Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy
出版年份 2016 全文链接
标题
Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy
作者
关键词
Radiation therapy, Cancer immunotherapy, Cancer treatment, T cells, Immune response, Mouse models, Regulatory T cells, Antibodies
出版物
PLoS One
Volume 11, Issue 6, Pages e0157164
出版商
Public Library of Science (PLoS)
发表日期
2016-06-10
DOI
10.1371/journal.pone.0157164
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions
- (2015) A. Filatenkov et al. CLINICAL CANCER RESEARCH
- 30 Gy or 34 Gy? Comparing 2 Single-Fraction SBRT Dose Schedules for Stage I Medically Inoperable Non-Small Cell Lung Cancer
- (2014) Gregory M.M. Videtic et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Irradiation and anti–PD-L1 treatment synergistically promote antitumor immunity in mice
- (2014) Liufu Deng et al. JOURNAL OF CLINICAL INVESTIGATION
- Spine stereotactic body radiotherapy for renal cell cancer spinal metastases: analysis of outcomes and risk of vertebral compression fracture
- (2014) Isabelle Thibault et al. JOURNAL OF NEUROSURGERY-SPINE
- The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
- (2014) Peter M. K. Westcott et al. NATURE
- Focal Radiation Therapy Combined with 4-1BB Activation and CTLA-4 Blockade Yields Long-Term Survival and a Protective Antigen-Specific Memory Response in a Murine Glioma Model
- (2014) Zineb Belcaid et al. PLoS One
- A Systemic Complete Response of Metastatic Melanoma to Local Radiation and Immunotherapy
- (2014) Susan M. Hiniker et al. Translational Oncology
- OX40 Is a Potent Immune-Stimulating Target in Late-Stage Cancer Patients
- (2013) B. D. Curti et al. CANCER RESEARCH
- Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
- (2013) Tyler R. Simpson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy
- (2013) Paula D. Bos et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Radiation-Induced Equilibrium Is a Balance between Tumor Cell Proliferation and T Cell-Mediated Killing
- (2013) H. Liang et al. JOURNAL OF IMMUNOLOGY
- The Peripheral Myeloid Expansion Driven by Murine Cancer Progression Is Reversed by Radiation Therapy of the Tumor
- (2013) Marka R. Crittenden et al. PLoS One
- Anti-CTLA-4 Antibodies of IgG2a Isotype Enhance Antitumor Activity through Reduction of Intratumoral Regulatory T Cells
- (2013) M. J. Selby et al. Cancer Immunology Research
- Concurrent Radiotherapy and Ipilimumab Immunotherapy for Patients with Melanoma
- (2013) C. A. Barker et al. Cancer Immunology Research
- Combined Targeting of Costimulatory (OX40) and Coinhibitory (CTLA-4) Pathways Elicits Potent Effector T Cells Capable of Driving Robust Antitumor Immunity
- (2013) W. L. Redmond et al. Cancer Immunology Research
- Immune system plays an important role in the success and failure of conventional cancer therapy
- (2012) Michael J Gough et al. Immunotherapy
- Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma
- (2012) Michael A. Postow et al. NEW ENGLAND JOURNAL OF MEDICINE
- Expression of NF-κB p50 in Tumor Stroma Limits the Control of Tumors by Radiation Therapy
- (2012) Marka R. Crittenden et al. PLoS One
- CTLA4 Blockade Induces Frequent Tumor Infiltration by Activated Lymphocytes Regardless of Clinical Responses in Humans
- (2011) R. R. Huang et al. CLINICAL CANCER RESEARCH
- Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy
- (2011) David G. DeNardo et al. Cancer Discovery
- Tumor Regression and Growth Rates Determined in Five Intramural NCI Prostate Cancer Trials: The Growth Rate Constant as an Indicator of Therapeutic Efficacy
- (2010) W. D. Stein et al. CLINICAL CANCER RESEARCH
- Adjuvant Therapy With Agonistic Antibodies to CD134 (OX40) Increases Local Control After Surgical or Radiation Therapy of Cancer in Mice
- (2010) Michael J. Gough et al. JOURNAL OF IMMUNOTHERAPY
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment
- (2009) Y. Lee et al. BLOOD
- Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti-CTLA-4 Antibody
- (2009) M. Z. Dewan et al. CLINICAL CANCER RESEARCH
- OX40 Agonist Therapy Enhances CD8 Infiltration and Decreases Immune Suppression in the Tumor
- (2008) M. J. Gough et al. CANCER RESEARCH
- Anti-OX40 monoclonal antibody therapy in combination with radiotherapy results in therapeutic antitumor immunity to murine lung cancer
- (2008) Hiroshi Yokouchi et al. CANCER SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started