Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

High-throughput phosphoproteomics reveals in vivo insulin signaling dynamics

(2015) Sean J Humphrey et al.   NATURE BIOTECHNOLOGY

Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation

(2015) K. B. Emdal et al.   Science Signaling

A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation

(2015) Guang Yang et al.   Cell Reports

Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation

(2015) K. B. Emdal et al.   Science Signaling

A generalised enzyme kinetic model for predicting the behaviour of complex biochemical systems

(2015) Martin Kin Lok Wong et al.   FEBS Open Bio

Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO2 and Ti-IMAC

(2014) Christopher J. Tape et al.   ANALYTICAL CHEMISTRY

Eukaryotic Elongation Factor 2 Kinase Activity Is Controlled by Multiple Inputs from Oncogenic Signaling

(2014) X. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Data-driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states

(2014) S. Ahmed et al.   Molecular Systems Biology

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling

(2014) Kirti Sharma et al.   Cell Reports

Insulin Signaling in Type 2 Diabetes

(2013) Cecilia Brännmark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic Analysis of Protein Phosphorylation Networks From Phosphoproteomic Data

(2012) Chunxia Song et al.   MOLECULAR & CELLULAR PROTEOMICS

Rapamycin sensitive mTOR activation mediates nerve growth factor (NGF) induced cell migration and pro-survival effects against hydrogen peroxide in retinal pigment epithelial cells

(2011) Guo-Fan Cao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mapping Insulin/GLUT4 Circuitry

(2011) Alexander F. Rowland et al.   TRAFFIC

Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

(2010) J. V. Olsen et al.   Science Signaling

The nuts and bolts of AGC protein kinases

(2009) Laura R. Pearce et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY