Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment

Downregulation of doxorubicin-induced myocardial apoptosis accompanies postnatal heart maturation

(2012) Jianjian Shi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53

(2012) S. Vemula et al.   BLOOD

Regulation of Glucose Transport by ROCK1 Differs from That of ROCK2 and Is Controlled by Actin Polymerization

(2012) Kwang-Hoon Chun et al.   ENDOCRINOLOGY

Rho Kinase Regulates the Survival and Transformation of Cells Bearing Oncogenic Forms of KIT, FLT3, and BCR-ABL

(2011) Raghuveer Singh Mali et al.   CANCER CELL

Rho-Kinase in Development and Heart Failure: Insights From Genetic Models

(2011) Jianjian Shi et al.   PEDIATRIC CARDIOLOGY

Inhibition of ROCK improves survival of human embryonic stem cell-derived cardiomyocytes after dissociation

(2010) Stefan R. Braam et al.   Annals of the New York Academy of Sciences

RhoA/Rho-kinase and vascular diseases: what is the link?

(2010) Kenia Pedrosa Nunes et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity

(2010) Mutsuki Amano et al.   Cytoskeleton

Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases

(2010) Ming Dong et al.   DRUG DISCOVERY TODAY

RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis

(2010) Brad A. Bryan et al.   FASEB JOURNAL

ROCK1 plays an essential role in the transition from cardiac hypertrophy to failure in mice

(2010) Jianjian Shi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Rho-associated kinase-dependent contraction of stress fibres and the organization of focal adhesions

(2010) K. Katoh et al.   Journal of the Royal Society Interface

The role of Rho protein signaling in hypertension

(2010) Gervaise Loirand et al.   Nature Reviews Cardiology

Mechanisms of Anthracycline Cardiac Injury: Can We Identify Strategies for Cardioprotection?

(2010) Douglas B. Sawyer et al.   PROGRESS IN CARDIOVASCULAR DISEASES

New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion

(2010) A. Zagorska et al.   Science Signaling

Revisited and Revised: Is RhoA Always a Villain in Cardiac Pathophysiology?

(2010) Shigeki Miyamoto et al.   Journal of Cardiovascular Translational Research

Cardiomyocyte death in doxorubicin-induced cardiotoxicity

(2009) Yi-Wei Zhang et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity

(2009) C. Hahmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ROCK Isoform Regulation of Myosin Phosphatase and Contractility in Vascular Smooth Muscle Cells

(2009) Yuepeng Wang et al.   CIRCULATION RESEARCH

Effect of cytoskeleton inhibitors on deadhesion kinetics of HepG2 cells on biomimetic surface

(2009) Zhiqin Feng et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Inhibition of Caspase-mediated Anoikis Is Critical for Basic Fibroblast Growth Factor-sustained Culture of Human Pluripotent Stem Cells

(2009) Xiaofang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Rho Kinase Isoforms in Lung Endothelial Cells during Inflammation

(2009) P. Y. Mong et al.   JOURNAL OF IMMUNOLOGY

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct Roles for ROCK1 and ROCK2 in the Regulation of Keratinocyte Differentiation

(2009) Frances E. Lock et al.   PLoS One

Applications for ROCK kinase inhibition

(2008) Michael F Olson   CURRENT OPINION IN CELL BIOLOGY

Inhibition of the Rho/ROCK pathway reduces apoptosis during transplantation of embryonic stem cell-derived neural precursors

(2007) Masaomi Koyanagi et al.   JOURNAL OF NEUROSCIENCE RESEARCH