ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y1 Purinergic Receptor via a YPX3L Motif

G Protein-coupled Receptor (GPCR) Signaling via Heterotrimeric G Proteins from Endosomes

(2015) Nikoleta G. Tsvetanova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes

(2015) Neil J. Grimsey et al.   JOURNAL OF CELL BIOLOGY

Novel insights into G protein and G protein-coupled receptor signaling in cancer

(2014) Morgan O’Hayre et al.   CURRENT OPINION IN CELL BIOLOGY

RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation

(2014) C. L. Freeman et al.   JOURNAL OF CELL SCIENCE

Viral Infection Controlled by a Calcium-Dependent Lipid-Binding Module in ALIX

(2013) Christin Bissig et al.   DEVELOPMENTAL CELL

Structure-based in silico identification of ubiquitin-binding domains provides insights into the ALIX-V:ubiquitin complex and retrovirus budding

(2013) Tal Keren-Kaplan et al.   EMBO JOURNAL

ALIX and the multivesicular endosome: ALIX in Wonderland

(2013) Christin Bissig et al.   TRENDS IN CELL BIOLOGY

Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules

(2012) Jan R T van Weering et al.   EMBO JOURNAL

ALIX binds a YPX3L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting

(2012) Michael R. Dores et al.   JOURNAL OF CELL BIOLOGY

The GPCR Network: a large-scale collaboration to determine human GPCR structure and function

(2012) Raymond C. Stevens et al.   NATURE REVIEWS DRUG DISCOVERY

New insights from structural biology into the druggability of G protein-coupled receptors

(2012) Jonathan S. Mason et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Activation of the P2Y1 receptor induces apoptosis and inhibits proliferation of prostate cancer cells

(2011) Qiang Wei et al.   BIOCHEMICAL PHARMACOLOGY

β2-Adrenergic Receptor Lysosomal Trafficking Is Regulated by Ubiquitination of Lysyl Residues in Two Distinct Receptor Domains

(2011) Kunhong Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

(2011) Gregory D. Fairn et al.   JOURNAL OF CELL BIOLOGY

Ca2+ signalling by P2Y receptors in cultured rat aortic smooth muscle cells

(2010) Sriram Govindan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of Human VPS4A by ESCRT-III Proteins Reveals Ability of Substrates to Relieve Enzyme Autoinhibition

(2010) Samuel A. Merrill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dysbindin Promotes the Post-Endocytic Sorting of G Protein-Coupled Receptors to Lysosomes

(2010) Aaron Marley et al.   PLoS One

Regulation of P2Y1 Receptor Traffic by Sorting Nexin 1 is Retromer Independent

(2010) Shaista Nisar et al.   TRAFFIC

Structure and Function of the ESCRT-II-III Interface in Multivesicular Body Biogenesis

(2009) Young Jun Im et al.   DEVELOPMENTAL CELL

 -Arrestin-2 Interaction and Internalization of the Human P2Y1 Receptor Are Dependent on C-Terminal Phosphorylation Sites

(2009) S. Reiner et al.   MOLECULAR PHARMACOLOGY

Membrane scission by the ESCRT-III complex

(2009) Thomas Wollert et al.   NATURE

A Crescent-Shaped ALIX Dimer Targets ESCRT-III CHMP4 Filaments

(2009) Ricardo Pires et al.   STRUCTURE

ADP Stimulates Human Endothelial Cell Migration via P2Y 1 Nucleotide Receptor–Mediated Mitogen-Activated Protein Kinase Pathways

(2008) Jianzhong Shen et al.   CIRCULATION RESEARCH

Trafficking and function of the tetraspanin CD63

(2008) Maaike S. Pols et al.   EXPERIMENTAL CELL RESEARCH

Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release

(2008) J. G. Carlton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALIX-CHMP4 interactions in the human ESCRT pathway

(2008) J. McCullough et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helical Structures of ESCRT-III Are Disassembled by VPS4

(2008) S. Lata et al.   SCIENCE

G Protein–Coupled Receptor Sorting to Endosomes and Lysosomes

(2007) Adriano Marchese et al.   Annual Review of Pharmacology and Toxicology