration
- (2011) Kati Kinnunen et al. ACTA OPHTHALMOLOGICA
- Research Resource: Nuclear Receptor Atlas of Human Retinal Pigment Epithelial Cells: Potential Relevance to Age-Related Macular Degeneration
- (2011) Mary A. Dwyer et al. MOLECULAR ENDOCRINOLOGY
- Primary amines protect against retinal degeneration in mouse models of retinopathies
- (2011) Akiko Maeda et al. Nature Chemical Biology
- Deuterium Enrichment of Vitamin A at the C20 Position Slows the Formation of Detrimental Vitamin A Dimers in Wild-type Rodents
- (2010) Yardana Kaufman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enzymatic Degradation of A2E, a Retinal Pigment Epithelial Lipofuscin Bisretinoid
- (2010) Yalin Wu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Targeting tissue oxidative damage by means of cell signaling modulators: The antioxidant concept revisited
- (2010) Gabriella Leonarduzzi et al. PHARMACOLOGY & THERAPEUTICS
- Mass spectrometry provides accurate and sensitive quantitation of A2E
- (2010) Danielle B. Gutierrez et al. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
- Blue light induced A2E oxidation in rat eyes – experimental animal model of dry AMD
- (2010) A. R. Wielgus et al. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
- The pharmacokinetic profile of crocetin in healthy adult human volunteers after a single oral administration
- (2010) N. Umigai et al. PHYTOMEDICINE
- Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration
- (2010) Y. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARγ activation
- (2009) Nobuyuki Takahashi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A2E, a component of lipofuscin, is pro-angiogenic in vivo
- (2009) Aya Iriyama et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Retinal carotenoids can attenuate formation of A2E in the retinal pigment epithelium
- (2008) Prakash Bhosale et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance
- (2008) Akiko Maeda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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