The mutational landscapes of genetic and chemical models of Kras-driven lung cancer

Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing

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Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

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Emerging landscape of oncogenic signatures across human cancers

(2013) Giovanni Ciriello et al.   NATURE GENETICS

Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer

(2013) S. Fawdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Genome Landscapes

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A Comprehensive Survey of Ras Mutations in Cancer

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Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers

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Mutational Processes Molding the Genomes of 21 Breast Cancers

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The Origin and Evolution of Mutations in Acute Myeloid Leukemia

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Molecular analysis of point mutations in a barley genome exposed to MNU and gamma rays

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Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis

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Identification of Fat4 and Tsc22d1 as Novel Candidate Genes for Spontaneous Pulmonary Adenomas

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Progressive Genomic Instability in the FVB/KrasLA2 Mouse Model of Lung Cancer

(2011) M. D. To et al.   MOLECULAR CANCER RESEARCH

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

(2011) Ignacio Varela et al.   NATURE

A framework for variation discovery and genotyping using next-generation DNA sequencing data

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Control-free calling of copy number alterations in deep-sequencing data using GC-content normalization

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Mechanisms of lung tumorigenesis by ethyl carbamate and vinyl carbamate

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ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

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COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

The Sequence Alignment/Map format and SAMtools

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Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer

(2008) Minh D To et al.   NATURE GENETICS

Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study

(2008) Kerby Shedden et al.   NATURE MEDICINE