Dissecting the Mechanisms of Doxorubicin and Oxidative Stress-Induced Cytotoxicity: The Involvement of Actin Cytoskeleton and ROCK1

The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure

(2014) Merry L. Lindsey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Prevention of Anthracycline-Induced Cardiotoxicity

(2014) Pimprapa Vejpongsa et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

(2014) Tomáš Šimůnek et al.   Pharmacological Reports

ROCK1 Deficiency Enhances Protective Effects of Antioxidants against Apoptosis and Cell Detachment

(2014) Michelle Surma et al.   PLoS One

The chemistry and biological activities of N-acetylcysteine

(2013) Yuval Samuni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Dissecting the roles of ROCK isoforms in stress-induced cell detachment

(2013) Jianjian Shi et al.   CELL CYCLE

Treatment-related cardiotoxicity in survivors of childhood cancer

(2013) Steven E. Lipshultz et al.   Nature Reviews Clinical Oncology

Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment

(2013) Jianjian Shi et al.   Cell Death & Disease

Downregulation of doxorubicin-induced myocardial apoptosis accompanies postnatal heart maturation

(2012) Jianjian Shi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Juvenile Exposure to Anthracyclines Impairs Cardiac Progenitor Cell Function and Vascularization Resulting in Greater Susceptibility to Stress-Induced Myocardial Injury in Adult Mice

(2010) Chengqun Huang et al.   CIRCULATION

Mechanisms of Anthracycline Cardiac Injury: Can We Identify Strategies for Cardioprotection?

(2010) Douglas B. Sawyer et al.   PROGRESS IN CARDIOVASCULAR DISEASES

N-Acetylcysteine Inhibits RhoA and Promotes Apoptotic Cell Clearance during Intense Lung Inflammation

(2009) Changsuk Moon et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cardiomyocyte death in doxorubicin-induced cardiotoxicity

(2009) Yi-Wei Zhang et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Anthracycline Cardiomyopathy Is Mediated by Depletion of the Cardiac Stem Cell Pool and Is Rescued by Restoration of Progenitor Cell Function

(2009) Antonella De Angelis et al.   CIRCULATION

Effect of cytoskeleton inhibitors on deadhesion kinetics of HepG2 cells on biomimetic surface

(2009) Zhiqin Feng et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Activation of the ubiquitin-proteasome system in doxorubicin cardiomyopathy

(2009) Mark J. Ranek et al.   CURRENT HYPERTENSION REPORTS

Cardiovascular Complications of Cancer Therapy

(2009) Edward T.H. Yeh et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Direct Activation of RhoA by Reactive Oxygen Species Requires a Redox-Sensitive Motif

(2009) Amir Aghajanian et al.   PLoS One

Acute Doxorubicin Cardiotoxicity Is Associated With p53-Induced Inhibition of the Mammalian Target of Rapamycin Pathway

(2008) Wuqiang Zhu et al.   CIRCULATION

A Mouse Model for Juvenile Doxorubicin-Induced Cardiac Dysfunction

(2008) Wuqiang Zhu et al.   PEDIATRIC RESEARCH