Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility

Direct Interactions with the Integrin β1 Cytoplasmic Tail Activate the Abl2/Arg Kinase

(2015) Mark A. Simpson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting ABL1-Mediated Oxidative Stress Adaptation in Fumarate Hydratase-Deficient Cancer

(2014) Carole Sourbier et al.   CANCER CELL

A Molecular Switch for the Orientation of Epithelial Cell Polarization

(2014) David M. Bryant et al.   DEVELOPMENTAL CELL

Dynamic Reprogramming of Signaling Upon Met Inhibition Reveals a Mechanism of Drug Resistance in Gastric Cancer

(2014) A. Z. Lai et al.   Science Signaling

Targeting the MET gene for the treatment of non-small-cell lung cancer

(2013) F. Gelsomino et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Arg kinase signaling in dendrite and synapse stabilization pathways: Memory, cocaine sensitivity, and stress

(2013) Meghan E. Kerrisk et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Abl2/Arg Controls Dendritic Spine and Dendrite Arbor Stability via Distinct Cytoskeletal Control Pathways

(2013) Y.-C. Lin et al.   JOURNAL OF NEUROSCIENCE

β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation

(2013) Brian T. Beaty et al.   MOLECULAR BIOLOGY OF THE CELL

The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer

(2013) H Zhao et al.   ONCOGENE

Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival

(2013) E. M. Chislock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer

(2013) J. F. Knight et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer

(2012) James S. Duncan et al.   CELL

Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

(2012) Timothy R. Wilson et al.   NATURE

Nilotinib and MEK Inhibitors Induce Synthetic Lethality through Paradoxical Activation of RAF in Drug-Resistant Chronic Myeloid Leukemia

(2011) Leisl M. Packer et al.   CANCER CELL

Abl interconnects oncogenic Met and p53 core pathways in cancer cells

(2011) A Furlan et al.   CELL DEATH AND DIFFERENTIATION

Arg Kinase Regulates Epithelial Cell Polarity by Targeting β1-Integrin and Small GTPase Pathways

(2011) Ran Li et al.   CURRENT BIOLOGY

HGF-independent potentiation of EGFR action by c-Met

(2011) A M Dulak et al.   ONCOGENE

c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways and drive metastatic progression

(2011) S S Ganguly et al.   ONCOGENE

Acquired Resistance of Non-Small Cell Lung Cancer Cells to MET Kinase Inhibition Is Mediated by a Switch to Epidermal Growth Factor Receptor Dependency

(2010) U. McDermott et al.   CANCER RESEARCH

Abl Kinases Are Required for Invadopodia Formation and Chemokine-induced Invasion

(2010) Pameeka S. Smith-Pearson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

(2010) Jianming Zhang et al.   NATURE

MET signalling: principles and functions in development, organ regeneration and cancer

(2010) Livio Trusolino et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ABL Tyrosine Kinases: Evolution of Function, Regulation, and Specificity

(2010) J. Colicelli   Science Signaling

Reciprocal regulation of Abl and receptor tyrosine kinases

(2009) Divyamani Srinivasan et al.   CELLULAR SIGNALLING

Resistance to EGF-R (erbB-1) and VEGF-R modulating agents

(2009) Wolfram C.M. Dempke et al.   EUROPEAN JOURNAL OF CANCER

Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts

(2009) W. D. Bradley et al.   JOURNAL OF CELL SCIENCE

Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC

(2009) D Wu et al.   ONCOGENE

Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer

(2009) M. G. Ponzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developing c-MET pathway inhibitors for cancer therapy: progress and challenges

(2009) Xiangdong Liu et al.   TRENDS IN MOLECULAR MEDICINE

Met and c-Src Cooperate to Compensate for Loss of Epidermal Growth Factor Receptor Kinase Activity in Breast Cancer Cells

(2008) K. L. Mueller et al.   CANCER RESEARCH

Met Receptor Contributes to Trastuzumab Resistance of Her2-Overexpressing Breast Cancer Cells

(2008) D. L. Shattuck et al.   CANCER RESEARCH

Abl Kinases Regulate Autophagy by Promoting the Trafficking and Function of Lysosomal Components

(2008) Gouri Yogalingam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drug development of MET inhibitors: targeting oncogene addiction and expedience

(2008) Paolo M. Comoglio et al.   NATURE REVIEWS DRUG DISCOVERY

Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells

(2008) M. Emaduddin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA